Aortic stiffness is independently associated with interstitial myocardial fibrosis by native T1 and accelerated in the presence of chronic kidney disease

Gross, 2008, Hypertrophy and fibrosis in the cardiomyopathy of uremia—beyond coronary heart disease, Semin. Dial., 21, 308, 10.1111/j.1525-139X.2008.00454.x Mangion, 2018, Characterizing cardiac involvement in chronic kidney disease using CMR-a systematic review, Curr. Cardiovasc. Imaging Rep., 11, 2, 10.1007/s12410-018-9441-9 Tonelli, 2006, Chronic kidney disease and mortality risk: a systematic review, J. Am. Soc. Nephrol., 17, 2034, 10.1681/ASN.2005101085 Adenwalla, 2017, The importance of accurate measurement of aortic stiffness in patients with chronic kidney disease and end-stage renal disease, Clin. Kidney J., 10, 503, 10.1093/ckj/sfx028 Karras, 2012, Large artery stiffening and remodeling are independently associated with all-cause mortality and cardiovascular events in chronic kidney disease, Hypertension., 60, 1451, 10.1161/HYPERTENSIONAHA.112.197210 Verbeke, 2011, Aortic stiffness and central wave reflections predict outcome in renal transplant recipients, Hypertension., 58, 833, 10.1161/HYPERTENSIONAHA.111.176594 Chirinos, 2012, Arterial wave reflections and incident cardiovascular events and heart failure: MESA (Multiethnic Study of Atherosclerosis), J. Am. Coll. Cardiol., 60, 2170, 10.1016/j.jacc.2012.07.054 Redheuil, 2014, Proximal aortic distensibility is an independent predictor of all-cause mortality and incident CV events: the MESA study, J. Am. Coll. Cardiol., 64, 2619, 10.1016/j.jacc.2014.09.060 Ohyama, 2016, Association of aortic stiffness with left ventricular remodeling and reduced left ventricular function measured by magnetic resonance imaging clinical perspective, Circ. Cardiovasc. Imaging, 9, 10.1161/CIRCIMAGING.115.004426 Bonapace, 2006, Aortic stiffness correlates with an increased extracellular matrix turnover in patients with dilated cardiomyopathy, Am. Heart J., 152, 10.1016/j.ahj.2006.04.026 Puntmann, 2014, Aortic stiffness and interstitial myocardial fibrosis by native T1 are independently associated with left ventricular remodeling in patients with dilated cardiomyopathy, Hypertension., 64, 762, 10.1161/HYPERTENSIONAHA.114.03928 Child, 2017, Comparison of MOLLI, shMOLLLI, and SASHA in discrimination between health and disease and relationship with histologically derived collagen volume fraction, Eur. Heart J. Cardiovasc. Imaging, 119, 277 Puntmann, 2016, T1-mapping and outcome in nonischemic cardiomyopathy, JACC Cardiovasc. Imaging, 9, 40, 10.1016/j.jcmg.2015.12.001 Puntmann, 2018, International T1 Multicentre CMR Outcome Study. Native T1 and ECV of noninfarcted myocardium and outcome in patients with coronary artery disease, J. Am. Coll. Cardiol., 71, 766, 10.1016/j.jacc.2017.12.020 Lee, 2018, Noncontrast myocardial T1 mapping by cardiac magnetic resonance predicts outcome in patients with aortic stenosis, JACC Cardiovasc. Imaging, 11, 974, 10.1016/j.jcmg.2017.09.005 Rogers, 2013, Standardization of T1 measurements with MOLLI in differentiation between health and disease – the ConSept study, J. Cardiovasc. Magn. Reson., 15, 78, 10.1186/1532-429X-15-78 Dabir, 2014, Reference values for healthy human myocardium using a T1 mapping methodology: results from the International T1 Multicenter cardiovascular magnetic resonance study, J. Cardiovasc. Magn. Reson., 16, 34, 10.1186/s12968-014-0069-x https://www.nice.org.uk/guidance/cg182 (last accessed March 1st, 2019). https://renal.org/information-resources/the-uk-eckd-guide/ckd-stages/ (last accessed March 1st 2019). 2016 European Guidelines on cardiovascular disease prevention in clinical practice. 2016;:1–78. Piepoli MF, Hoes AW, Agewall S, Albus C, Brotons C, Catapano AL, Cooney MT, Corrà U, Cosyns B, Deaton C, Graham I, Hall MS, Hobbs FDR, Løchen ML, Löllgen H, Marques-Vidal P, Perk J, Prescott E, Redon J, Richter DJ, Sattar N, Smulders Y, Tiberi M, van der Worp HB, van Dis I, Verschuren WMM, Binno S. 2016 European Guidelines on cardiovascular disease prevention in clinical practice: The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice. Eur Heart J.. 2016;37(29):2315–2381. Reiter, 2012, Minimizing risk of nephrogenic systemic fibrosis in cardiovascular magnetic resonance, J. Cardiovasc. Magn. Reson., 14, 31, 10.1186/1532-429X-14-31 http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/referrals/Gadolinium-containing_contrast_agents/human_referral_prac_000056.jsp&mid=WC0b01ac05805c516f (last accessed March 1st 2019). Hussain, 2012, Design and rationale of the MR-INFORM study: stress perfusion cardiovascular magnetic resonance imaging to guide the management of patients with stable coronary artery disease, J. Cardiovasc. Magn. Reson., 