Applying a Multicriteria Decision Analysis (MCDA) Approach to Elicit Stakeholders’ Preferences in Italy: The Case of Obinutuzumab for Rituximab-Refractory Indolent Non-Hodgkin Lymphoma (iNHL)

Martina Garau1, Grace Hampson1, Nancy Devlin1, Nicola Amedeo Mazzanti2, A. Profico2
1Office of Health Economics, London, UK
2Roche S.P.A, Milan, Italy

Tóm tắt

Từ khóa


Tài liệu tham khảo

HTAi Patient and Citizen Involvement. Good Practice Examples of Patient and Public Involvement in Health Technology Assessment. 2015. http://www.htai.org/fileadmin/HTAi_Files/ISG/PatientInvolvement/EffectiveInvolvement/Good_Practice_Examples_Feb_2015.pdf . Accessed 14 Aug 2017.

SMC. PACE—patient and clinician engagement. Factsheet. 2015. https://www.scottishmedicines.org.uk/files/PACE/PACE_factsheet_0417.pdf . Accessed 14 Aug 2017.

Shah KK, Mestre-Ferrandiz J, Towse A, Smyth EN. A review of health technology appraisals: case studies in oncology. Int J Technol Assess Health Care. 2013;29(1):101–9.

Devlin N, Sussex J. Incorporating multiple criteria in HTA: methods and processes. OHE Monograph. London: Office of Health Economics; 2011.

Danner M, Hummel JM, Volz F, van Manen JG, Wiegard B, Dintsios CM, et al. Integrating patients’ views into health technology assessment: analytic hierarchy process (AHP) as a method to elicit patient preferences. Int J Technol Assess Health Care. 2011;27(4):369–75.

Thokala P, Devlin N, Marsh K, Baltussen R, Boysen M, Kalo Z, et al. Multiple criteria decision analysis for health care decision making-an introduction: report 1 of the ISPOR MCDA emerging good practices task force. Value Health. 2016;19(1):1–13.

Radaelli G, Lettieri E, Masella C, Merlino L, Strada A, Tringali M. Implementation of EUnetHTA core Model(R) in Lombardia: the VTS framework. Int J Technol Assess Health Care. 2014;30(1):105–12.

Castro H, Tringali M, Cleemput I, Devriese S, Leoni O, Lettieri E. Advancing MCDA and HTA into coverage decision-making. In: Marsh K, Goetghebeur M, Thokala P, Baltussen R, editors. Multi-criteria decision analysis to support healthcare decisions. Cham: Springer International Publishing; 2017. p. 119–46.

Wahlster P, Goetghebeur M, Schaller S, Kriza C, Kolominsky-Rabas P. Exploring the perspectives and preferences for HTA across German healthcare stakeholders using a multi-criteria assessment of a pulmonary heart sensor as a case study. Health Res Policy Syst. 2015;13:24.

Bentley TG, Cohen JT, Elkin EB, Huynh J, Mukherjea A, Neville TH, et al. Validity and reliability of value assessment frameworks for new cancer drugs. Value Health. 2017;20(2):200–5.

Wagner M, Khoury H, Willet J, Rindress D, Goetghebeur M. Can the EVIDEM framework tackle issues raised by evaluating treatments for rare diseases: analysis of issues and policies, and context-specific adaptation. Pharmacoeconomics. 2016;34(3):285–301.

Daniels N, Sabin JE. Accountability for reasonableness: an update. BMJ. 2008;337:a1850.

Tony M, Wagner M, Khoury H, Rindress D, Papastavros T, Oh P, et al. Bridging health technology assessment (HTA) with multicriteria decision analyses (MCDA): field testing of the EVIDEM framework for coverage decisions by a public payer in Canada. BMC Health Serv Res. 2011;11:329.

Gilabert-Perramon A, Catalan A, Prat A, Fontanet M, Puig-Peiró R, Merino-Montero S, et al. Development of a multi-criteria decision analysis (MCDA) framework for health care decision-making in Catalonia (Spain): pilot study focused in orphan drugs. Vienna: ISPOR 19th Annual European Congress; 2016.

van Til J, Groothuis-Oudshoorn C, Lieferink M, Dolan J, Goetghebeur M. Does technique matter: a pilot study exploring weighting techniques for a multi-criteria decision support framework. Cost Eff Resour Alloc. 2014;12:22.

