Kháng Aspirin: Kỹ Thuật Đánh Giá Lâm Sàng và Di truyền Học Phân Tử

Human Physiology - Tập 43 - Trang 904-909 - 2018
M. M. Tanashyan1, M. A. Domashenko1, A. A. Raskurazhev1
1Research Center of Neurology, Moscow, Russia

Tóm tắt

Bài báo thảo luận về các vấn đề liên quan đến việc cá nhân hóa các biện pháp phòng ngừa đột quỵ thiếu máu cục bộ, đặc biệt là những vấn đề liên quan đến kháng thuốc của một trong những loại thuốc chống tiểu cầu phổ biến nhất, aspirin. Bài viết cung cấp một ghi chú lịch sử ngắn gọn về việc nghiên cứu axit acetylsalicylic. Bài báo đề cập đến các yếu tố nguyên nhân và dịch tễ học của kháng aspirin. Một phân tích và so sánh các kỹ thuật khác nhau để đánh giá hiện tượng này được thực hiện. Riêng biệt, một khía cạnh di truyền học phân tử của bệnh lý được xem xét. Cuối cùng, các khuyến nghị để vượt qua sự dung nạp đối với liệu pháp aspirin được cung cấp.

Từ khóa

#kháng aspirin #đột quỵ thiếu máu cục bộ #phòng ngừa #thuốc chống tiểu cầu #axit acetylsalicylic #dịch tễ học #đánh giá lâm sàng #di truyền học phân tử

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