Association of Human Papillomavirus Status at Head and Neck Carcinoma Subsites With Overall Survival

Ang, 2012, Human papillomavirus as a marker of the natural history and response to therapy of head and neck squamous cell carcinoma., Semin Radiat Oncol, 22, 128, 10.1016/j.semradonc.2011.12.004

Deschler, 2014, The “new” head and neck cancer patient-young, nonsmoker, nondrinker, and HPV positive: evaluation., Otolaryngol Head Neck Surg, 151, 375, 10.1177/0194599814538605

Chaturvedi, 2011, Human papillomavirus and rising oropharyngeal cancer incidence in the United States., J Clin Oncol, 29, 4294, 10.1200/JCO.2011.36.4596

Anantharaman, 2017, Geographic heterogeneity in the prevalence of human papillomavirus in head and neck cancer., Int J Cancer, 140, 1968, 10.1002/ijc.30608

Licitra, 2006, High-risk human papillomavirus affects prognosis in patients with surgically treated oropharyngeal squamous cell carcinoma., J Clin Oncol, 24, 5630, 10.1200/JCO.2005.04.6136

Fakhry, 2008, Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial., J Natl Cancer Inst, 100, 261, 10.1093/jnci/djn011

Rischin, 2010, Prognostic significance of p16INK4A and human papillomavirus in patients with oropharyngeal cancer treated on TROG 02.02 phase III trial., J Clin Oncol, 28, 4142, 10.1200/JCO.2010.29.2904

Ang, 2010, Human papillomavirus and survival of patients with oropharyngeal cancer., N Engl J Med, 363, 24, 10.1056/NEJMoa0912217

Marcu, 2016, Future treatment directions for HPV-associated head and neck cancer based on radiobiological rationale and current clinical evidence., Crit Rev Oncol Hematol, 103, 27, 10.1016/j.critrevonc.2016.05.002

Weaver, 2015, DNA double strand break repair defect and sensitivity to poly ADP-ribose polymerase (PARP) inhibition in human papillomavirus 16-positive head and neck squamous cell carcinoma., Oncotarget, 6, 26995, 10.18632/oncotarget.v6i29

Rieckmann, 2013, HNSCC cell lines positive for HPV and p16 possess higher cellular radiosensitivity due to an impaired DSB repair capacity., Radiother Oncol, 107, 242, 10.1016/j.radonc.2013.03.013

Quon, 2013, Controversies in treatment deintensification of human papillomavirus-associated oropharyngeal carcinomas: should we, how should we, and for whom?, J Clin Oncol, 31, 520, 10.1200/JCO.2012.46.7746

Frank, 2010, Intensity-modulated radiotherapy for cervical node squamous cell carcinoma metastases from unknown head-and-neck primary site: M. D. Anderson Cancer Center outcomes and patterns of failure., Int J Radiat Oncol Biol Phys, 78, 1005, 10.1016/j.ijrobp.2009.09.006

Chen, 2011, Improved dosimetric and clinical outcomes with intensity-modulated radiotherapy for head-and-neck cancer of unknown primary origin., Int J Radiat Oncol Biol Phys, 79, 756, 10.1016/j.ijrobp.2009.11.020

Shoushtari, 2011, Outcomes of patients with head-and-neck cancer of unknown primary origin treated with intensity-modulated radiotherapy., Int J Radiat Oncol Biol Phys, 81, e83, 10.1016/j.ijrobp.2011.01.014

Combes, 2014, Role of human papillomavirus in non-oropharyngeal head and neck cancers., Oral Oncol, 50, 370, 10.1016/j.oraloncology.2013.11.004

Isayeva, 2012, Human papillomavirus in non-oropharyngeal head and neck cancers: a systematic literature review., Head Neck Pathol, 6, S104, 10.1007/s12105-012-0368-1

Ibieta-Zarco, 2012, Frequency and genotype distribution of multiple human papillomavirus infections in cancer of the head and neck in a Mexican population., Oral Surg Oral Med Oral Pathol Oral Radiol, 114, 350, 10.1016/j.oooo.2012.05.003

Herrero, 2003, Human papillomavirus and oral cancer: the International Agency for Research on Cancer multicenter study., J Natl Cancer Inst, 95, 1772, 10.1093/jnci/djg107

Gillison, 2000, Evidence for a causal association between human papillomavirus and a subset of head and neck cancers., J Natl Cancer Inst, 92, 709, 10.1093/jnci/92.9.709

