Association between occupational exposure to power frequency electromagnetic fields and amyotrophic lateral sclerosis: A review

American Journal of Industrial Medicine - Tập 43 Số 2 - Trang 212-220 - 2003
Chung‐Yi Li1, Fung‐Chang Sung2
1Department of Public Health, College of Medicine, Fu-Jen Catholic University, Taipei Hsien, Taiwan Republic of China
2Graduate Institute of Environmental Health, College of Public Health, National Taiwan University, Taipei, Taiwan Republic of China

Tóm tắt

AbstractBackgroundFor the past two decades, there has been concern over electromagnetic exposure and human health. While most research has focused on cancer and reproductive outcomes, there is interest in the relationship between electromagnetic fields (EMF) and neurodegenerative diseases.MethodsWe review epidemiological findings and evidence regarding the association between occupational exposure to power frequency EMFs and amyotrophic lateral sclerosis (ALS). Medline was searched for citations related to occupational hazards and ALS, literature reviews and epidemiological evaluations.ResultsNine out of the ten epidemiological studies that have been conducted on the risk of ALS in relation to occupational exposure to EMF show moderate to strong relative risk estimates that supported a link between them. Although data from these studies was consistent, the causal inference to a link between EMF exposure and ALS is restricted mainly due to the lack of direct information on EMF exposure and incomplete consideration of the other potential risk factors for ALS at workplaces. For instance, electric shock, in particular, is more common in electrical occupations than in any other occupations.ConclusionsThis review concludes that further studies should consider investigating the separate effect of EMF exposure and electrical shocks to make more specific interpretations. On‐site measurements of EMF should be conducted to include information on EMF exposure from residences as well as workplaces to improve exposure assessment. Am. J. Ind. Med. 43: 212–220, 2003. © 2003 Wiley‐Liss, Inc.

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Tài liệu tham khảo

10.1212/WNL.17.10.1011

Conradi S, 1982, Motor neuron disease and toxic metals, Adv Neurol, 36, 201

10.1159/000110288

10.1002/(SICI)1521-186X(1997)18:1<28::AID-BEM6>3.0.CO;2-7

10.1093/oxfordjournals.aje.a114308

Escriba Aguir V, 1991, Validity of the occupational history assessed by interview, Gac Sanit, 5, 156

10.1111/j.1600-0404.1987.tb07909.x

10.1136/jnnp.46.11.1041

Gerstman BB, 1998, Epidemiology kept simple—an introduction to classic and modern epidemiology, 128p

10.1111/j.1600-0404.1991.tb03970.x

Gunnarsson LG, 1992, A case‐control study of motor neuro disease: Its relation to heritability, and occupational exposures, particularly to solvents, Br J Ind Med, 149, 791

Haenszel W, 1962, Lung cancer mortality as related to residence and smoking histories, J Natl Cancer Inst, 28, 647

Haynal A, 1964, Zusammenhang der amyotrophischen Lateralsklerose mit gehauften Elektrotraumata, Confinia Neurologica, 24, 189, 10.1159/000104117

10.1002/(SICI)1097-0274(199711)32:5<557::AID-AJIM19>3.0.CO;2-1

10.1093/oxfordjournals.aje.a009654

10.1177/216507999704500205

10.2486/indhealth.38.413

10.1093/oxfordjournals.aje.a009070

10.1093/oxfordjournals.aje.a113161

10.1056/NEJM198207223070412

10.1016/S0733-8619(18)30934-4

10.1159/000110279

10.1097/00001648-199807000-00009

10.1080/00039899809605691

10.1002/ajim.4700140203

Schaffer CB, 1981, Neuropathy of central nerve system behavior disorders

10.2105/AJPH.86.9.1281

Semple S, 1998, Factors influencing personal magnetic field exposure: Preliminary results for utility and office workers, Ann Occup Hyg, 42, 167, 10.1016/S0003-4878(98)00017-9

10.1001/archneur.1996.00550080044011

Törnqvist S, 1991, Incidence of leukemia and brain tumors in some “electrical occupations”, Br J Ind Med, 48, 597

10.1002/bem.2250090211

10.1002/bem.2250070213