Association of NAT2, GST and CYP2E1 polymorphisms and anti-tuberculosis drug-induced hepatotoxicity

Tuberculosis - Tập 94 - Trang 293-298 - 2014
Neha Singla1, Dheeraj Gupta2, Niti Birbian1, Jagtar Singh1
1Department of Biotechnology, Panjab University, Chandigarh, 160014, India
2Department of Pulmonary Medicine, PGIMER, Chandigarh 160012, India

Tài liệu tham khảo

Smith, 1999, Stop TB: is DOTS the answer?, Indian J Tuberc, 46, 81 Arora, 2002, DOTS strategy in India – the challenges, Curr Med J North Zone, 8, 19 Higuchi, 2007, NAT2 6A, a haplotype of the N-acetyltransferase 2 gene, is an important biomarker for risk of anti-tuberculosis drug-induced hepatotoxicity in Japanese patients with tuberculosis, World J Gastroenterol, 13, 6003, 10.3748/wjg.13.6003 Teixeira, 2011, Genetic polymorphisms of NAT2, CYP2E1 and GST enzymes and the occurrence of antituberculosis drug-induced hepatitis in Brazilian TB patients, Mem Inst Oswaldo Cruz, 106, 716, 10.1590/S0074-02762011000600011 Mitchell, 1975, Increased incidence of isoniazid hepatitis in rapid acetylators: possible relation to hydranize metabolites, Clin Pharmacol Ther, 18, 70, 10.1002/cpt197518170 Nelson, 1976, Isoniazid and iproniazid: activation of metabolites to toxic intermediates in man and rat, Science, 193, 901, 10.1126/science.7838 Timbrell, 1982, Studies on hydrazine hepatotoxicity. 2. Biochemical findings, J Toxicol Environ Health, 10, 955, 10.1080/15287398209530309 Lee, 2003, Drug-induced hepatotoxicity, N Engl J Med, 349, 474, 10.1056/NEJMra021844 Santos, 2013, N-acetyl transferase 2 and cytochrome P450 2E1 genes and isoniazid-induced hepatotoxicity in Brazilian patients, Int J Tuberc Lung Dis, 17, 499, 10.5588/ijtld.12.0645 Chen, 2006, The influence of various genotypes on the metabolic activity of NAT2 in Chinese population, Eur J Clin Pharmacol, 62, 355, 10.1007/s00228-006-0110-6 Kinzig-Schippers, 2005, Should we use N-acetyltransferase type 2 genotyping to personalize isoniazid doses?, Antimicrob Agents Chemother, 49, 1733, 10.1128/AAC.49.5.1733-1738.2005 Singh, 1995, Antituberculosis treatment-induced hepatotoxicity: role of predictive factors, Postgrad Med J, 71, 359, 10.1136/pgmj.71.836.359 Lee, 2010, NAT2 and CYP2E1 polymorphisms and susceptibility to first-line anti-tuberculosis drug-induced hepatitis, Int J Tuberc Lung Dis, 14, 622 Bose, 2011, Role of polymorphic N-acetyl transferase2 and cytochrome P4502E1 gene in antituberculosis treatment-induced hepatitis, J Gastroenterol Hepatol, 26, 312, 10.1111/j.1440-1746.2010.06355.x Roy, 2001, Increased risk of antituberculosis drug-induced hepatotoxicity in individuals with glutathione S-transferase M1 ‘null’ mutation, J Gastroenterol Hepatol, 16, 1033, 10.1046/j.1440-1746.2001.02585.x Vuilleumier, 2006, CYP2E1 genotype and isoniazid-induced hepatotoxicity in patients treated for latent tuberculosis, Eur J Clin Pharmacol, 62, 423, 10.1007/s00228-006-0111-5 Du, 2013, Slow N-acetyltransferase 2 genotype contributes to anti-tuberculosis drug-induced hepatotoxicity: a meta-analysis, Mol Biol Rep, 40, 3591, 10.1007/s11033-012-2433-y Mitchel, 1973, Acetaminophen induced hepatic necrosis. IV. Protective role of glutathione, J Pharmacol Exp Ther, 187, 211 Hussey, 1991, Variation in the expression of mu-class glutathione S-transferase isoenzymes from human skeletal muscle, Biochem J, 273, 323, 10.1042/bj2730323 Huang, 2003, Cytochome P4502E1 genotype and the susceptibility to antituberculosis drug-induced hepatitis, Hepatology, 37, 924, 10.1053/jhep.2003.50144 Huang, 2007, Genetic polymorphisms of manganese superoxide dismutase, NAD(P)H:quinone oxidoreductase, glutathione S-transferase M1 and T1, and the susceptibility to drug-induced liver injury, J Hepatol, 47, 128, 10.1016/j.jhep.2007.02.009 Sun, 2013, GSTM1 and GSTT1 null polymorphisms and susceptibility