Association between exogenous testosterone and cardiovascular events: an overview of systematic reviews
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Baillargeon, 2015, Screening and monitoring in men prescribed testosterone therapy in the US, 2001–2010, Public Health Rep, 130, 143, 10.1177/003335491513000207
Baillargeon, 2013, Trends in androgen prescribing in the United States, 2001 to 2011, JAMA Intern Med, 173, 1465, 10.1001/jamainternmed.2013.6895
Basaria, 2010, Adverse events associated with testosterone administration, N Engl J Med, 363, 109, 10.1056/NEJMoa1000485
Vigen, 2013, Association of testosterone therapy with mortality, myocardial infarction, and stroke in men with low testosterone levels, JAMA, 310, 1829, 10.1001/jama.2013.280386
Finkle, 2014, Increased risk of non-fatal myocardial infarction following testosterone therapy prescription in men, PLoS One, 9, e85805, 10.1371/journal.pone.0085805
Shores, 2012, Testosterone treatment and mortality in men with low testosterone levels, J Clin Endocrinol Metab, 97, 2050, 10.1210/jc.2011-2591
Baillargeon, 2014, Risk of myocardial infarction in older men receiving testosterone therapy, Ann Pharmacother, 48, 1138, 10.1177/1060028014539918
Menke, 2010, Sex steroid hormone concentrations and risk of death in US men, Am J Epidemiol, 171, 583, 10.1093/aje/kwp415
Khaw, 2007, Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men: European prospective investigation into cancer in Norfolk (EPIC-Norfolk) prospective population study, Circulation, 116, 2694, 10.1161/CIRCULATIONAHA.107.719005
Laughlin, 2008, Low serum testosterone and mortality in older men, J Clin Endocrinol Metab, 93, 68, 10.1210/jc.2007-1792
Calof, 2005, Adverse events associated with testosterone replacement in middle-aged and older men: a meta-analysis of randomized, placebo-controlled trials, J Gerontol A Biol Sci Med Sci, 60, 1451, 10.1093/gerona/60.11.1451
Haddad, 2007, Testosterone and cardiovascular risk in men: a systematic review and meta-analysis of randomized placebo-controlled trials, Mayo Clin Proc, 82, 29, 10.1016/S0025-6196(11)60964-6
Fernandez-Balsells, 2010, Adverse effects of testosterone therapy in adult men: a systematic review and meta-analysis, J Clin Endocrinol Metab, 95, 2560, 10.1210/jc.2009-2575
Xu, 2013, Testosterone therapy and cardiovascular events among men: a systematic review and meta-analysis of placebo-controlled randomized trials, BMC Med, 11, 108, 10.1186/1741-7015-11-108
Borst, 2014, Cardiovascular risks and elevation of serum DHT vary by route of testosterone administration: a systematic review and meta-analysis, BMC Med, 12, 211, 10.1186/s12916-014-0211-5
Corona, 2014, Cardiovascular risk associated with testosterone-boosting medications: a systematic review and meta-analysis, Expert Opin Drug Saf, 13, 1327, 10.1517/14740338.2014.950653
Albert, 2016, Testosterone therapy, association with age, initiation and mode of therapy with cardiovascular events: a systematic review, Clin Endocrinol, 85, 436, 10.1111/cen.13084
Becker, 2008, Overviews of reviews, 22.1.1
Smith, 2011, Methodology in conducting a systematic review of systematic reviews of healthcare interventions, BMC Med Res Methodol, 11, 1, 10.1186/1471-2288-11-15
Shea, 2007, Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews, BMC Med Res Methodol, 7, 1, 10.1186/1471-2288-7-10
Shea, 2009, AMSTAR is a reliable and valid measurement tool to assess the methodological quality of systematic reviews, J Clin Epidemiol, 62, 1013, 10.1016/j.jclinepi.2008.10.009
Shea, 2007, External validation of a measurement tool to assess systematic reviews (AMSTAR), PLoS One, 2, e1350, 10.1371/journal.pone.0001350
Suebnukarn, 2010, A systematic evaluation of the quality of meta-analyses in endodontics, J Endod, 36, 602, 10.1016/j.joen.2009.12.019
Seo, 2012, Quality assessment of systematic reviews or meta-analyses of nursing interventions conducted by Korean reviewers, BMC Med Res Methodol, 12, 129, 10.1186/1471-2288-12-129
Bradburn, 2007, Much ado about nothing: a comparison of the performance of meta-analytical methods with rare events, Stat Med, 26, 53, 10.1002/sim.2528
Stoto, 2015, Drug safety meta-analysis: promises and pitfalls, Drug Saf, 38, 233, 10.1007/s40264-015-0268-x
Higgins JPT, Deeks JJ, Altman DG. Special topics in statistics. In: Higgins JPT, Green S, eds. Cochrane handbook for systematic reviews of interventions, version 5.1.0 (updated March, 2011). The Cochrane Collaboration, 2011: 16.9.5.
