Appetitive, antinociceptive, and hypothermic effects of vaped and injected Δ-9-tetrahydrocannabinol (THC) in rats: exposure and dose-effect comparisons by strain and sex

Pharmacology Biochemistry and Behavior - Tập 202 - Trang 173116 - 2021
Catherine F. Moore1, Catherine M. Davis1, Eric L. Harvey2, Michael A. Taffe2, Elise M. Weerts1
1Division of Behavioral Biology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
2Department of Psychiatry, University of California, San Diego, La Jolla, CA USA

Tài liệu tham khảo

Baassiri, 2017, Clouds and “throat hit”: effects of liquid composition on nicotine emissions and physical characteristics of electronic cigarette aerosols, Aerosol Sci. Technol., 51, 1231, 10.1080/02786826.2017.1341040 Badowski, 2016, Clinical utility of dronabinol in the treatment of weight loss associated with HIV and AIDS, HIV AIDS (Auckl), 8, 37 Berry, 2002, Tetrahydrocannabinol and endocannabinoids in feeding and appetite, Pharmacol. Ther., 95, 185, 10.1016/S0163-7258(02)00257-7 Britch, 2017, Cannabidiol-Delta(9)-tetrahydrocannabinol interactions on acute pain and locomotor activity, Drug Alcohol Depend., 175, 187, 10.1016/j.drugalcdep.2017.01.046 Brutman, 2019, Vapor cannabis exposure promotes genetic plasticity in the rat hypothalamus, Sci. Rep., 9, 16866, 10.1038/s41598-019-53516-4 Burston, 2010, Regional enhancement of cannabinoid CB₁ receptor desensitization in female adolescent rats following repeated Delta-tetrahydrocannabinol exposure, Br. J. Pharmacol, 161, 103, 10.1111/j.1476-5381.2010.00870.x Compton, 1993, Cannabinoid structure-activity relationships: correlation of receptor binding and in vivo activities, J. Pharmacol. Exp. Ther., 265, 218 Craft, 2019, Age-related differences in Delta(9)-tetrahydrocannabinol-induced antinociception in female and male rats, Exp. Clin. Psychopharmacol., 27, 338, 10.1037/pha0000257 D’Souza, 2016, Rapid changes in CB1 receptor availability in cannabis dependent males after abstinence from cannabis, Biol Psychiatry Cogn Neurosci Neuroimaging, 1, 60 Freels, 2020, Vaporized cannabis extracts have reinforcing properties and support conditioned drug-seeking behavior in rats, J. Neurosci., 40, 1897, 10.1523/JNEUROSCI.2416-19.2020 Giroud, 2015, E-cigarettes: a review of new trends in cannabis use, Int. J. Environ. Res. Public Health, 12, 9988, 10.3390/ijerph120809988 Goodman, S., Wadsworth, E., Leos-Toro, C., Hammond, D., International Cannabis Policy Study, t., 2020. Prevalence and forms of cannabis use in legal vs. illegal recreational cannabis markets. Int J Drug Policy 76, 102658. Higgs, 2005, Differential effects of two cannabinoid receptor agonists on progressive ratio responding for food and free-feeding in rats, Behav. Pharmacol., 16, 389, 10.1097/00008877-200509000-00011 Hirvonen, 2012, Reversible and regionally selective downregulation of brain cannabinoid CB1 receptors in chronic daily cannabis smokers, Mol. Psychiatry, 17, 642, 10.1038/mp.2011.82 Irimia, 2015, Persistent effects of chronic Delta9-THC exposure on motor impulsivity in rats, Psychopharmacology, 232, 3033, 10.1007/s00213-015-3942-x Jager, 2014, The endocannabinoid system and appetite: relevance for food reward, Nutr. Res. Rev., 27, 172, 10.1017/S0954422414000080 Javadi-Paydar, 2018, Effects of Delta9-THC and cannabidiol vapor inhalation in male and female rats, Psychopharmacology, 235, 2541, 10.1007/s00213-018-4946-0 Koch, 2001, Delta(9)-THC stimulates food intake in Lewis rats: effects on chow, high-fat and sweet high-fat diets, Pharmacol. Biochem. Behav., 68, 539, 10.1016/S0091-3057(01)00467-1 Lacroix, 2012, Fast liquid chromatography/tandem mass spectrometry determination of cannabinoids in micro volume blood samples after dabsyl derivatization, J Chromatogr B Analyt Technol Biomed Life Sci, 905, 85, 10.1016/j.jchromb.2012.08.006 Lee, 2016, Online survey characterizing vaporizer use among cannabis users, Drug Alcohol Depend., 159, 227, 10.1016/j.drugalcdep.2015.12.020 Lichtman, 2000, Pharmacological evaluation of aerosolized cannabinoids in mice, Eur. J. Pharmacol., 399, 141, 10.1016/S0014-2999(00)00321-6 Manwell, 2014, A vapourized Delta(9)-tetrahydrocannabinol (Delta(9)-THC) delivery system part I: development and validation of a pulmonary cannabinoid route of exposure for experimental pharmacology studies in rodents, J. Pharmacol. Toxicol. Methods, 70, 120, 10.1016/j.vascn.2014.06.006 Manwell, 2014, A vapourized