Association of vitamin D deficiency and anemia in a hospitalized geriatric population: denutrition as a confounding factor

Annals of Hematology - Tập 92 - Trang 615-619 - 2012
A. Coutard1,2, R. Garlantézec2,3, S. Estivin1,2, M. Andro1,2, A. Gentric1,2
1Acute Geriatric Unit Teaching Hospital, CHRU Brest, Brest, France
2Faculty of Medicine, European University of Brittany, Brest, France
3Public Health Department, CHRU Brest, Brest, France

Tóm tắt

This study aimed to investigate the association between vitamin D deficiency and anemia in a hospitalized geriatric population. An observational study, at the acute care geriatric unit of Brest Hospital, France, was conducted among 226 patients aged ≥70 years consecutively hospitalized between January 22, 2010 and August 9, 2010. Vitamin D and hemoglobin levels were measured. Vitamin D deficiency was defined as a 25(OH)D level <50 nmol/L and anemia as defined by the World Health Organization. After adjustment for albuminemia, anemia was not significantly associated with vitamin D deficiency (odds ratio (OR) = 1.37; 95 % confidence interval (CI) = 0.72–2.6). But anemia was significantly associated with hypoalbuminemia (OR = 2.08; 95 % CI = 1.11–3.91). Denutrition reflected by hypoalbuminemia could be a possible confounding factor in the previously described association between anemia and vitamin D deficiency.

Tài liệu tham khảo

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