Arctigenic acid, the key substance responsible for the hypoglycemic activity of Fructus Arctii

Phytomedicine - Tập 22 - Trang 128-137 - 2015
Zhaohui Xu1, Chenchen Gu1, Kai Wang2, Jiaxing Ju1, Haiying Wang3, Kefeng Ruan1, Yi Feng1
1Engineering Research Center of Modern Preparation Technology of Traditional Chinese Medicine, Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
2Center for Drug Safety Evaluation, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
3School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China

Tài liệu tham khảo

Akash, 2013, Goto-Kakizaki rats: its suitability as non-obese diabetic animal model for spontaneous type 2 diabetes mellitus, Curr. Diab. Rev., 9, 1, 10.2174/15733998113099990069 2011, Diagnosis and classification of diabetes mellitus, Diabetes Care, 34, S62, 10.2337/dc11-S062 Atsuko, 2006, Insulin and nateglinide reduce monocyte adhesion to endothelial cells in Goto-Kakizaki rats exhibiting repetitive blood glucose fluctuation, Biochem. Biophys. Res. Commun., 350, 195, 10.1016/j.bbrc.2006.09.039 Callahan, 2000, Type 2 diabetes mellitus in adolescents, Curr. Opin. Pediatr., 12, 310, 10.1097/00008480-200008000-00004 Ceriello, 2008, Guideline for management of postmeal glucose, Nutr. Metab. Cardiovasc. Dis., 18, S17, 10.1016/j.numecd.2008.01.012 Ceriello, 2006, Postprandial hyperglycemia and cardiovascular complications of diabetes: an update, Nutr. Metab. Cardiovasc. Dis., 16, 453, 10.1016/j.numecd.2006.05.006 Chen, 1999, Fructus Arctii is hypoglycemic and good for back and joints, Fujian J. TCM, 30, 17 David, 2001, Importance of postprandial glucose control, South Med. J., 94, 804, 10.1097/00007611-200108000-00010 Gao, 2013, Hydrolysis is the dominating in vivo metabolism pathway for arctigenin: identification of novel metabolites of arctigenin by LC/MS/MS after oral administration in rats, Planta Med., 79, 471, 10.1055/s-0032-1328332 George, 2011, Quo vadis nateglinide? Ten-year perspective, Drug Eval., 12, 2097 Hisashi, 1988, N-acylphenylalanines and related compounds: a new class of oral hypoglycemic agents, J. Med. Chem., 31, 2092, 10.1021/jm00119a007 Ivorra, 1989, A review of natural products and plants as potential antidiabetic drugs, J. Ethnopharmacol., 27, 243, 10.1016/0378-8741(89)90001-9 Keilson, 2000, Synergistic effects of nateglinide and meal administration on insulin secretion in patients with type 2 diabetes mellitus, J. Clin. Endocrinol. Metab., 85, 1081, 10.1210/jcem.85.3.6446 Keiko, 2005, Isolation and identification of potent stimulatory allelopathic substances exuded from germinating Burdoch (Arctium Lappa) seeds, Heterocycles, 65, 1431, 10.3987/COM-05-10361 Liu, 2011, The protection effect of arctiin on filtration barrier injury of kidney glomerulus in diabetic nephropathy rats, West China J. Pharm. Sci., 26, 536 Luna, 1990 Mohammadi, 2008, Evaluation of hypoglycemic effect of Morus alba in animal model, Indian J. Pharmacol., 40, 15, 10.4103/0253-7613.40483 Twaij, 1983, Some pharmacological, toxicological and phytochemical investigations on Centaurea phyllocephala, J. Ethnopharmacol., 9, 299, 10.1016/0378-8741(83)90037-5 Wang, 2004, Clinical observation on treatment of diabetic nephropathy with compound Fructus Arctii mixture, Chin. J. Integr. Med., 24, 589 Xu, 2006, Chemical constituents of antihyperglycemic active fraction from Arctium lappa., Chin. J. Nat. Med., 4, 444 Xu, 2008, The antidiabetic activity of total lignan from Fructus Arctii against alloxan-induced diabetes in mice and rats., Phytother. Res., 22, 97, 10.1002/ptr.2273 Yan, 1993, Effects of extract from Fructus Arctii on blood glucose and immune function in mice, Northwest Pharm. J., 8, 75 Yoshiro, 2002, Decreased blood glucose excursion by nateglinide ameliorated neuropathic changes in Goto-Kakizaki rats, an animal model of non-obese type 2 diabetes, Metabolism, 51, 1452, 10.1053/meta.2002.35195 Zhai, 2009, Study on quality standard of Tangshenkang Soft Capsules, Chin. Tradit. Patent Med., 31, 1708 Zhang, 2007, Study on effect of Arctium Lappa on experimental diabetic mice, Lishizhen Med. Mater. Medica Res., 18, 2222