Delta(9)-tetrahydrocannabinol (Delta(9)-THC) delivery system part II: comparison of behavioural effects of pulmonary versus parenteral cannabinoid exposure in rodents, J. Pharmacol. Toxicol. Methods, 70, 112, 10.1016/j.vascn.2014.06.004 Metna-Laurent, M., Mondesir, M., Grel, A., Vallee, M., Piazza, P.V., 2017. Cannabinoid-Induced Tetrad in Mice. Curr Protoc Neurosci 80, 9 59 51-59 59 10. Miliano, 2020, Modeling drug exposure in rodents using e-cigarettes and other electronic nicotine delivery systems, J. Neurosci. Methods, 330, 108458, 10.1016/j.jneumeth.2019.108458 Moore, 2020, Translational models of cannabinoid vapor exposure in laboratory animals, Behav. Pharmacol. Nguyen, 2016, Inhaled delivery of Delta(9)-tetrahydrocannabinol (THC) to rats by e-cigarette vapor technology, Neuropharmacology, 109, 112, 10.1016/j.neuropharm.2016.05.021 Nguyen, 2018, Tolerance to hypothermic and antinoceptive effects of 9-tetrahydrocannabinol (THC) vapor inhalation in rats, Pharmacol. Biochem. Behav., 172, 33, 10.1016/j.pbb.2018.07.007 Nguyen, 2019, Delta(9)-tetrahydrocannabinol attenuates oxycodone self-administration under extended access conditions, Neuropharmacology, 151, 127, 10.1016/j.neuropharm.2019.04.010 Nguyen, 2020, Explication of CB1 receptor contributions to the hypothermic effects of Delta(9)-tetrahydrocannabinol (THC) when delivered by vapor inhalation or parenteral injection in rats, Drug Alcohol Depend., 214, 108166, 10.1016/j.drugalcdep.2020.108166 Nguyen, 2020, Lasting effects of repeated (9) -tetrahydrocannabinol vapour inhalation during adolescence in male and female rats, Br. J. Pharmacol., 177, 188, 10.1111/bph.14856 Olarte-Sanchez, 2015, Quantitative analysis of performance on a progressive-ratio schedule: effects of reinforcer type, food deprivation and acute treatment with Delta(9)-tetrahydrocannabinol (THC), Behav. Process., 113, 122, 10.1016/j.beproc.2015.01.014 Richardson, 1996, Progressive ratio schedules in drug self-administration studies in rats: a method to evaluate reinforcing efficacy, J. Neurosci. Methods, 66, 1, 10.1016/0165-0270(95)00153-0 Schauer, 2020, Modes of marijuana use - smoking, vaping, eating, and dabbing: results from the 2016 BRFSS in 12 states, Drug Alcohol Depend., 209, 107900, 10.1016/j.drugalcdep.2020.107900 Solinas, 2005, Motivational effects of cannabinoids and opioids on food reinforcement depend on simultaneous activation of cannabinoid and opioid systems, Neuropsychopharmacology, 30, 2035, 10.1038/sj.npp.1300720 Spindle, 2018, Acute effects of smoked and vaporized cannabis in healthy adults who infrequently use cannabis: a crossover trial, JAMA Netw. Open, 1, 10.1001/jamanetworkopen.2018.4841 Spindle, 2018, Effects of electronic cigarette liquid solvents propylene glycol and vegetable glycerin on user nicotine delivery, heart rate, subjective effects, and puff topography, Drug Alcohol Depend., 188, 193, 10.1016/j.drugalcdep.2018.03.042 Spindle, 2020, Pharmacodynamic effects of vaporized and oral cannabidiol (CBD) and vaporized CBD-dominant cannabis in infrequent cannabis users, Drug Alcohol Depend., 211, 107937, 10.1016/j.drugalcdep.2020.107937 Taffe, 2015, Cannabidiol fails to reverse hypothermia or locomotor suppression induced by Delta(9) -tetrahydrocannabinol in Sprague-Dawley rats, Br. J. Pharmacol., 172, 1783, 10.1111/bph.13024 Taffe, M.A., Creehan, K.M., Vandewater, S.A., Kerr, T.M., Cole, M., 2020. Effects of Delta(9)-tetrahydrocannabinol (THC) vapor inhalation in Sprague-Dawley and Wistar rats. Exp Clin Psychopharmacol, Published online April 17, 2020. doi: 2010.1037/pha0000373. Trivers, 2019, Substances used in electronic vapor products among adults in the United States, 2017, Addict. Behav. Rep., 10, 100222 Tseng, 2001, Sex differences in antinociceptive and motoric effects of cannabinoids, Eur. J. Pharmacol., 430, 41, 10.1016/S0014-2999(01)01267-5 Tseng, 2004, Pharmacokinetic factors in sex differences in Delta 9-tetrahydrocannabinol-induced behavioral effects in rats, Behav. Brain Res., 154, 77, 10.1016/j.bbr.2004.01.029 Wiley, 2007, Pharmacological effects of acute and repeated administration of Delta(9)-tetrahydrocannabinol in adolescent and adult rats, J. Pharmacol. Exp. Ther, 320, 1097, 10.1124/jpet.106.108126 Wilson, 2002, Physiochemical and pharmacological characterization of a Delta(9)-THC aerosol generated by a metered dose inhaler, Drug Alcohol Depend., 67, 259, 10.1016/S0376-8716(02)00078-9