Apicoplast fatty acid biosynthesis as a target for medical intervention in apicomplexan parasites
Tài liệu tham khảo
Azzouz, 2002, Evidence for de novo sphingolipid biosynthesis in Toxoplasma gondii, Int. J. Parasitol., 32, 677, 10.1016/S0020-7519(02)00009-7
Bahl, 2002, PlasmoDB: the Plasmodium genome resource. An integrated database providing tools for accessing, analyzing and mapping expression and sequence data (both finished and unfinished), Nucleic Acids Res., 30, 87, 10.1093/nar/30.1.87
Baldauf, 2000, A kingdom-level phylogeny of eukaryotes based on combined protein data, Science, 290, 972, 10.1126/science.290.5493.972
Campbell, 2001, Bacterial fatty acid biosynthesis: targets for antibacterial drug discovery, Annu. Rev. Microbiol., 55, 305, 10.1146/annurev.micro.55.1.305
Camps, 2002, An rRNA mutation identifies the apicoplast as the target for clindamycin in Toxoplasma gondii, Mol. Microbiol., 43, 1309, 10.1046/j.1365-2958.2002.02825.x
Carlton, 2002, Genome sequence and comparative analysis of the model rodent malaria parasite Plasmodium yoelii, Nature, 419, 512, 10.1038/nature01099
Carlton, 2002, Rodent models of malaria in the genomics era, Trends Parasitol., 18, 100, 10.1016/S1471-4922(01)02229-2
Carucci, 2001, Functional genomic technologies applied to the control of the human malaria parasite, Plasmodium falciparum, Pharmacogenomics, 2, 137, 10.1517/14622416.2.2.137
Cascante, 2002, Metabolic control analysis in drug discovery and disease, Nat. Biotechnol., 20, 243, 10.1038/nbt0302-243
Charron, 2002, Host cells: mobilizable lipid resources for the intracellular parasite Toxoplasma gondii, J. Cell Sci., 115, 3049, 10.1242/jcs.115.15.3049
Chirala, 2001, Human fatty acid synthase: role of interdomain in the formation of catalytically active synthase dimer, Proc. Natl Acad. Sci. USA, 98, 3104, 10.1073/pnas.051635998
Coombs, 2002, Recent advances in the search for new anti-coccidial drugs, Int. J. Parasitol., 32, 497, 10.1016/S0020-7519(01)00354-X
Cronan, 2002, Multi-subunit acetyl-CoA carboxylases, Prog. Lipid Res., 41, 407, 10.1016/S0163-7827(02)00007-3
DeRocher, 2000, Analysis of targeting sequences demonstrates that trafficking to the Toxoplasma gondii plastid branches off the secretory system, J. Cell Sci., 113, 3969, 10.1242/jcs.113.22.3969
Derouin, 2001, Anti-toxoplasmosis drugs, Curr. Opin. Investig. Drugs, 2, 1368
Devine, 1997, Mechanism of resistance to acetyl-coenzyme A carboxylase inhibitors: a review, Pestic. Sci., 51, 259, 10.1002/(SICI)1096-9063(199711)51:3<259::AID-PS644>3.0.CO;2-S
Devine, 2000, Altered target sites as mechanism of herbicide resistance, Crop Prot., 19, 881, 10.1016/S0261-2194(00)00123-X
Fichera, 1997, A plastid organelle as a drug target in apicomplexan parasites, Nature, 390, 407, 10.1038/37132
Foth, 2003, Dissecting apicoplast targeting in the malaria parasite Plasmodium falciparum, Science, 299, 705, 10.1126/science.1078599
Gardner, 2002, Genome sequence of the human malaria parasite Plasmodium falciparum, Nature, 419, 498, 10.1038/nature01097
Gerold, 2001, Biosynthesis of glycosphingolipids de-novo by the human malaria parasite Plasmodium falciparum, Mol. Biochem. Parasitol., 112, 29, 10.1016/S0166-6851(00)00336-4
Gleeson, 2000, The plastid in Apicomplexa: what use is it?, Int. J. Parasitol., 30, 1053, 10.1016/S0020-7519(00)00100-4
Greenwood, 2002, Malaria in 2002, Nature, 415, 670, 10.1038/415670a
Gueguen, 2000, Fatty acid and lipoic acid biosynthesis in higher plant mitochondria, J. Biol. Chem., 275, 5016, 10.1074/jbc.275.7.5016
Harwood, 1996, Recent advances in the biosynthesis of plant fatty acids, Biochim. Biophys. Acta, 1301, 7, 10.1016/0005-2760(95)00242-1
He, 2001, A plastid segregation defect in the protozoan parasite Toxoplasma gondii, EMBO J., 20, 330, 10.1093/emboj/20.3.330
Heath, 2001, Lipid biosynthesis as a target for antibacterial agents, Prog. Lipid Res., 40, 467, 10.1016/S0163-7827(01)00012-1
