Assessing T lymphocyte function and differentiation by genetically encoded reporter systems
Tài liệu tham khảo
Murphy, 2008
Chudakov, 2010, Fluorescent proteins and their applications in imaging living cells and tissues, Physiol. Rev., 90, 1103, 10.1152/physrev.00038.2009
Ibraheem, 2010, Designs and applications of fluorescent protein-based biosensors, Curr. Opin. Chem. Biol., 14, 30, 10.1016/j.cbpa.2009.09.033
Barnea, 2008, The genetic design of signaling cascades to record receptor activation, Proc. Natl. Acad. Sci. U.S.A., 105, 64, 10.1073/pnas.0710487105
Inagaki, 2012, Visualizing neuromodulation in vivo: TANGO-mapping of dopamine signaling reveals appetite control of sugar sensing, Cell, 148, 583, 10.1016/j.cell.2011.12.022
Kono, 2014, Sphingosine-1-phosphate receptor 1 reporter mice reveal receptor activation sites in vivo, J. Clin. Invest., 124, 2076, 10.1172/JCI71194
Kerppola, 2008, Bimolecular fluorescence complementation (BiFC) analysis as a probe of protein interactions in living cells, Annu. Rev. Biophys., 37, 465, 10.1146/annurev.biophys.37.032807.125842
Yu, 2006, Probing gene expression in live cells, one protein molecule at a time, Science, 311, 1600, 10.1126/science.1119623
Lemay, 2008, The role of the tight-turn, broken hydrogen bonding, Glu222 and Arg96 in the post-translational green fluorescent protein chromophore formation, Chem. Phys., 348, 152, 10.1016/j.chemphys.2008.02.055
Li, 1998, Generation of destabilized green fluorescent protein as a transcription reporter, J. Biol. Chem., 273, 34970, 10.1074/jbc.273.52.34970
Tumbar, 2004, Defining the epithelial stem cell niche in skin, Science, 303, 359, 10.1126/science.1092436
Foudi, 2009, Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells, Nat. Biotechnol., 27, 84, 10.1038/nbt.1517
Sauer, 1998, Inducible gene targeting in mice using the Cre/lox system, Methods, 14, 381, 10.1006/meth.1998.0593
Subach, 2009, Monomeric fluorescent timers that change color from blue to red report on cellular trafficking, Nat. Chem. Biol., 5, 118, 10.1038/nchembio.138
Gossen, 1992, Tight control of gene expression in mammalian cells by tetracycline-responsive promoters, Proc. Natl. Acad. Sci. U.S.A., 89, 5547, 10.1073/pnas.89.12.5547
Gossen, 1995, Efficacy of tetracycline-controlled gene expression is influenced by cell type: commentary, Biotechniques, 19, 213
Ando, 2002, An optical marker based on the UV-induced green-to-red photoconversion of a fluorescent protein, Proc. Natl. Acad. Sci. U.S.A., 99, 12651, 10.1073/pnas.202320599
Tomura, 2008, Monitoring cellular movement in vivo with photoconvertible fluorescence protein “Kaede” transgenic mice, Proc. Natl. Acad. Sci. U.S.A., 105, 10871, 10.1073/pnas.0802278105
Friedman, 2010, Real-time analysis of T cell receptors in naive cells in vitro and in vivo reveals flexibility in synapse and signaling dynamics, J. Exp. Med., 207, 2733, 10.1084/jem.20091201
Vig, 2009, Calcium signaling in immune cells, Nat. Immunol., 10, 21, 10.1038/ni.f.220
Mues, 2013, Real-time in vivo analysis of T cell activation in the central nervous system using a genetically encoded calcium indicator, Nat. Med., 19, 778, 10.1038/nm.3180
Macian, 2005, NFAT proteins: key regulators of T-cell development and function, Nat. Rev. Immunol., 5, 472, 10.1038/nri1632
Lodygin, 2013, A combination of fluorescent NFAT and H2B sensors uncovers dynamics of T cell activation in real time during CNS autoimmunity, Nat. Med., 19, 784, 10.1038/nm.3182
Marangoni, 2013, The transcription factor NFAT exhibits signal memory during serial T cell interactions with antigen-presenting cells, Immunity, 38, 237, 10.1016/j.immuni.2012.09.012
Hooijberg, 2000, NFAT-controlled expression of GFP permits visualization and isolation of antigen-stimulated primary human T cells, Blood, 96, 459, 10.1182/blood.V96.2.459
Ponomarev, 2001, Imaging TCR-dependent NFAT-mediated T-cell activation with positron emission tomography in vivo, Neoplasia, 3, 480, 10.1038/sj.neo.7900204
Moran, 2011, T cell receptor signal strength in Treg and iNKT cell development demonstrated by a novel fluorescent reporter mouse, J. Exp. Med., 208, 1279, 10.1084/jem.20110308