Rosner, 2010, Hypothesis testing: categorical data—estimation of sample size and power for comparing two binomial proportions, 381
1986, Testosterone treatment of men with alcoholic cirrhosis: a double blind study, Hepatology, 6, 807, 10.1002/hep.1840060502
Marin, 1992, The effects of testosterone treatment on body composition and metabolism in middle-aged obese men, Int J Obes Relat Metab Disord, 16, 991
Tenover, 1992, Effects of testosterone supplementatio in the aging male, J Clin Endocrinol Metab, 75, 1092
Morley, 1993, Effects of testosterone replacement therapy in old hypogonadal males: a preliminary study, J Am Geriatr Soc, 41, 149, 10.1111/j.1532-5415.1993.tb02049.x
Drinka, 1995, Polycythemia as a complication of testosterone replacement therapy in nursing home men with low testosterone levels, J Am Geriatr Soc, 43, 899, 10.1111/j.1532-5415.1995.tb05534.x
Hall, 1996, A randomized trial of testosterone therapy in males with rheumatoid arthritis, Br J Rheumatol, 35, 568, 10.1093/rheumatology/35.6.568
Reid, 1996, Testosterone therapy in glucocorticoid-treated men, Arch Intern Med, 156, 1173, 10.1001/archinte.1996.00440100065008
Sih, 1997, Testosterone replacement in older hypogonadal men: a 12-month randomized controlled trial, J Clin Endocrinol Metab, 82, 1661, 10.1210/jcem.82.6.3988
English, 2000, Low-dose transdermal testosterone therapy improves angina threshold in men with chronic stable angina: a randomized, double-blind, placebo-controlled study, Circulation, 102, 1906, 10.1161/01.CIR.102.16.1906
Snyder, 2001, Effect of transdermal testosterone treatment on serum lipid and apolipoprotein levels in men more than 65 years of age, Am J Med, 111, 255, 10.1016/S0002-9343(01)00813-0
Simon, 2001, Androgen therapy improves insulin sensitivity and decreases leptin level in healthy adult men with low plasma total testosterone: a 3-month randomized placebo-controlled trial, Diabetes Care, 24, 2149, 10.2337/diacare.24.12.2149
Seidman, 2001, Testosterone replacement therapy for hypogonadal men with major depressive disorder: a randomized, placebo-controlled clinical trial, J Clin Psychiatry, 62, 406, 10.4088/JCP.v62n0602
Münzer, 2001, Effects of GH and/or sex steroid administration on abdominal subcutaneous and visceral fat in healthy aged women and men, J Clin Endocrinol Metab, 86, 3604, 10.1210/jc.86.8.3604
Kenny, 2002, Effects of transdermal testosterone on lipids and vascular reactivity in older men with low bioavailable testosterone levels, J Gerontol A Biol Sci Med Sci, 57, M460, 10.1093/gerona/57.7.M460
Amory, 2002, Preoperative supraphysiological testosterone in older men undergoing knee replacement surgery, J Am Geriatr Soc, 50, 1698, 10.1046/j.1532-5415.2002.50462.x
Ferrando, 2003, Differential anabolic effects of testosterone and amino acid feeding in older men, J Clin Endocrinol Metab, 88, 358, 10.1210/jc.2002-021041
Boyanov, 2003, Testosterone supplementation in men with type 2 diabetes, visceral obesity and partial androgen deficiency, Aging Male, 6, 1, 10.1080/tam.6.1.1.7
Wittert, 2003, Oral testosterone supplementation increases muscle and decreases fat mass in healthy elderly males with low-normal gonadal status, J Gerontol A Biol Sci Med Sci, 58, 618, 10.1093/gerona/58.7.M618
Steidle, 2003, AA2500 testosterone gel normalizes androgen levels in aging males with improvements in body composition and sexual function, J Clin Endocrinol Metab, 88, 2673, 10.1210/jc.2002-021058
Crawford, 2003, Randomized placebo-controlled trial of androgen effects on muscle and bone in men requiring long-term systemic glucocorticoid treatment, J Clin Endocrinol Metab, 88, 3167, 10.1210/jc.2002-021827