Heath, 2002, Inhibitors of fatty acid synthesis as antimicrobial chemotherapeutics, Appl. Microbiol. Biotechnol., 58, 695, 10.1007/s00253-001-0918-z
Herbert, 1997, Acetyl-CoA carbnoxylase—a graminicide target site, Pestic. Sci., 50, 67, 10.1002/(SICI)1096-9063(199705)50:1<67::AID-PS552>3.0.CO;2-#
Hill, 2002, Toxoplasma gondii: transmission, diagnosis and prevention, Clin. Microbiol. Infect., 8, 634, 10.1046/j.1469-0691.2002.00485.x
Huang, 2002, Phylogenetic analysis of the acetyl-CoA carboxylase and 3-phosphoglycerate kinase loci in wheat and other grasses, Plant Mol. Biol., 48, 805, 10.1023/A:1014868320552
Incledon, 1997, Acetyl-coenzyme A carboxylase: quaternary structure and inhibition by graminicidal herbicides, Pestic. Biochem. Physiol., 57, 255, 10.1006/pest.1997.2279
Jelenska, 2001, Subcellular localization of acetyl-CoA carboxylase in the apicomplexan parasite Toxoplasma gondii, Proc. Natl Acad. Sci. USA, 98, 2723, 10.1073/pnas.051629998
Jelenska, 2002, The carboxyltransferase activity of the apicoplast acetyl-CoA carboxylase of Toxoplasma gondii is the target of aryloxyphenoxypropionate inhibitors, J. Biol. Chem., 277, 23208, 10.1074/jbc.M200455200
Joachimiak, 1997, Wheat cytosolic acetyl-CoA carboxylase complements an ACC1 null mutation in yeast, Proc. Natl Acad. Sci. USA, 94, 9990, 10.1073/pnas.94.18.9990
Jomaa, 1999, Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs, Science, 285, 1573, 10.1126/science.285.5433.1573
Joshi, 2003, Engineering of an active animal fatty acid synthase dimer with only one competent subunit, Chem. Biol., 10, 169, 10.1016/S1074-5521(03)00023-1
Kaasch, 2000, Targeting and subcellular localization of Toxoplasma gondii catalase. Identification of peroxisomes in an apicomplexan parasite, J. Biol. Chem., 275, 1112, 10.1074/jbc.275.2.1112
Kapoor, 2001, Kinetic determinants of the interaction of enoyl-ACP reductase from Plasmodium falciparum with its substrates and inhibitors, Biochem. Biophys. Res. Commun., 289, 832, 10.1006/bbrc.2001.6061
Kissinger, 2002, The Plasmodium genome database—designing and mining a eukaryotic genomics resource, Nature, 419, 490, 10.1038/419490a
Kissinger, 2003, ToxoDB: accessing the Toxoplasma gondii genome, Nucleic Acids Res., 31, 234, 10.1093/nar/gkg072
Kuhajda, 2000, Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology, Nutrition, 16, 202, 10.1016/S0899-9007(99)00266-X
Kuo, 2003, Targeting tuberculosis and malaria through inhibition of enoyl reductase: compound activity and structural data, J. Biol. Chem., 26, 26
Li, 2003, Gene discovery in the Apicomplexa as revealed by EST sequencing and assembly of a comparative gene database, Genome Res., 13, 443, 10.1101/gr.693203
Macreadie, 2000, Antimalarial drug development and new targets, Parasitol. Today, 16, 438, 10.1016/S0169-4758(00)01758-0
Marechal, 2002, Synthesis of chloroplast galactolipids in apicomplexan parasites, Eukaryot. Cell, 1, 653, 10.1128/EC.1.4.653-656.2002
Martin, 1998, Gene transfer to the nucleus and the evolution of chloroplasts, Nature, 393, 162, 10.1038/30234
McFadden, 2001, Resistance as a tool in the study of old and new drug targets in Toxoplasma, Drug Resist. Update, 4, 79, 10.1054/drup.2001.0184
McFadden, 1999, Apicomplexan plastids as drug targets, Trends Microbiol., 7, 328, 10.1016/S0966-842X(99)01547-4
McLeod, 2001, Triclosan inhibits the growth of Plasmodium falciparum and Toxoplasma gondii by inhibition of apicomplexan Fab I, Int. J. Parasitol., 31, 109, 10.1016/S0020-7519(01)00111-4
Munday, 1999, The regulation of acetyl-CoA carboxylase—a potential target for the action of hypolipidemic agents, Adv. Enzyme Regul., 39, 205, 10.1016/S0065-2571(98)00016-8
Neuhaus, 2000, Nonphotosynthetic metabolism in plastids, Annu. Rev. Plant Physiol. Mol. Biol., 51, 111, 10.1146/annurev.arplant.51.1.111
Nikolskaya, 1999, Herbicide sensitivity determinant of wheat plastid acetyl-CoA carboxylase is located in a 400-amino acid fragment of the carboxyltransferase domain, Proc. Natl Acad. Sci. USA, 96, 14647, 10.1073/pnas.96.25.14647