Sehn LH, Chua N, Mayer J, Dueck G, Trneny M, Bouabdallah K, et al. Obinutuzumab plus bendamustine versus bendamustine monotherapy in patients with rituximab-refractory indolent non-Hodgkin lymphoma (GADOLIN): a randomised, controlled, open-label, multicentre, phase 3 trial. Lancet Oncol. 2016;17(8):1081–93.

European Medicines Agency. Assessment report Gazyvaro Procedure No. EMEA/H/C/002799/II/0007. 2016. http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Assessment_Report_-_Variation/human/002799/WC500211313.pdf . Accessed 14 Aug 2017.

Lee L, Wang L, Crump M. Identification of potential surrogate end points in randomized clinical trials of aggressive and indolent non-Hodgkin’s lymphoma: correlation of complete response, time-to-event and overall survival end points. Ann Oncol. 2011;22(6):1392–403.

Belton V, Pictet J. A framework for group decision using a MCDA model: sharing, aggregating or comparing individual information? J Decis Syst. 1997;6(3):283–303.

Claxton K. Three questions to ask when examining MCDA. Value Outcomes Spotlight. 2015;1:10–8.

Marsh K, IJmerzan M, Thokala P, Baltussen R, Boysen M, Kalo Z, et al. Multiple criteria decision analysis for health care decision making—emerging good practices: report 2 of the ISPOR MCDA emerging good practices task force. Value Health. 2016;19(2):125–37.

Garau M, Devlin NJ. Using MCDA as a decision aid in health technology appraisal for coverage decisions: opportunities, challenges and unresolved questions. In: Marsh K, Goetghebeur M, Thokala P, Baltussen R, editors. Multi-criteria decision analysis to support healthcare decisions. Cham: Springer International Publishing; 2017. p. 277–98.

Golan O, Hansen P. Which health technologies should be funded? A prioritization framework based explicitly on value for money. Isr J Health Policy Res. 2012;1(1):44.

Sussex J, Towse A, Devlin N. Operationalizing value-based pricing of medicines: a taxonomy of approaches. Pharmacoeconomics. 2013;31(1):1–10.

Culyer A, McCabe C, Briggs A, Claxton K, Buxton M, Akehurst R, et al. Searching for a threshold, not setting one: the role of the National Institute for Health and Clinical Excellence. J Health Serv Res Policy. 2007;12(1):56–8.

Karlsberg Schaffer S, Sussex J, Devlin N, Walker A. Local health care expenditure plans and their opportunity costs. Health Policy. 2015;119(9):1237–44.

Appleby J, Devlin N, Parkin D, Buxton M, Chalkidou K. Searching for cost effectiveness thresholds in the NHS. Health Policy. 2009;91(3):239–45.

Claxton K, Martin S, Soares M, Rice N, Spackman E, Hinde S, et al. Methods for the estimation of the National Institute for Health and Care Excellence cost-effectiveness threshold. Health Technol Assess. 2015;19(14):1–503 (v–vi).

Baltussen R. Question is not whether but how to use MCDA. Value Outcomes Spotlight. 2015;1(1):14–6.

Marsh K, Caro JJ, Hamed A, Zaiser E. Amplifying each patient’s voice: a systematic review of multi-criteria decision analyses involving patients. Appl Health Econ Health Policy. 2017;15(2):155–62.

Mühlbacher AC, Kaczynski A. Making good decisions in healthcare with multi-criteria decision analysis: the use, current research and future development of MCDA. Appl Health Econ Health Policy. 2016;14(1):29–40.

Phillips LD. Best Practice for MCDA in Healthcare. In: Marsh K, Goetghebeur M, Thokala P, Baltussen R, editors. Multi-criteria decision analysis to support healthcare decisions. Cham: Springer International Publishing; 2017. p. 311–29.

Golan O, Hansen P, Kaplan G, Tal O. Health technology prioritization: which criteria for prioritizing new technologies and what are their relative weights? Health Policy. 2011;102(2–3):126–35.