Assessing efficacy of antiviral therapy for COVID-19 patients: A case study on remdesivir with bayesian synthesis design and multistate analysis

Journal of the Formosan Medical Association - Tập 120 - Trang S77-S85 - 2021
Sih-Han Liao1,2,3, Chien-Ching Hung4,5, Chiung-Nien Chen6,7, Jui-Yi Yen8, Chen-Yang Hsu1,9, Amy Ming-Fang Yen10, Chi-Ling Chen1,7,11
1Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
2Section of Gastroenterology, Department of Medicine, National Taiwan University Cancer Center, Taipei, Taiwan
3Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
4Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
5Department of Tropical Medicine and Parasitology, National Taiwan University College of Medicine, Taipei, Taiwan
6Center for Functional Image and Interventional Therapy, National Taiwan University, Taipei, Taiwan
7Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan
8Department of Anesthesiology, Taipei Veterans General Hospital, Taipei, Taiwan
9Dachung Hospital, Miaoli, Taiwan
10School of Oral Hygiene, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan
11Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan

Tài liệu tham khảo

Li, 2020, Early transmission dynamics in wuhan, China, of novel coronavirus-infected pneumonia, N Engl J Med, 382, 1199, 10.1056/NEJMoa2001316 Huang, 2020, Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China, Lancet, 395, 497, 10.1016/S0140-6736(20)30183-5 Dong, 2020, An interactive web-based dashboard to track COVID-19 in real time, Lancet Infect Dis, 20, 533, 10.1016/S1473-3099(20)30120-1 Peters, 2020, Transforming ORs into ICUs, N Engl J Med, 382, e52, 10.1056/NEJMc2010853 Phua, 2020, Intensive care management of coronavirus disease 2019 (COVID-19): challenges and recommendations, Lancet Respir Med, 8, 506, 10.1016/S2213-2600(20)30161-2 Ranney, 2020, Critical supply shortages - the need for ventilators and personal protective equipment during the covid-19 pandemic, N Engl J Med, 382, e41, 10.1056/NEJMp2006141 Truog, 2020, The toughest triage - allocating ventilators in a pandemic, N Engl J Med, 382, 1973, 10.1056/NEJMp2005689 Polack, 2020, Safety and efficacy of the BNT162b2 mRNA covid-19 vaccine, N Engl J Med, 383, 2603, 10.1056/NEJMoa2034577 Baden, 2021, Efficacy and safety of the mRNA-1273 SARS-CoV-2 vaccine, N Engl J Med, 384, 403, 10.1056/NEJMoa2035389 Sadoff, 2021, Interim results of a phase 1-2a trial of Ad26.COV2.S covid-19 vaccine, N Engl J Med, 384, 1824, 10.1056/NEJMoa2034201 Voysey, 2021, Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK, Lancet, 397, 99, 10.1016/S0140-6736(20)32661-1 Dagan, 2021, BNT162b2 mRNA covid-19 vaccine in a nationwide mass vaccination setting, N Engl J Med, 384, 1412, 10.1056/NEJMoa2101765 Liu, 2020, Efficacy and safety of antiviral treatment for COVID-19 from evidence in studies of SARS-CoV-2 and other acute viral infections: a systematic review and meta-analysis, CMAJ (Can Med Assoc J), 192, E734, 10.1503/cmaj.200647 Abdelrahman, 2021, Evaluation of the current therapeutic approaches for COVID-19: a systematic review and a meta-analysis, Front Pharmacol, 12, 607408, 10.3389/fphar.2021.607408 Gandhi, 2020, Mild or moderate covid-19, N Engl J Med, 383, 1757, 10.1056/NEJMcp2009249 World Health Organization, 2020 2020, 2020 Grein, 2020, Compassionate use of remdesivir for patients with severe covid-19, N Engl J Med, 382, 2327, 10.1056/NEJMoa2007016 Beigel, 2020, Remdesivir for the treatment of covid-19—preliminary report, N Engl J Med, 383, 993 Beigel, 2020, Remdesivir for the treatment of covid-19 - final report, N Engl J Med, 383, 1813, 10.1056/NEJMoa2007764 Kalil, 2021, Baricitinib plus remdesivir for hospitalized adults with covid-19, N Engl J Med, 384, 795, 10.1056/NEJMoa2031994 Wang, 