Association of HLA DRB1 Allele Profile with Pediatric Autoimmune Liver Disease in India

Mieli-Vergani, 2018, Diagnosis and management of pediatric autoimmune liver disease: ESPGHAN Hepatology Committee position statement, J Pediatr Gastroenterol Nutr, 66, 345, 10.1097/MPG.0000000000001801 Trivedi, 2016, The immunogenetics of autoimmune cholestasis, Clin Liver Dis, 20, 15, 10.1016/j.cld.2015.08.002 Donaldson, 2002, Genetics in autoimmune hepatitis, Semin Liver Dis, 22, 353, 10.1055/s-2002-35705 Czaja, 2006, Clinical and HLA phenotypes of type 1 autoimmune hepatitis in North American patients outside DR3 and DR4, Liver Int, 26, 552, 10.1111/j.1478-3231.2006.01249.x Ferucci, 2014, Autoimmune hepatitis in the Alaska Native population: autoantibody profile and HLA associations, Liver Int, 34, 1241, 10.1111/liv.12372 Teufel, 2006, Genetic association of autoimmune hepatitis and human leucocyte antigen in German patients, World J Gastroenterol, 12, 5513, 10.3748/wjg.v12.i34.5513 Umemura, 2014, Human leukocyte antigen class II haplotypes affect clinical characteristics and progression of type 1 autoimmune hepatitis in Japan, PLoS One, 9, 10.1371/journal.pone.0100565 Oka, 2017, HLA-DRB1 and DQB1 alleles in Japanese type 1 autoimmune hepatitis: the predisposing role of the DR4/DR8 heterozygous genotype, PLoS One, 12, 10.1371/journal.pone.0187325 Duarte-Rey, 2009, HLA class II association with autoimmune hepatitis in Latin America: a meta-analysis, Autoimmun Rev, 8, 325, 10.1016/j.autrev.2008.11.005 Shankarkumar, 2005, Human leukocyte antigen allele associations in type-1 autoimmune hepatitis patients from western India, J Gastroenterol Hepatol, 20, 193, 10.1111/j.1440-1746.2004.03608.x Hassan, 2013, Clinical profile and HLA typing of autoimmune hepatitis from Pakistan, Hepat Mon, 13, 10.5812/hepatmon.13598 Kaur, 2014, HLA DRB1 alleles discriminate the manifestation of autoimmune hepatitis as type 1 or type 2 in North Indian population, J Clin Exp Hepatol, 4, 14, 10.1016/j.jceh.2013.12.002 Junge, 2016, Human leucocyte antigens and pediatric autoimmune liver disease: diagnosis and prognosis, Eur J Pediatr, 175, 527, 10.1007/s00431-015-2662-x Ylinen, 2017, Human leucocyte antigens B∗08, DRB1∗03 and DRB1∗13 are significantly associated with autoimmune liver and biliary diseases in Finnish children, Acta Paediatr, 106, 322, 10.1111/apa.13641 Wang, 2014, Autoantibody and human leukocyte antigen profiles in children with autoimmune liver disease and their first-degree relatives, J Pediatr Gastroenterol Nutr, 58, 457, 10.1097/MPG.0000000000000245 Nunes, 2019, HLA-DRB1 gene polymorphisms in pediatric patients with type 1 autoimmune hepatitis and type 1 autoimmune hepatitis overlap syndrome with autoimmune cholangitis, Arq Gastroenterol, 56, 146, 10.1590/s0004-2803.201900000-29 Pando, 1999, Pediatric and adult forms of type I autoimmune hepatitis in Argentina: evidence for differential genetic predisposition, Hepatology, 30, 1374, 10.1002/hep.510300611 Bittencourt, 1999, Genetic heterogeneity in susceptibility to autoimmune hepatitis types 1 and 2, Am J Gastroenterol, 94, 1906, 10.1111/j.1572-0241.1999.01229.x Ma, 2021, Human leukocyte antigen profile predicts severity of autoimmune liver disease in children of European Ancestry, Hepatology, 74, 2032, 10.1002/hep.31893 Elfaramawy, 2010, HLA-DRB1 as a risk factor in children with autoimmune hepatitis and its relation to hepatitis A infection, Ital J Pediatr, 36, 73, 10.1186/1824-7288-36-73 Umemura, 2015, Genetic factors affect the etiology, clinical characteristics and outcome of autoimmune hepatitis, Clin J Gastroenterol, 8, 360, 10.1007/s12328-015-0620-9 Czaja, 2008, Genetic factors affecting the occurrence, clinical phenotype, and outcome of autoimmune hepatitis, Clin Gastroenterol Hepatol, 6, 379, 10.1016/j.cgh.2007.12.048 van Gerven, 2015, HLA-DRB1∗03:01 and HLA-DRB1∗04:01 modify the presentation and outcome in autoimmune hepatitis type-1, Gene Immun, 16, 247, 10.1038/gene.2014.82 Hennes, 2008, Simplified criteria for the diagnosis of autoimmune hepatitis, Hepatology, 48, 169, 10.1002/hep.22322 Alvarez, 1999, International Autoimmune Hepatitis Group Report: review of criteria for diagnosis of autoimmune hepatitis, J Hepatol, 31, 929, 10.1016/S0168-8278(99)80297-9 Deneau, 2017, The natural history of primary sclerosing cholangitis in 781 children: a multicenter, international collaboration, Hepatology, 66, 518, 10.1002/hep.29204 Mack, 2020, Diagnosis and management of autoimmune hepatitis in adults and children: 2019 practice guidance and Guidelines from the American association for the study of liver diseases, Hepatology, 72, 671, 10.1002/hep.31065 Sood, 2018, Spectrum of pediatric autoimmune liver disease and validation of its diagnostic scores in Indian children, J Pediatr Gastroenterol Nutr, 67, e65, 10.1097/MPG.0000000000002050 Khedr, 2022, Seronegative autoimmune hepatitis in children : a real diagnostic challenge, Wien Klin Wochenschr, 134, 195, 10.1007/s00508-021-01907-x Islek, 2021, Seronegative autoimmune hepatitis in children: a single-center experience, Acta Gastroenterol Belg, 84, 305, 10.51821/84.2.305 Kumar, 2021, Autoimmune sclerosing cholangitis in children: a prospective case-control study, Pediatr Gastroenterol Hepatol Nutr, 24, 154, 10.5223/pghn.2021.24.2.154