Chakravarthy, 2016, Human papillomavirus drives tumor development throughout the head and neck: improved prognosis is associated with an immune response largely restricted to the oropharynx., J Clin Oncol, 34, 4132, 10.1200/JCO.2016.68.2955

Raval, 2009, Using the NCDB for cancer care improvement: an introduction to available quality assessment tools., J Surg Oncol, 99, 488, 10.1002/jso.v99:8

Cancer Genome Atlas Network, 2015, Comprehensive genomic characterization of head and neck squamous cell carcinomas., Nature, 517, 576, 10.1038/nature14129

Parfenov, 2014, Characterization of HPV and host genome interactions in primary head and neck cancers., Proc Natl Acad Sci U S A, 111, 15544, 10.1073/pnas.1416074111

Hajek, 2017, TRAF3/CYLD mutations identify a distinct subset of human papillomavirus-associated head and neck squamous cell carcinoma., Cancer, 123, 1778, 10.1002/cncr.v123.10

Koneva, 2017, HPV integration in HNSCC correlates with survival outcomes, immune response signatures, and candidate drivers., Mol Cancer Res, 16, 90, 10.1158/1541-7786.MCR-17-0153

D’Souza, 2009, Oral sexual behaviors associated with prevalent oral human papillomavirus infection., J Infect Dis, 199, 1263, 10.1086/599558

Bishop, 2013, Human papillomavirus-related carcinomas of the sinonasal tract., Am J Surg Pathol, 37, 185, 10.1097/PAS.0b013e3182698673

Chung, 2014, p16 protein expression and human papillomavirus status as prognostic biomarkers of nonoropharyngeal head and neck squamous cell carcinoma., J Clin Oncol, 32, 3930, 10.1200/JCO.2013.54.5228

Harris, 2011, Association of p16(INK4a) overexpression with improved outcomes in young patients with squamous cell cancers of the oral tongue., Head Neck, 33, 1622, 10.1002/hed.v33.11

Shaughnessy, 2014, HPV: a factor in organ preservation for locally advanced larynx and hypopharynx cancer?, Am J Otolaryngol, 35, 19, 10.1016/j.amjoto.2013.08.006

Sivars, 2016, Human papillomavirus is a favourable prognostic factor in cancer of unknown primary in the head and neck region and in hypopharyngeal cancer., Mol Clin Oncol, 5, 671, 10.3892/mco.2016.1050

Fakhry, 2017, The prognostic role of sex, race, and human papillomavirus in oropharyngeal and nonoropharyngeal head and neck squamous cell cancer., Cancer, 123, 1566, 10.1002/cncr.v123.9

Lassen, 2014, Impact of HPV-associated p16-expression on radiotherapy outcome in advanced oropharynx and non-oropharynx cancer., Radiother Oncol, 113, 310, 10.1016/j.radonc.2014.11.032

Ko, 2017, Prognostic implications of human papillomavirus status for patients with non-oropharyngeal head and neck squamous cell carcinomas., J Cancer Res Clin Oncol, 143, 2341, 10.1007/s00432-017-2481-8

Morshed, 2010, Association between human papillomavirus infection and laryngeal squamous cell carcinoma., J Med Virol, 82, 1017, 10.1002/jmv.v82:6

Duray, 2011, High incidence of high-risk HPV in benign and malignant lesions of the larynx., Int J Oncol, 39, 51

Sugiyama, 2007, Human papillomavirus-16 in oral squamous cell carcinoma: clinical correlates and 5-year survival., Br J Oral Maxillofac Surg, 45, 116, 10.1016/j.bjoms.2006.04.012

Dogan, 2014, Human papillomavirus and Epstein-Barr virus in nasopharyngeal carcinoma in a low-incidence population., Head Neck, 36, 511, 10.1002/hed.v36.4

Singhi, 2012, High-risk human papillomavirus in nasopharyngeal carcinoma., Head Neck, 34, 213, 10.1002/hed.v34.2

Stenmark, 2014, Nonendemic HPV-positive nasopharyngeal carcinoma: association with poor prognosis., Int J Radiat Oncol Biol Phys, 88, 580, 10.1016/j.ijrobp.2013.11.246

Boffa, 2017, Using the National Cancer Database for outcomes research: a review., JAMA Oncol, 3, 1722, 10.1001/jamaoncol.2016.6905

American Cancer Society, 2017, Cancer Facts & Figures 2017