to anti-tuberculosis drug-induced liver injury: a meta-analysis, Int J Tuberc Lung Dis, 17, 17, 10.5588/ijtld.12.0447 Leiro, 2008, Influence of glutathione S-transferase M1 and T1 homozygous null mutations on the risk of antituberculosis drug-induced hepatotoxicity in a Caucasian population, Liver Int, 28, 835, 10.1111/j.1478-3231.2008.01700.x Ladero, 1996, RsaI polymorphism at the cytochrome P4502E1 locus and risk of hepatocellular carcinoma, Gut, 39, 330, 10.1136/gut.39.2.330 Benichou, 1990, Criteria of drug-induced liver disorders. Report of an international consensus meeting, J Hepatol, 11, 272, 10.1016/0168-8278(90)90124-A Prati, 2002, Updated definitions of healthy ranges for serum alanine aminotransferase levels, Ann Intern Med, 137, 1, 10.7326/0003-4819-137-1-200207020-00006 Roe, 1996 Fukino, 2008, Effects of N-acetyltransferase 2 (NAT2), CYP2E1 and Glutathione-S-transferase (GST) genotypes on the serum concentrations of isoniazid and metabolites in tuberculosis patients, J Toxicol Sci, 33, 187, 10.2131/jts.33.187 Sobti, 2006, Interaction of passive smoking with GST (GSTM1, GSTT1, and GSTP1) genotypes in the risk of cervical cancer in India, Cancer Genet Cytogenet, 166, 117, 10.1016/j.cancergencyto.2005.10.001 Purcell, 2007, PLINK: a toolset for whole-genome association and population-based linkage analysis, Am J Hum Genet, 81, 559, 10.1086/519795 Barrett, 2005, Haploview: analysis and visualization of LD and haplotype maps, Bioinformatics, 21, 263, 10.1093/bioinformatics/bth457 Pande, 1996, Risk factors for hepatotoxicity from antituberculosis drugs: a case-control study, Thorax, 51, 132, 10.1136/thx.51.2.132 Kumar, 2010, Antituberculosis therapy-induced acute liver failure: magnitude, profile, prognosis, and predictors of outcome, Hepatology, 51, 1665, 10.1002/hep.23534 Cho, 2007, Genetic polymorphisms of NAT2 and CYP2E1 associated with antituberculosis drug-induced hepatotoxicity in Korean patients with pulmonary tuberculosis, Tuberculosis (Edinb), 87, 551, 10.1016/j.tube.2007.05.012 Huang, 2002, Polymorphism of the N-acetyltransferase 2 gene as a susceptibility risk factor for antituberculosis drug-induced hepatitis, Hepatology, 35, 883, 10.1053/jhep.2002.32102 Sodhi, 1996, Study of oxidative stress in isoniazid induced hepatic injury in young rats with and without protein energy malnutrition, J Biochem Toxicol, 11, 139, 10.1002/(SICI)1522-7146(1996)11:3<139::AID-JBT6>3.0.CO;2-L Chatterjee, 2010, GSTT1 and GSTM1 gene deletions are not associated with hepatotoxicity caused by antitubercular drugs, J Clin Pharm Ther, 35, 65 Li, 2013, GSTM1 and GSTT1 genetic polymorphisms and risk of anti-tuberculosis drug-induced hepatotoxicity: an updated meta-analysis, Eur J Clin Microbiol Infect Dis, 10.1007/s10096-013-1831-y Deka, 2010, Role of CYP2E1 gene polymorphisms association with hepatitis risk in Northeast India, World J Gastroenterol, 16, 4800, 10.3748/wjg.v16.i38.4800 Kim, 1995, Interindividual variability o f chlorzoxazone 6-hydroxylation in men and women and its relationship to CYP2E1 genetic polymorphisms, Clin Pharmacol Ther, 57, 645, 10.1016/0009-9236(95)90227-9 Singh, 2009, Study of NAT2 gene polymorphisms in an Indian population: association with plasma isoniazid concentration in a cohort of tuberculosis patients, Mol Diagn Ther, 13, 49, 10.1007/BF03256314 Anitha, 2003, Arylamine N-acetyltransferase 2 polymorphism in the ethnic populations of South India, Int J Mol Med, 11, 125 Sabbagh, 2011, Arylamine N-acetyltransferase2 (NAT2) genetic diversity and traditional subsistence: a worldwide population survey, PLoS One, 6, e18507, 10.1371/journal.pone.0018507 World Health Organization, 2010 Acharya, 1996, Fulminant hepatitis in a tropical population: clinical course, cause and early predictors of outcome, Hepatology, 23, 1448, 10.1002/hep.510230622