Perozzo, 2002, Structural elucidation of the specificity of the antibacterial agent triclosan for malarial enoyl acyl carrier protein reductase, J. Biol. Chem., 277, 13106, 10.1074/jbc.M112000200
Prigge, 2003, The initiating steps of a type II fatty acid synthase in Plasmodium falciparum are catalyzed by pfACP, pfMCAT, and pfKASIII, Biochemistry, 42, 1160, 10.1021/bi026847k
Ralph, 2001, The apicoplast as an antimalarial drug target, Drug Resist. Update, 4, 145, 10.1054/drup.2001.0205
Ridley, 2002, Medical need, scientific opportunity and the drive for antimalarial drugs, Nature, 415, 686, 10.1038/415686a
Roberts, 2003, Fatty acid and sterol metabolism: potential antimicrobial targets in apicomplexan and trypanosomatid parasitic protozoa, Mol. Biochem. Parasitol., 126, 129, 10.1016/S0166-6851(02)00280-3
Rock, 2002, Forty years of bacterial fatty acid synthesis, Biochem. Biophys. Res. Commun., 292, 1155, 10.1006/bbrc.2001.2022
Roos, 2002, Mining the Plasmodium genome database to define organellar function: what does the apicoplast do?, Philos. Trans. R. Soc. Lond. B Biol. Sci., 357, 35, 10.1098/rstb.2001.1047
Shaw, 2003, Cell invasion by Theileria sporozoites, Trends Parasitol., 19, 2, 10.1016/S1471-4922(02)00015-6
Sibley, 1997, Yeast as a model system to study drugs effective against apicomplexan proteins, Methods, 13, 190, 10.1006/meth.1997.0511
Surolia, 2001, Triclosan offers protection against blood stages of malaria by inhibiting enoyl-ACP reductase of Plasmodium falciparum, Nat. Med., 7, 167, 10.1038/84612
Tenter, 2002, The conceptual basis for a new classification of the coccidia, Int. J. Parasitol., 32, 595, 10.1016/S0020-7519(02)00021-8
van Dooren, 2002, Processing of an apicoplast leader sequence in Plasmodium falciparum and the identification of a putative leader cleavage enzyme, J. Biol. Chem., 277, 23612, 10.1074/jbc.M201748200
Vial, 2003, Phospholipids in parasitic protozoa, Mol. Biochem. Parasitol., 126, 143, 10.1016/S0166-6851(02)00281-5
Waller, 1998, Nuclear-encoded proteins target to the plastid in Toxoplasma gondii and Plasmodium falciparum, Proc. Natl Acad. Sci. USA, 95, 12352, 10.1073/pnas.95.21.12352
Waller, 2003, A type II pathway for fatty acid biosynthesis presents drug targets in Plasmodium falciparum, Antimicrob. Agents Chemother., 47, 297, 10.1128/AAC.47.1.297-301.2003
Waller, 2000, Protein trafficking to the plastid of Plasmodium falciparum is via the secretory pathway, EMBO J., 19, 1794, 10.1093/emboj/19.8.1794
Ward, 2002, Using small molecules to study big questions in cellular microbiology, Cell Microbiol., 4, 471, 10.1046/j.1462-5822.2002.00205.x
Waters, 2002, Functional characterization of the acyl carrier protein (PfACP) and beta-ketoacyl ACP synthase III (PfKASIII) from Plasmodium falciparum, Mol. Biochem. Parasitol., 123, 85, 10.1016/S0166-6851(02)00140-8
Wilson, 2002, Progress with parasite plastids, J. Mol. Biol., 319, 257, 10.1016/S0022-2836(02)00303-0
Zagnitko, 2001, An isoleucine/leucine residue in the carboxyltransferase domain of acetyl-CoA carboxylase is critical for interaction with aryloxyphenoxypropionate and cyclohexanedione inhibitors, Proc. Natl Acad. Sci. USA, 98, 6617, 10.1073/pnas.121172798
Zhang, 2003, Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase, Science, 299, 2064, 10.1126/science.1081366
Zhu, 2000, What is the phylogenetic position of Cryptosporidium?, Int. J. Syst. Evol. Microbiol., 50, 1673, 10.1099/00207713-50-4-1673
Zhu, 2000, Cryptosporidium parvum appears to lack a plastid genome, Microbiology-UK, 146, 315, 10.1099/00221287-146-2-315
Zuegge, 2001, Deciphering apicoplast targeting signals—feature extraction from nuclear-encoded precursors of Plasmodium falciparum apicoplast proteins, Gene, 280, 19, 10.1016/S0378-1119(01)00776-4
Zuther, 1999, Growth of Toxoplasma gondii is inhibited by aryloxyphenoxypropionate herbicides targeting acetyl-CoA carboxylase, Proc. Natl Acad. Sci. USA, 96, 13387, 10.1073/pnas.96.23.13387