Assessment of the effects of skin microneedling as adjuvant therapy for facial melasma: a pilot study

Handel AC, Miot LD, Miot HA. Melasma: a clinical and epidemiological review. An Bras Dermatol. 2014;89(5):771–82. doi:10.1590/abd1806-4841.20143063 .

Sheth VM, Pandya AG. Melasma: a comprehensive update: part I. J Am Acad Dermatol. 2011;65(4):689-697. doi: doi:10.1016/j.jaad.2010.12.046 .

D'Elia MP, Brandao MC, de Andrade Ramos BR, da Silva MG, Miot LD, Dos Santos SE, et al. African ancestry is associated with facial melasma in women: a cross-sectional study. BMC Med Genet. 2017;18(1):17. doi:10.1186/s12881-017-0378-7.

Maranzatto CF, Miot HA, Miot LD, Meneguin S. Psychometrican analysis and dimensional structure of the Brazilian version of melasma quality of life scale (MELASQoL-BP). An Bras Dermatol. 2016;91(4):422–8. doi:10.1590/abd1806-4841.20165014 .

Ishiy PS, Silva LR, Penha MA, Handel AC, Miot HA. Skin diseases reported by workers from UNESP campus at Rubiao Jr, Botucatu-SP (Brazil). An Bras Dermatol 2014;89(3):529-531. doi:10.1590/abd1806-4841.20142875.

Miot LD, Miot HA, Polettini J, Silva MG, Marques ME. Morphologic changes and the expression of alpha-melanocyte stimulating hormone and melanocortin-1 receptor in melasma lesions: a comparative study. Am J Dermatopathol. 2010;32(7):676–82. doi:10.1097/DAD.0b013e3181cd4396.

Brianezi G, Handel AC, Schmitt JV, Miot LD, Miot HA. Changes in nuclear morphology and chromatin texture of basal keratinocytes in melasma. J Eur Acad Dermatol Venereol. 2015;29(4):809–12. doi:10.1111/jdv.12453.

Lee AY. Recent progress in melasma pathogenesis. Pigment Cell Melanoma Res. 2015;28(6):648–60. doi:10.1111/pcmr.12404.

Doddaballapur S. Microneedling with dermaroller. J Cutan Aesthet Surg. 2009;2(2):110–1. doi:10.4103/0974-2077.58529.

Lima Ede A, Lima Mde A, D. T. Microneedling: experimental study and classification of the resulting injury. Surg Cosm Dermatol 2013;5(2):110-114.

Hou A, Cohen B, Haimovic A, Elbuluk N. Microneedling: A Comprehensive Review. Dermatol Surg. 2017;43(3):321–39. doi:10.1097/DSS.0000000000000924 .

Cohen BE, Elbuluk N. Microneedling in skin of color: a review of uses and efficacy. J Am Acad Dermatol. 2016;74(2):348–55. doi:10.1016/j.jaad.2015.09.024 .

Lima Ede A. Microneedling in facial recalcitrant melasma: report of a series of 22 cases. An Bras Dermatol. 2015;90(6):919–21. doi:10.1590/abd1806-4841.20154748 .

Takiwaki H, Miyamoto H, Ahsan K. A simple method to estimate CIE-L*a*b* values of the skin from its videomicroscopic image. Skin Res Technol. 1997;3(1):42–4. doi:10.1111/j.1600-0846.1997.tb00158.x .

Pandya AG, Hynan LS, Bhore R, Riley FC, Guevara IL, Grimes P, et al. Reliability assessment and validation of the Melasma area and severity index (MASI) and a new modified MASI scoring method. J Am Acad Dermatol. 2011;64(1):78–83. doi:10.1016/j.jaad.2009.10.051 .

Cestari TF, Balkrishann R, Weber MB, Prati C, Menegon DB, Mazzott NG, et al. Translation and cultural adaptation to Portuguese of a quality of life questionnaire for patients with melasma. Med Cutan Iber Lat Am. 2006;34:270–4.

Miot HA. Assessing normality of data in clinical and experimental trials. J Vasc Bras. 2017;16(2):88–91. doi:10.1590/1677-5449.041117 .

Norman GR, Streiner DL. Biostatistics: the bare essentials. 4th ed. Shelton: PMPH-USA; 2014.

Miot HA. Sample size in clinical and experimental trials. J Vasc Bras. 2011;10(4):275–8. doi:10.1590/S1677-54492011000400001 .

