Asian‐Pacific consensus statement on the management of chronic hepatitis B: a 2005 update

Liver International - Tập 25 Số 3 - Trang 472-489 - 2005
Yun‐Fan Liaw1, Nancy Leung2, R Guan3, George Lau4, I Merican5, Geoffrey W. McCaughan6, Edward Gane7, Jia‐Horng Kao8, Masao Omata9
1Liver Research Unit, Chang Gung Memorial Hospital, Taipei, Taiwan
2Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, Chinese University of Hong Kong, Hong Kong, China,
3Medical Clinic One, Mount Elizabeth Medical Centre, Singapore,
4Faculty of Medicine, University of Hong Kong Hong Kong China
5Hospital Selayang, Institute for Medical Research, Kuala Lumpur, Malaysia,
6AW Morrow Gastroenterology and Liver Laboratory, Royal Prince Alfred Hospital, Sydney, Australia,
7New Zealand Liver Transplant Unit, Auckland Hospital, Auckland, New Zealand
8Hepatitis Research Centre, National Taiwan University Hospital, Taipei, Taiwan
9Department of Gastroenterology, University of Tokyo, Tokyo, Japan

Tóm tắt

Abstract:
Background/Aims: A large amount of new data on the treatment of chronic hepatitis B has become available such that the 2003 consensus statement requires revision and update.Methods: New data were presented, discussed and debated in an expert pre‐meeting to draft a revision. The revised contents were finalized after discussion in a general meeting of APASL.Results: Conceptual background, including the efficacy and safety profile of currently available and emerging drugs, was reviewed. Nineteen recommendations were formed and unresolved issues and areas for further study were suggested.Conclusion: The current therapy of chronic hepatitis B is modestly effective but not satisfactory. The development of new drugs and new strategies is required to further improve the outcomes of treatment.

Từ khóa


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