14, 65, 10.1186/1532-429X-14-65 Task Force Members, 2013, 2013 ESC guidelines on the management of stable coronary artery disease: the task force on the management of stable coronary artery disease of the European society of cardiology, Eur. Heart J., 34, 2949, 10.1093/eurheartj/eht296 Puntmann, 2018, Society for Cardiovascular Magnetic Resonance (SCMR) expert consensus for CMR imaging endpoints in clinical research: part I - analytical validation and clinical qualification, J. Cardiovasc. Magn. Reson., 20, 67, 10.1186/s12968-018-0484-5 Schulz-Menger, 2013, Standardized image interpretation and post processing in cardiovascular magnetic resonance: Society for Cardiovascular Magnetic Resonance (SCMR) Board of Trustees Task Force on Standardized Post Processing, J. Cardiovasc. Magn. Reson., 15, 35, 10.1186/1532-429X-15-35 Rutherford, 2016, Defining myocardial tissue abnormalities in end-stage renal failure with cardiac magnetic resonance imaging using native T1 mapping, Kidney Int., 90, 845, 10.1016/j.kint.2016.06.014 Graham-Brown, 2017, Native T1 mapping: inter-study, inter-observer and inter-center reproducibility in hemodialysis patients, J. Cardiovasc. Magn. Reson., 19, 21, 10.1186/s12968-017-0337-7 Edwards, 2015, Diffuse interstitial fibrosis and myocardial dysfunction in early chronic kidney disease, Am. J. Cardiol., 115, 1311, 10.1016/j.amjcard.2015.02.015 Peterson, 2013, Relationship of left ventricular hypertrophy and diastolic function with cardiovascular and renal outcomes in African Americans with hypertensive chronic kidney disease, Hypertension., 62, 518, 10.1161/HYPERTENSIONAHA.111.00904 Mark, 2008, Vascular function assessed with cardiovascular magnetic resonance predicts survival in patients with advanced chronic kidney disease, J. Cardiovasc. Magn. Reson., 10, 39, 10.1186/1532-429X-10-39 Redheuil, 2011, Age-related changes in aortic arch geometry: relationship with proximal aortic function and left ventricular mass and remodeling, J. Am. Coll. Cardiol., 58, 1262, 10.1016/j.jacc.2011.06.012 Redheuil, 2010, Reduced ascending aortic strain and distensibility: earliest manifestations of vascular aging in humans, Hypertension., 55, 319, 10.1161/HYPERTENSIONAHA.109.141275 Borlaug, 2008, Ventricular–vascular interaction in heart failure, Heart Fail. Clin., 4, 23, 10.1016/j.hfc.2007.10.001 Chemla, 1998, Total arterial compliance estimated by stroke volume-to-aortic pulse pressure ratio in humans, Am. J. Phys., 274, H500 Puntmann, 2012, Gender-specific differences in myocardial deformation and aortic stiffness at rest and Dobutamine stress, Hypertension., 59, 712, 10.1161/HYPERTENSIONAHA.111.183335 Piechnik, 2013, Normal variation of magnetic resonance T1 relaxation times in the human population at 1.5 T using ShMOLLI, J. Cardiovasc. Magn. Reson., 15, 13, 10.1186/1532-429X-15-13 Ugander, 2012, Extracellular volume imaging by magnetic resonance imaging provides insights into overt and sub-clinical myocardial pathology, Eur. Heart J., 33, 1268, 10.1093/eurheartj/ehr481 Liu, 2013, Evaluation of age-related interstitial myocardial fibrosis with cardiac magnetic resonance contrast-enhanced T1 mapping, J. Am. Coll. Cardiol., 62, 1280, 10.1016/j.jacc.2013.05.078 Hinojar, 2015, T1 mapping in discrimination of hypertrophic phenotypes: hypertensive heart disease and hypertrophic cardiomyopathy, Circ. Cardiovasc. Imaging, 8, 10.1161/CIRCIMAGING.115.003285 Dorn, 2007, The fuzzy logic of physiological cardiac hypertrophy, Hypertension., 49, 962, 10.1161/HYPERTENSIONAHA.106.079426 Turkbey, 2013, Aortic distensibility in type 1 diabetes, Diabetes Care, 36, 2380, 10.2337/dc12-0393 Karp, 2016, Assessment of aortic stiffness among patients with systemic lupus erythematosus and rheumatoid arthritis by magnetic resonance imaging, Int. J. Card. Imaging, 32, 935, 10.1007/s10554-016-0851-y Dickhout, 2011, Interrelationship between cardiac hypertrophy, heart failure, and chronic kidney disease: endoplasmic reticulum stress as a mediator of pathogenesis, Circ. Res., 108, 629, 10.1161/CIRCRESAHA.110.226803 Franssen, 2013, Nat. Rev. Nephrol., 9, 190, 10.1038/nrneph.2013.39 Borlaug, 2010, Exercise hemodynamics enhance diagnosis of early heart failure with preserved ejection fraction, Circ. Heart Fail., 3, 588, 10.1161/CIRCHEARTFAILURE.109.930701 Puntmann, 2016, T1 mapping in characterizing myocardial disease, Circ. Res., 119, 277, 10.1161/CIRCRESAHA.116.307974 Higgins, 2014, Review of T1 mapping methods: comparative effectiveness including reproducibility issues, Curr. Cardiovasc. Imaging Rep., 7, 9252, 10.1007/s12410-013-9252-y Cameron, 2017, Towards accurate and precise T 1 and extracellular volume mapping in the myocardium: a guide to current pitfalls and their solutions, MAGMA., 52, 1