Mối liên hệ giữa nồng độ insulin-like growth factor-I trong huyết thanh và sự tích lũy khoáng chất xương ở trẻ em tuổi dậy thì: một nghiên cứu theo dõi 3 năm tại Hamamatsu, Nhật Bản
Tóm tắt
Dữ liệu dịch tễ học về mối liên hệ giữa nồng độ IGF-I trong huyết thanh và sự tích lũy khoáng chất xương trong thời thơ ấu còn khan hiếm. Tại đây, chúng tôi đã điều tra mối liên hệ giữa nồng độ IGF-I trong huyết thanh và tình trạng xương trong thời kỳ dậy thì.
Chúng tôi đã phân tích dữ liệu theo dõi 3 năm từ 254 trẻ em sống trong cộng đồng, những người đã hoàn thành cả hai khảo sát cơ bản (tại độ tuổi 11,2) và theo dõi (tại độ tuổi 14,2) tại Hamamatsu, Nhật Bản. Diện tích xương toàn bộ (TB) và các tham số về khoáng chất xương được đánh giá bằng phương pháp hấp thụ tia X năng lượng kép.
Trong thời gian theo dõi 3 năm, có sự gia tăng đáng kể (
Những kết quả này gợi ý rằng trẻ em tuổi dậy thì có nồng độ IGF-I trong huyết thanh cao có xu hướng có được sự tích lũy khoáng chất xương cao hơn vào những giai đoạn sau.
Từ khóa
Tài liệu tham khảo
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