Aortic Valve Replacement in a Patient With the Prothrombin 20210A Mutation

Poort, 1996, A common genetic variation in the 3’-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis, Blood, 88, 3968, 10.1182/blood.V88.10.3698.bloodjournal88103698 Kapur, 1997, A prothrombin gene mutation is significantly associated with venous thrombosis, Arterioscler Thromb Vasc Biol, 17, 2875, 10.1161/01.ATV.17.11.2875 Jafri, 2004, Periprocedural management of anticoagulation in patients on extended warfarin therapy, Semin Thromb Hemost, 30, 657, 10.1055/s-2004-861508 Jafri, 2004, Periprocedural thromboprophylaxis in patients receiving chronic anticoagulation therapy, Am Heart J, 147, 3, 10.1016/j.ahj.2003.06.001 Morris, 2001, Warfarin therapy does not increase bleeding in patients undergoing heart transplantation, Ann Thorac Surg, 72, 714, 10.1016/S0003-4975(01)02828-4 Fanashawe, 2001, Two cases of fatal thrombosis after aminocaproic acid therapy and deep hypothermic circulatory arrest, Anesthesiology, 95, 1525, 10.1097/00000542-200112000-00038 Donahue, 2003, Factor V Leiden protects against blood loss and transfusion after cardiac surgery, Circulation, 107, 1003, 10.1161/01.CIR.0000051864.28048.01 Despotis, 1997, Antithrombin III during cardiac surgery: effect on response of activated clotting time to heparin and relationship to markers of hemostatic activation, Anesth Analg, 85, 498, 10.1213/00000539-199709000-00005