Amory, 2004, Exogenous testosterone or testosterone with finasteride increases bone mineral density in older men with low serum testosterone, J Clin Endocrinol Metab, 89, 503, 10.1210/jc.2003-031110
Kenny, 2004, Effects of testosterone on behavior, depression, and cognitive function in older men with mild cognitive loss, J Gerontol A Biol Sci Med Sci, 59, 75, 10.1093/gerona/59.1.M75
Svartberg, 2004, Testosterone treatment improves body composition and sexual function in men with COPD, in a 6-month randomized controlled trial, Respir Med, 98, 906, 10.1016/j.rmed.2004.02.015
Brockenbrough, 2006, Transdermal androgen therapy to augment EPO in the treatment of anemia of chronic renal disease, Am J Kidney Dis, 47, 251, 10.1053/j.ajkd.2005.10.022
Malkin, 2006, Testosterone therapy in men with moderate severity heart failure: a double-blind randomized placebo controlled trial, Eur Heart J, 27, 57, 10.1093/eurheartj/ehi443
Merza, 2006, Double-blind placebo-controlled study of testosterone patch therapy on bone turnover in men with borderline hypogonadism, Int J Androl, 29, 381, 10.1111/j.1365-2605.2005.00612.x
Nair, 2006, DHEA in elderly women and DHEA or testosterone in elderly men, N Engl J Med, 355, 1647, 10.1056/NEJMoa054629
Emmelot-Vonk, 2008, Effect of testosterone supplementation on functional mobility, cognition and other parameters in older men: a randomized controlled trial, JAMA, 299, 39, 10.1001/jama.2007.51
Svartberg, 2008, Testosterone treatment in elderly men with subnormal testosterone levels improves body composition and BMD in the hip, Int J Impotence Res, 20, 378, 10.1038/ijir.2008.19
Caminiti, 2009, Effect of long-acting testosterone treatment on functional exercise capacity, skeletal muscle performance, insulin resistance, and baroreflex sensitivity in elderly patients with chronic heart failure a double-blind, placebo-controlled, randomized study, J Am Coll Cardiol, 54, 919, 10.1016/j.jacc.2009.04.078
Chapman, 2009, Effect of testosterone and a nutritional supplement, alone and in combination, on hospital admissions in undernourished older men and women, Am J Clin Nutr, 89, 880, 10.3945/ajcn.2008.26538
Legros, 2009, Oral testosterone replacement in symptomatic late-onset hypogonadism: effects on rating scales and general safety in a randomized, placebo-controlled study, Eur J Endocrinol, 160, 821, 10.1530/EJE-08-0634
Mathur, 2009, Long-term benefits of testosterone replacement therapy on angina threshold and atheroma in men, Eur J Endocrinol, 161, 443, 10.1530/EJE-09-0092
Shores, 2009, A randomized, double-blind, placebo-controlled study of testosterone treatment in hypogonadal older men with subthreshold depression (dysthymia or minor depression), J Clin Psychiatry, 70, 1009, 10.4088/JCP.08m04478
Aversa, 2010, Effects of testosterone undecanoate on cardiovascular risk factors and atherosclerosis in middle-aged men with late-onset hypogonadism and metabolic syndrome: results from a 24-month, randomized, double-blind, placebo-controlled study, J Sex Med, 7, 3495, 10.1111/j.1743-6109.2010.01931.x
Cornoldi, 2010, Effects of chronic testosterone administration on myocardial ischemia, lipid metabolism and insulin resistance in elderly male diabetic patients with coronary artery disease, Int J Cardiol, 142, 50, 10.1016/j.ijcard.2008.12.107
Srinivas-Shankar, 2010, Effects of testosterone on muscle strength, physical function, body composition, and quality of life in intermediate-frail and frail elderly men: a randomized, double-blind, placebo-controlled study, J Clin Endocrinol Metab, 95, 639, 10.1210/jc.2009-1251