Mahmud, 2014, Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells, Nat. Immunol., 15, 473, 10.1038/ni.2849
Fulton, 2015, The TCR's sensitivity to self peptide-MHC dictates the ability of naive CD8(+) T cells to respond to foreign antigens, Nat. Immunol., 16, 107, 10.1038/ni.3043
Zhu, 2012, The transcription factor T-bet is induced by multiple pathways and prevents an endogenous Th2 cell program during Th1 cell responses, Immunity, 37, 660, 10.1016/j.immuni.2012.09.007
Grote, 2006, Pax 2/8-regulated Gata 3 expression is necessary for morphogenesis and guidance of the nephric duct in the developing kidney, Development, 133, 53, 10.1242/dev.02184
Eberl, 2004, An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells, Nat. Immunol., 5, 64, 10.1038/ni1022
Gimferrer, 2011, Regulation of GATA-3 expression during CD4 lineage differentiation, J. Immunol., 186, 3892, 10.4049/jimmunol.1003505
Ivanov, 2006, The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells, Cell, 126, 1121, 10.1016/j.cell.2006.07.035
Nowak, 2009, IL-9 as a mediator of Th17-driven inflammatory disease, J. Exp. Med., 206, 1653, 10.1084/jem.20090246
Sharma, 2009, Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes, Blood, 113, 6102, 10.1182/blood-2008-12-195354
Shaw, 2012, Microbiota-induced IL-1beta, but not IL-6, is critical for the development of steady-state TH17 cells in the intestine, J. Exp. Med., 209, 251, 10.1084/jem.20111703
Chalmin, 2012, Stat3 and Gfi-1 transcription factors control Th17 cell immunosuppressive activity via the regulation of ectonucleotidase expression, Immunity, 36, 362, 10.1016/j.immuni.2011.12.019
Kuczma, 2009, Foxp3-deficient regulatory T cells do not revert into conventional effector CD4+ T cells but constitute a unique cell subset, J. Immunol., 183, 3731, 10.4049/jimmunol.0800601
Fontenot, 2005, Regulatory T cell lineage specification by the forkhead transcription factor foxp3, Immunity, 22, 329, 10.1016/j.immuni.2005.01.016
Wan, 2005, Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter, Proc. Natl. Acad. Sci. U.S.A., 102, 5126, 10.1073/pnas.0501701102
Bettelli, 2006, Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells, Nature, 441, 235, 10.1038/nature04753
Haribhai, 2007, Regulatory T cells dynamically control the primary immune response to foreign antigen, J. Immunol., 178, 2961, 10.4049/jimmunol.178.5.2961
Wang, 2008, Th2 lymphoproliferative disorder of LatY136F mutant mice unfolds independently of TCR-MHC engagement and is insensitive to the action of Foxp3+ regulatory T cells, J. Immunol., 180, 1565, 10.4049/jimmunol.180.3.1565
Rubtsov, 2008, Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces, Immunity, 28, 546, 10.1016/j.immuni.2008.02.017
Rubtsov, 2010, Stability of the regulatory T cell lineage in vivo, Science, 329, 1667, 10.1126/science.1191996
Zhou, 2008, Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity, J. Exp. Med., 205, 1983, 10.1084/jem.20080707
Kim, 2007, Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice, Nat. Immunol., 8, 191, 10.1038/ni1428
Lahl, 2007, Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease, J. Exp. Med., 204, 57, 10.1084/jem.20061852
Feuerer, 2009, How punctual ablation of regulatory T cells unleashes an autoimmune lesion within the pancreatic islets, Immunity, 31, 654, 10.1016/j.immuni.2009.08.023
Jung, 2002, In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens, Immunity, 17, 211, 10.1016/S1074-7613(02)00365-5
Saito, 2001, Diphtheria toxin receptor-mediated conditional and targeted cell ablation in transgenic mice, Nat. Biotechnol., 19, 746, 10.1038/90795
Jeremiah, 2011, Genetic tools for analysis of FoxP3+ regulatory T cells in vivo, Methods Mol. Biol., 707, 105, 10.1007/978-1-61737-979-6_8
Fohse, 2013, Differential postselection proliferation dynamics of alphabeta T cells, Foxp3+ regulatory T cells, and invariant NKT cells monitored by genetic pulse labeling, J. Immunol., 191, 2384, 10.4049/jimmunol.1301359
