Association of Neutrophil–Lymphocyte Ratio With the Presence and Severity of Rheumatic Mitral Valve Stenosis

Clinical and Applied Thrombosis/Hemostasis - Tập 20 Số 8 - Trang 793-798 - 2014
Nihat Polat1, Abdülkadir Yıldız1, Murat Yüksel1, Mehmet Zihni Bilik1, Mesut Aydın1, Halit Acet1, Mehmet Ata Akıl1, Mustafa Oylumlu1, Hasan Kaya1, Faruk Ertaş1, Habib Çil1
1Department of Cardiology, Dicle University School of Medicine, Diyarbakir, Turkey

Tóm tắt

The aim of the study is to investigate the association between the severity of rheumatic mitral valvular disease (RMVD) and the neutrophil–lymphocyte ratio (NLR). A total of 227 patients were enrolled in the study and divided into 3 groups. Patients in group 1 had rheumatic mitral stenosis (RMS), those in group 2 had RMVD without stenosis, and those in group 3 served as the control group. Group 1 was further divided into 2 groups, severe mitral stenosis (MS) and mild to moderate MS. The NLR was significantly higher in patients with severe MS when compared to those with mild to moderate MS ( P = .002) while lymphocyte count was lower ( P = .034). Using a cutoff level of 2.56, the NLR predicted severe RMS with a sensitivity of 75% and specificity of 74%. In conclusion, as an inexpensive, simple, and accessible marker of inflammation, the NLR may be useful in predicting the presence and severity of MS in patients with RMVD.

Từ khóa


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Thông tin xuất bản

Clinical and Applied Thrombosis/Hemostasis

Tập 20 Số 8

793-798

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