Kalinchenko, 2010, Effects of testosterone supplementation on markers of the metabolic syndrome and inflammation in hypogonadal men with the metabolic syndrome: the double-blinded placebo-controlled Moscow study, Clin Endocrinol, 73, 602, 10.1111/j.1365-2265.2010.03845.x
Kenny, 2010, Effects of transdermal testosterone on bone and muscle in older men with low bioavailable testosterone levels, low bone mass, and physical frailty, J Am Geriatr Soc, 58, 1134, 10.1111/j.1532-5415.2010.02865.x
Jones, 2011, Testosterone replacement in hypogonadal men with type 2 diabetes and/or metabolic syndrome (the TIMES2 study), Diabetes Care, 34, 828, 10.2337/dc10-1233
Ho, 2012, A randomized, double-blind, placebocontrolled trial on the effect of longacting testosterone treatment as assessed by the Aging Male Symptoms scale, BJU Int, 110, 260, 10.1111/j.1464-410X.2011.10755.x
Kaufman, 2011, Efficacy and safety study of 1·62% testosterone gel for the treatment of hypogonadal men, J Sex Med, 8, 2079, 10.1111/j.1743-6109.2011.02265.x
Sheffield-Moore, 2011, A randomized pilot study of monthly cycled testosterone replacement or continuous testosterone replacement versus placebo in older men, J Clin Endocrinol Metab, 96, E1831, 10.1210/jc.2011-1262
Hoyos, 2012, Body compositional and cardiometabolic effects of testosterone therapy in obese men with severe obstructive sleep apnoea: a randomised placebo-controlled trial, Eur J Endocrinol, 167, 531, 10.1530/EJE-12-0525
Spitzer, 2012, Effect of testosterone replacement on response to sildenafil citrate in men with erectile dysfunction: a parallel, randomized trial, Ann Intern Med, 157, 681, 10.7326/0003-4819-157-10-201211200-00004
Glintborg, 2013, Strength training and testosterone treatment have opposing effects on migration inhibitor factor levels in ageing men, Mediators Inflamm, 2013, 539156, 10.1155/2013/539156
Hildreth, 2013, Effects of testosterone and progressive resistance exercise in healthy, highly functioning older men with low-normal testosterone levels, J Clin Endocrinol Metab, 98, 1891, 10.1210/jc.2012-3695
Hackett, 2013, Testosterone replacement therapy with long-acting testosterone undecanoate improves sexual function and quality-of-life parameters vs placebo in a population of men with type 2 diabetes, J Sex Med, 10, 1612, 10.1111/jsm.12146
Tan, 2013, Efficacy and safety of long-acting intramuscular testosterone undecanoate in aging men: a randomised controlled study, BJU Int, 111, 1130, 10.1111/bju.12037
Borst, 2014, Musculoskeletal and prostate effects of combined testosterone and finasteride administration in older hypogonadal men: a randomized, controlled trial, Am J Physiol Endocrinol Metab, 306, E433, 10.1152/ajpendo.00592.2013
Gianatti, 2014, Effect of testosterone treatment on constitutional and sexual symptoms in men with type 2 diabetes in a randomized, placebo-controlled clinical trial, J Clin Endocrinol Metab, 99, 3821, 10.1210/jc.2014-1872
Basaria, 2015, Effects of testosterone administration for 3 years on subclinical atherosclerosis progression in older men with low or low-normal testosterone levels: a randomized clinical trial, JAMA, 314, 570, 10.1001/jama.2015.8881
Snyder, 2016, Effects of testosterone treatment in older men, N Engl J Med, 374, 611, 10.1056/NEJMoa1506119
Rauch, 2015, Opportunities and challenges of clinical trials in cardiology using composite primary endpoints, World J Cardiol, 7, 1, 10.4330/wjc.v7.i1.1