Cestari TF, Hexsel D, Viegas ML, Azulay L, Hassun K, Almeida AR, et al. Validation of a melasma quality of life questionnaire for Brazilian Portuguese language: the MelasQoL-BP study and improvement of QoL of melasma patients after triple combination therapy. Br J Dermatol. 2006;156(Suppl 1):13–20. doi:10.1111/j.1365-2133.2006.07591.x .

Torres-Alvarez B, Mesa-Garza IG, Castanedo-Cazares JP, Fuentes-Ahumada C, Oros-Ovalle C, Navarrete-Solis J, et al. Histochemical and immunohistochemical study in melasma: evidence of damage in the basal membrane. Am J Dermatopathol. 2011;33(3):291–5. doi:10.1097/DAD.0b013e3181ef2d45.

Byun JW, Park IS, Choi GS, Shin J. Role of fibroblast-derived factors in the pathogenesis of melasma. Clin Exp Dermatol. 2016;41(6):601–9. doi:10.1111/ced.12874.

Miot HA, Brianezi G. Morphometric analysis of dermal collagen by color clusters segmentation. An Bras Dermatol. 2010;85(3):361–4. doi:10.1590/S0365-05962010000300010.

Ramaut L, Hoeksema H, Pirayesh A, Stillaert F, Monstrey S. Microneedling: where do we stand now? A systematic review of the literature. J Plast Reconstr Aesthet Surg. 2017 (ahead of print). doi:S1748–6815(17)30250–4.

Alster TS, Graham PM. Microneedling: A Review and Practical Guide. Dermatol Surg. 2017 (ahead of print). doi:10.1097/DSS.0000000000001248 .

Tamega Ade A, Miot HA, Moco NP, Silva MG, Marques ME, Miot LD. Gene and protein expression of oestrogen-beta and progesterone receptors in facial melasma and adjacent healthy skin in women. Int J Cosmet Sci. 2015;37(2):222–8. https://doi.org/10.1111/ics.12186 .

Lee DJ, Park KC, Ortonne JP, Kang HY. Pendulous melanocytes: a characteristic feature of melasma and how it may occur. Br J Dermatol. 2012;166(3):684–6. doi:10.1111/j.1365-2133.2011.10648.x.

Bhawan J, Grimes P, Pandya AG, Keady M, Byers HR, Guevara IL, et al. A histological examination for skin atrophy after 6 months of treatment with fluocinolone acetonide 0.01%, hydroquinone 4%, and tretinoin 0.05% cream. Am J Dermatopathol. 2009;31(8):794–8. https://doi.org/10.1097/DAD.0b013e3181a9070d.

Lev-Tov H, Larsen L, Zackria R, Chahal H, Eisen DB, Sivamani RK. Microneedle-assisted incubation during aminolaevulinic acid photodynamic therapy of actinic keratoses: a randomized controlled evaluator-blind trial. Br J Dermatol. 2017;176(2):543–5. doi:10.1111/bjd.15116.

Sivamani RK, Liepmann D, Maibach HI. Microneedles and transdermal applications. Expert Opin Drug Deliv. 2007;4(1):19–25. https://doi.org/10.1517/17425247.4.1.19 .

Budamakuntla L, Loganathan E, Suresh DH, Shanmugam S, Suryanarayan S, Dongare A, et al. A randomised, open-label, comparative study of Tranexamic acid microinjections and Tranexamic acid with microneedling in patients with Melasma. J Cutan Aesthet Surg. 2013;6(3):139–43. doi:10.4103/0974-2077.118403 .

Ustuner P, Balevi A, Ozdemir M. A split-face, investigator-blinded comparative study on the efficacy and safety of Q-switched Nd:YAG laser plus microneedling with vitamin C versus Q-switched Nd:YAG laser for the treatment of recalcitrant melasma. J Cosmet Laser Ther. 2017:1–8. doi:10.1080/14764172.2017.1342036 .

Kunachak S, Leelaudomlipi P, Wongwaisayawan S. Dermabrasion: a curative treatment for melasma. Aesthet Plast Surg. 2001;25(2):114–7. doi:10.1007/s002660010107 .

Bonati LM, Epstein GK, Strugar TL. Microneedling in all skin types: a review. J Drugs Dermatol. 2017;16(4):308–13.

Ornelas J, Foolad N, Shi V, Burney W, Sivamani RK. Effect of microneedle pretreatment on topical anesthesia: a randomized clinical trial. JAMA Dermatol. 2016;152(4):476–7. doi:10.1001/jamadermatol.2015.5544 .