2020, Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial, Lancet, 395, 1569, 10.1016/S0140-6736(20)31022-9 Abd-Elsalam, 2020, Hydroxychloroquine in the treatment of COVID-19: a multicenter randomized controlled study, Am J Trop Med Hyg, 103, 1635, 10.4269/ajtmh.20-0873 Cao, 2020, A trial of lopinavir-ritonavir in adults hospitalized with severe covid-19, N Engl J Med, 382, 1787, 10.1056/NEJMoa2001282 Cavalcanti, 2020, Hydroxychloroquine with or without azithromycin in mild-to-moderate covid-19, N Engl J Med, 383, 2041, 10.1056/NEJMoa2019014 Chen, 2020, A multicenter, randomized, open-label, controlled trial to evaluate the efficacy and tolerability of hydroxychloroquine and a retrospective study in adult patients with mild to moderate coronavirus disease 2019 (COVID-19), PloS One, 15 Horby, 2020, Effect of hydroxychloroquine in hospitalized patients with covid-19, N Engl J Med, 383, 2030, 10.1056/NEJMoa2022926 Mitjà, 2020, Hydroxychloroquine for early treatment of adults with mild covid-19: a randomized-controlled trial, Clin Infect Dis Omrani, 2020, Randomized double-blinded placebo-controlled trial of hydroxychloroquine with or without azithromycin for virologic cure of non-severe Covid-19, EClinicalMedicine, 29, 100645, 10.1016/j.eclinm.2020.100645 2020, Lopinavir-ritonavir in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial, Lancet, 396, 1345, 10.1016/S0140-6736(20)32013-4 Lamontagne, 2021, A living WHO guideline on drugs to prevent covid-19, BMJ, 372, n526, 10.1136/bmj.n526 Siemieniuk, 2020, A living WHO guideline on drugs for covid-19, BMJ, 370, m3379 Rubin, 2020, FDA approval of remdesivir - a step in the right direction, N Engl J Med, 383, 2598, 10.1056/NEJMp2032369 Gao, 2020, Structure of the RNA-dependent RNA polymerase from COVID-19 virus, Science, 368, 779, 10.1126/science.abb7498 Gordon, 2020, The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus, J Biol Chem, 295, 4773, 10.1074/jbc.AC120.013056 Jorgensen, 2020, Remdesivir: review of pharmacology, pre-clinical data, and emerging clinical experience for COVID-19, Pharmacotherapy, 40, 659, 10.1002/phar.2429 Norrie, 2020, Remdesivir for COVID-19: challenges of underpowered studies, Lancet, 395, 1525, 10.1016/S0140-6736(20)31023-0 McCreary, 2020, Efficacy of remdesivir in COVID-19, J Am Med Assoc, 324, 1041, 10.1001/jama.2020.16337 Cohen, 2020, “A very, very bad look” for remdesivir, Science, 370, 642, 10.1126/science.370.6517.642 Dyer, 2020, Covid-19: remdesivir has little or no impact on survival, WHO trial shows, BMJ, 371 World Health Organization, 2020 Jen, 2021, Evaluating clinical efficacy of antiviral therapy for COVID-19: a surrogate endpoint Approach, Infect Dis Ther, 1 Wu, 2014, Risk assessment of multistate progression of breast tumor with state-dependent genetic and environmental covariates, Risk Anal, 34, 367, 10.1111/risa.12116 Nachega, 2021, Addressing challenges to rolling out COVID-19 vaccines in African countries, Lancet Glob Heal, 9, e746, 10.1016/S2214-109X(21)00097-8 Vergara, 2021, Building public trust: a response to COVID-19 vaccine hesitancy predicament, J Public Health, 10.1093/pubmed/fdaa282 Schaffer DeRoo, 2020, Planning for a COVID-19 vaccination program, J Am Med Assoc, 323, 2458, 10.1001/jama.2020.8711 Dror, 2020, Vaccine hesitancy: the next challenge in the fight against COVID-19, Eur J Epidemiol, 35, 775, 10.1007/s10654-020-00671-y Sabino, 2021, Resurgence of COVID-19 in Manaus, Brazil, despite high seroprevalence, Lancet, 397, 452, 10.1016/S0140-6736(21)00183-5 Ferguson, 2005, Strategies for containing an emerging influenza pandemic in Southeast Asia, Nature, 437, 209, 10.1038/nature04017 Moscona, 2005, Neuraminidase inhibitors for influenza, N Engl J Med, 353, 1363, 10.1056/NEJMra050740