Association between the CYP2C9 polymorphism and the drug metabolism phenotype

Clinical Chemistry and Laboratory Medicine - Tập 42 Số 1 - 2004
Elizabeta Topić1, Mario Štefanović, Marina Samardžija
1Clinical Institute of Chemistry, School of Medicine, Sestre milosrdnice University Hospital, Zagreb, Croatia.

Tóm tắt

Abstract

CYP2C9, an isoform of the cytochrome P450 enzyme, is involved in the metabolism of most of the drugs of choice for the treatment of thromboembolic disorders. Functional polymorphism is associated with two variant alleles (alleles

Từ khóa


Tài liệu tham khảo

10.1001/jama.279.15.1200

10.1016/S0140-6736(00)03167-6

Meyer UA, 2000, New York: McGrawHill, 1179

10.1097/00008571-200204000-00010

10.1097/00008571-199610000-00007

10.1097/00008571-199608000-00007

10.1097/00008571-199702000-00007

10.1097/00008571-200002000-00011

10.1046/j.0306-5251.2001.01499.x

10.1016/S0140-6736(98)04474-2

10.1097/00008571-200106000-00002

Topić E, 1991, Eur J Clin Chem Clin Biochem, 29, 327

10.1097/00008571-199710000-00011

10.1006/bbrc.1998.9992

10.1378/chest.114.5_Supplement.445S

Taube J, 2000, Blood, 96, 1816, 10.1182/blood.V96.5.1816

10.1046/j.0306-5251.2001.01460.x

10.1007/s002280100264

10.1046/j.1365-2125.1999.00012.x

Margaglione M, 2000, Thromb Haemost, 84, 775, 10.1055/s-0037-1614114

10.1016/S1072-7515(01)01163-2

10.1097/00008571-199710000-00004

10.1016/S0140-6736(05)76918-X

10.1001/archinte.153.13.1557

Thông tin
Thông tin xuất bản

Clinical Chemistry and Laboratory Medicine

Tập 42 Số 1

Thông tin tác giả