Sakaue-Sawano, 2008, Visualizing spatiotemporal dynamics of multicellular cell-cycle progression, Cell, 132, 487, 10.1016/j.cell.2007.12.033
Marchingo, 2014, T cell signaling. Antigen affinity, costimulation, and cytokine inputs sum linearly to amplify T cell expansion, Science, 346, 1123, 10.1126/science.1260044
Kinjyo, 2015, Real-time tracking of cell cycle progression during CD8+ effector and memory T-cell differentiation, Nat. Commun., 6, 6301, 10.1038/ncomms7301
Bahl, 2010, Analysis of apoptosis of memory T cells and dendritic cells during the early stages of viral infection or exposure to toll-like receptor agonists, J. Virol., 84, 4866, 10.1128/JVI.02571-09
Garrod, 2012, Dissecting T cell contraction in vivo using a genetically encoded reporter of apoptosis, Cell Rep., 2, 1438, 10.1016/j.celrep.2012.10.015
Saparov, 1999, Interleukin-2 expression by a subpopulation of primary T cells is linked to enhanced memory/effector function, Immunity, 11, 271, 10.1016/S1074-7613(00)80102-8
Yui, 2001, A new regulatory region of the IL-2 locus that confers position-independent transgene expression, J. Immunol., 166, 1730, 10.4049/jimmunol.166.3.1730
Amado, 2013, IL-2 coordinates IL-2-producing and regulatory T cell interplay, J. Exp. Med., 210, 2707, 10.1084/jem.20122759
Kumar, 2005, A cytokine promoter/yellow fluorescent protein reporter transgene serves as an early activation marker of lymphocyte subsets, Cell. Immunol., 237, 131, 10.1016/j.cellimm.2005.11.003
Mohrs, 2005, A two-step process for cytokine production revealed by IL-4 dual-reporter mice, Immunity, 23, 419, 10.1016/j.immuni.2005.09.006
Repass, 2009, IL7-hCD25 and IL7-Cre BAC transgenic mouse lines: new tools for analysis of IL-7 expressing cells, Genesis, 47, 281, 10.1002/dvg.20497
Shalapour, 2010, Commensal microflora and interferon-gamma promote steady-state interleukin-7 production in vivo, Eur. J. Immunol., 40, 2391, 10.1002/eji.201040441
Gerlach, 2014, TH9 cells that express the transcription factor PU.1 drive T cell-mediated colitis via IL-9 receptor signaling in intestinal epithelial cells, Nat. Immunol., 15, 676, 10.1038/ni.2920
Bouabe, 2012, Cytokine reporter mice: the special case of IL-10, Scand. J. Immunol., 75, 553, 10.1111/j.1365-3083.2012.02695.x
Croxford, 2009, Cutting edge: an IL-17F-CreEYFP reporter mouse allows fate mapping of Th17 cells, J. Immunol., 182, 1237, 10.4049/jimmunol.182.3.1237
Lee, 2009, Late developmental plasticity in the T helper 17 lineage, Immunity, 30, 92, 10.1016/j.immuni.2008.11.005
Ahlfors, 2014, IL-22 fate reporter reveals origin and control of IL-22 production in homeostasis and infection, J. Immunol., 193, 4602, 10.4049/jimmunol.1401244
Scheu, 2008, Visualization of IFNbeta production by plasmacytoid versus conventional dendritic cells under specific stimulation conditions in vivo, Proc. Natl. Acad. Sci. U.S.A., 105, 20416, 10.1073/pnas.0808537105
Stetson, 2003, Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function, J. Exp. Med., 198, 1069, 10.1084/jem.20030630
Reinhardt, 2009, Cytokine-secreting follicular T cells shape the antibody repertoire, Nat. Immunol., 10, 385, 10.1038/ni.1715
Li, 2007, T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation, Immunity, 26, 579, 10.1016/j.immuni.2007.03.014
Matsuda, 2003, Mouse V alpha 14i natural killer T cells are resistant to cytokine polarization in vivo, Proc. Natl. Acad. Sci. U.S.A., 100, 8395, 10.1073/pnas.1332805100
Reinhardt, 2015, A novel model for IFN-gamma-mediated autoinflammatory syndromes, J. Immunol., 194, 2358, 10.4049/jimmunol.1401992
Beuneu, 2010, Visualizing the functional diversification of CD8+ T cell responses in lymph nodes, Immunity, 33, 412, 10.1016/j.immuni.2010.08.016
Jacob, 1999, Modelling T-cell memory by genetic marking of memory T cells in vivo, Nature, 399, 593, 10.1038/21208
Bannard, 2009, Secondary replicative function of CD8+ T cells that had developed an effector phenotype, Science, 323, 505, 10.1126/science.1166831
Chudakov, 2010, Fluorescent proteins and their applications in imaging living cells and tissues, Physiol. Rev., 90, 1103, 10.1152/physrev.00038.2009