Ferreira-Gonzalez, 2007, Problems with use of composite end points in cardiovascular trials: systematic review of randomised controlled trials, BMJ, 334, 786, 10.1136/bmj.39136.682083.AE
Montori, 2005, Validity of composite end points in clinical trials, BMJ, 330, 594, 10.1136/bmj.330.7491.594
Herring, 2013, Testosterone and the cardiovascular system: a comprehensive review of the basic science literature, J Am Heart Assoc, 2, e000271, 10.1161/JAHA.113.000271
Gotzsche, 2007, Data extraction errors in meta-analyses that use standardized mean differences, JAMA, 298, 430
DerSimonian, 2007, Random-effects model for meta-analysis of clinical trials: an update, Contemp Clin Trials, 28, 105, 10.1016/j.cct.2006.04.004
DerSimonian, 1986, Meta-analysis in clinical trials, Control Clin Trials, 7, 177, 10.1016/0197-2456(86)90046-2
Shuster, 2010, Empirical vs natural weighting in random effects meta-analysis, Stat Med, 29, 1259, 10.1002/sim.3607
McAuley, 2000, Does the inclusion of grey literature influence estimates of intervention effectiveness reported in meta-analyses?, Lancet, 356, 1228, 10.1016/S0140-6736(00)02786-0
Moreno, 2009, Assessment of regression-based methods to adjust for publication bias through a comprehensive simulation study, BMC Med Res Methodol, 9, 2, 10.1186/1471-2288-9-2
Ahmed, 2012, Assessment of publication bias, selection bias, and unavailable data in meta-analyses using individual participant data: a database survey, BMJ, 344, d7762, 10.1136/bmj.d7762
Muraleedharan, 2013, Testosterone deficiency is associated with increased risk of mortality and testosterone replacement improves survival in men with type 2 diabetes, Eur J Endocrinol, 169, 725, 10.1530/EJE-13-0321
Wallis, 2016, Survival and cardiovascular events in men treated with testosterone replacement therapy: an intention-to-treat observational cohort study, Lancet Diabetes Endocrinol, 4, 498, 10.1016/S2213-8587(16)00112-1
Sharma, 2015, Normalization of testosterone level is associated with reduced incidence of myocardial infarction and mortality in men, Eur Heart J, 36, 2706, 10.1093/eurheartj/ehv346
Anderson, 2016, Impact of testosterone replacement therapy on myocardial infarction, stroke, and death in men with low testosterone concentrations in an integrated health care system, Am J Cardiol, 117, 794, 10.1016/j.amjcard.2015.11.063
Smith, 2003, ‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?, Int J Epidemiol, 32, 1, 10.1093/ije/dyg070
Smith, 2014, Mendelian randomization: genetic anchors for causal inference in epidemiological studies, Hum Mol Genet, 23, R89, 10.1093/hmg/ddu328
Riley, 2010, Meta-analysis of individual participant data: rationale, conduct, and reporting, BMJ, 340, c221, 10.1136/bmj.c221
Lago, 2007, Congestive heart failure and cardiovascular death in patients with prediabetes and type 2 diabetes given thiazolidinediones: a meta-analysis of randomised clinical trials, Lancet, 370, 1129, 10.1016/S0140-6736(07)61514-1
Graham, 2005, Risk of acute myocardial infarction and sudden cardiac death in patients treated with cyclo-oxygenase 2 selective and non-selective non-steroidal anti-inflammatory drugs: nested case-control study, Lancet, 365, 475, 10.1016/S0140-6736(05)70270-1
McGettigan, 2006, Cardiovascular risk and inhibition of cyclooxygenase: a systematic review of the observational studies of selective and nonselective inhibitors of cyclooxygenase 2, JAMA, 296, 1633, 10.1001/jama.296.13.jrv60011
Stone, 2009, Risk of suicidality in clinical trials of antidepressants in adults: analysis of proprietary data submitted to US Food and Drug Administration, BMJ, 339, b2880, 10.1136/bmj.b2880