Apical Hypertrophic Cardiomyopathy in Childhood: A Long-Term Follow-Up Report of Two Cases

Pediatric Cardiology - Tập 30 - Trang 343-346 - 2008
Tomoyuki Miyamoto1, Hitoshi Horigome1, Satoru Kawano2, Ryo Sumazaki1
1Department of Child Health, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan
2Division of Cardiology, Department of Internal Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan

Tóm tắt

We present two children with apical hypertrophic cardiomyopathy (APH), both of whom remained asymptomatic for more than 15 years. The inverted T-wave on electrocardiograms and myocardial hypertrophy mostly confined to the apical region on echocardiograms showed no significant changes during follow-up. Magnetic resonance imaging revealed a cavitylike portion at the apex in one case, but the diagnosis of noncompacted myocardium was unlikely because there was no blood communication with the true left ventricular cavity. The other case had typically thick and solid myocardium at the apex. The findings in these patients demonstrate that APH might present in childhood and suggest that the prognosis might be good.

Tài liệu tham khảo

Choi EY, Rim SJ, Ha JW et al (2008) Phenotypic spectrum and clinical characteristics of apical hypertrophic cardiomyopathy: multicenter echo-Doppler study. Cardiology 110:53–61 Koga Y, Katoh A, Matsuyama K et al (1995) Disappearance of giant negative T waves in patients with the Japanese form of apical hypertrophy. J Am Coll Cardiol 26:1672–1678 Matsubara K, Nakamura T, Kuribayashi T, Azuma A, Nakagawa M (2003) Sustained cavity obliteration and apical aneurysm formation in apical hypertrophic cardiomyopathy. J Am Coll Cardiol 42:288–295 Nakamura T, Furukawa K, Matsubara K (1990) Long-term follow-up of electrocardiographic changes in patients with asymmetric apical hypertrophy. J Cardiol 20:635–647 Sakamoto T (2001) Apical hypertrophic cardiomyopathy (apical hypertrophy): an overview. J Cardiol 37(Suppl I):161–178 Sakamoto T, Tei C, Murayama M, Ichiyasu H, Hada Y, Hayashi T (1976) Giant T wave inversion as a manifestation of asymmetrical apical hypertrophy (AAH) of the left ventricle. Jpn Heart J 17:611–629 Webb JG, Sasson Z, Rakowski H, Peter L, Wigle ED (1990) Apical hypertrophic cardiomyopathy: clinical follow-up and diagnosis correlates. J Am Coll Cardiol 15:83–90 Yamaguchi H, Ishimura T, Nishiyama S et al (1979) Hypertrophic nonobstructive cardiomyopathy with giant negative T waves (apical hypertrophy): ventriculographic and echocardiographic features in 30 patients. Am J Cardiol 44:401–412