Mouchacca, 2013, Visualization of cytolytic T cell differentiation and granule exocytosis with T cells from mice expressing active fluorescent granzyme B, PLoS ONE, 8, e67239, 10.1371/journal.pone.0067239
Bird, 2010, Use of granzyme B-based fluorescent protein reporters to monitor granzyme distribution and granule integrity in live cells, Biol. Chem., 391, 999, 10.1515/bc.2010.099
Martina, 2011, Imaging of lytic granule exocytosis in CD8+ cytotoxic T lymphocytes reveals a modified form of full fusion, Cell. Immunol., 271, 267, 10.1016/j.cellimm.2011.07.004
Liu, 2011, Two modes of lytic granule fusion during degranulation by natural killer cells, Immunol. Cell Biol., 89, 728, 10.1038/icb.2010.167
van Heijst, 2009, Recruitment of antigen-specific CD8+ T cells in response to infection is markedly efficient, Science, 325, 1265, 10.1126/science.1175455
Gerlach, 2013, Heterogeneous differentiation patterns of individual CD8+ T cells, Science, 340, 635, 10.1126/science.1235487
Buchholz, 2013, Disparate individual fates compose robust CD8+ T cell immunity, Science, 340, 630, 10.1126/science.1235454
Livet, 2007, Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system, Nature, 450, 56, 10.1038/nature06293
Snippert, 2010, Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells, Cell, 143, 134, 10.1016/j.cell.2010.09.016
Ghigo, 2013, Multicolor fate mapping of Langerhans cell homeostasis, J. Exp. Med., 210, 1657, 10.1084/jem.20130403
Jarjour, 2014, Fate mapping reveals origin and dynamics of lymph node follicular dendritic cells, J. Exp. Med., 211, 1109, 10.1084/jem.20132409
Weber, 2011, RGB marking facilitates multicolor clonal cell tracking, Nat. Med., 17, 504, 10.1038/nm.2338
Weber, 2012, RGB marking with lentiviral vectors for multicolor clonal cell tracking, Nat. Protoc., 7, 839, 10.1038/nprot.2012.026
Harrington, 2008, Memory CD4 T cells emerge from effector T-cell progenitors, Nature, 452, 356, 10.1038/nature06672
Dunkle, 2013, Transfer of CD8+ T cell memory using Bcl-2 as a marker, J. Immunol., 190, 940, 10.4049/jimmunol.1103481
Stewart-Ornstein, 2013, Msn2 coordinates a stoichiometric gene expression program, Curr. Biol., 23, 2336, 10.1016/j.cub.2013.09.043
Siuti, 2013, Synthetic circuits integrating logic and memory in living cells, Nat. Biotechnol., 31, 448, 10.1038/nbt.2510
Haruyama, 2009, Overview: engineering transgenic constructs and mice, Curr. Protoc. Cell Biol., 19, 10.1002/0471143030.cb1910s42
Croxford, 2011, Cytokine reporter mice in immunological research: perspectives and lessons learned, Immunology, 132, 1, 10.1111/j.1365-2567.2010.03372.x
Zambrowicz, 1997, Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells, Proc. Natl. Acad. Sci. U.S.A., 94, 3789, 10.1073/pnas.94.8.3789
Mizuguchi, 2000, IRES-dependent second gene expression is significantly lower than cap-dependent first gene expression in a bicistronic vector, Mol. Ther., 1, 376, 10.1006/mthe.2000.0050
Trichas, 2008, Use of the viral 2A peptide for bicistronic expression in transgenic mice, BMC Biol., 6, 40, 10.1186/1741-7007-6-40
Buus, 1987, The relation between major histocompatibility complex (MHC) restriction and the capacity of Ia to bind immunogenic peptides, Science, 235, 1353, 10.1126/science.2435001
Rosenzweig, 2001, Induction of cytotoxic T lymphocyte and antibody responses to enhanced green fluorescent protein following transplantation of transduced CD34(+) hematopoietic cells, Blood, 97, 1951, 10.1182/blood.V97.7.1951
Stripecke, 1999, Immune response to green fluorescent protein: implications for gene therapy, Gene Ther., 6, 1305, 10.1038/sj.gt.3300951
Davey, 2013, Identification of a MHC I-restricted epitope of DsRed in C57BL/6 mice, Mol. Immunol., 53, 450, 10.1016/j.molimm.2012.10.003
Mantovani, 2000, Investigating T-cell memory, Nature, 407, 40, 10.1038/35024159
Cheng, 2013, Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system, Cell Res., 23, 1163, 10.1038/cr.2013.122
Mali, 2013, CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering, Nat. Biotechnol., 31, 833, 10.1038/nbt.2675