Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: A novel test of anxiety in the rat

Pharmacology Biochemistry and Behavior - Tập 24 Số 3 - Trang 525-529 - 1986
Sharon Pellow1, Sandra E. File1
1MRC Neuropharmacology Research Group, Department of Pharmacology, The School of Pharmacy, University of London, 29-39 Brunswick Square, London WC1N 1AX, UK

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Braestrup, 1980, Urinary and brain ß-carboline-3-carboxylates as potent inhibitors of brain benzodiazepine receptors, 77, 2288

Dorow, 1983, Severe anxiety induced by FG 7142, a ß-carboline ligand for benzodiazepine receptors, Lancet, 9, 98, 10.1016/S0140-6736(83)90076-4

File, 1982, Animal anxiety and the effects of benzodiazepines, 355

File, 1985, Animal models for predicting clinical efficacy of anxiolytic drugs: Social behaviour, Neuropsychobiology, 13, 55, 10.1159/000118163

File, 1983, Quinolines and anxiety: anxiogenic effects of CGS 8216 and partial anxiolytic profile of PK 9084, Pharmacol Biochem Behav, 18, 185, 10.1016/0091-3057(83)90361-1

File, 1983, The anxiogenic action of Ro 5-4864 is reversed by phenytoin, Neurosci Lett, 39, 91, 10.1016/0304-3940(83)90170-2

File, 1982, Anxiogenic actions of benzodiazepine antagonists, Neuropharmacology, 21, 1033, 10.1016/0028-3908(82)90118-6

File, 1984, The anxiogenic action of FG 7142 in the social interaction test is reversed by chlordiazepoxide and Ro 15-1788 but not by CGS 8216, Arch Int Pharmacodyn Ther, 271, 198

File, 1985, The anxiolytic but not the sedative properties of tracazolate are reversed by the benzodiazepine receptor antagonist, Ro 15-1788, Neuropsychobiology, 10.1159/000118226

File, 1985, The benzodiazepine receptor antagonist Ro 15-1788 has an anxiogenic action in four animal tests of anxiety, Br J Pharmacol, 84, 104P

File, 1985, Intrinsic actions of the benzodiazepine receptor antagonist Ro 15-1788: A review, Psychopharmacology (Berlin)

File, 1986, Do the intrinsic actions of benzodiazepine receptor antagonists imply the existence of an endogenous ligand for the benzodiazepine receptor?

File, 1984, Interactions of two phenyl-quinolines with picrotoxin and benzodiazepines in vivo and in vitro, Eur J Pharmacol, 97, 295, 10.1016/0014-2999(84)90463-1

Hunkeler, 1981, Selective antagonists of benzodiazepines, Nature, 290, 514, 10.1038/290514a0

Jensen, 1984, Evaluation of the ß-carboline ZK 93426 as a benzodiazepine receptor antagonist, Psychopharmacology (Berlin), 83, 249, 10.1007/BF00464789

Keane, 1984, The quinolines PK 8165 and PK 9084 possess benzodiazepine-like activity in vitro but not in vitro, Neurosci Lett, 45, 89, 10.1016/0304-3940(84)90334-3

Le Fur, 1981, Multiple benzodiazepine receptors: evidence of a dissociation between anticonflict and anticonvulsant properties by PK 8165 and PK 9084 (two quinoline derivatives), Life Sci, 28, 1439, 10.1016/0024-3205(81)90375-1

Lippa, 1979, A synthetic non-benzodiazepine ligand for benzodiazepine receptors: A probe for investigating neuronal substrates of anxiety, Pharmacol Biochem Behav, 11, 99, 10.1016/0091-3057(79)90304-6

Meiners, 1982, Enhancement of benzodiazepine and GABA binding by the novel anxiolytic, tracazolate, Eur J Pharmacol, 78, 315, 10.1016/0014-2999(82)90033-4

Olsen, 1982, Drug interactions at the GABA receptorionophore complex, Annu Rev Pharmacol Toxicol, 22, 245, 10.1146/annurev.pa.22.040182.001333

Patel, 1982, Pharmacological properties of tracazolate: a new non-benzodiazepine anxiolytic agent, Eur J Pharmacol, 78, 323, 10.1016/0014-2999(82)90034-6

Pellow, 1985, Can drug effects on anxiety and convulsions be separated?, Neurosci Biobehav Rev, 9, 55, 10.1016/0149-7634(85)90032-6

Pellow, 1985, Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat, J Neurosci Methods, 14, 149, 10.1016/0165-0270(85)90031-7

Pellow, 1984, Multiple sites of action for anxiogenic drugs: behavioural, electrophysiological and biochemical correlations, Psychopharmacology (Berlin), 83, 304, 10.1007/BF00428536

Pellow, 1984, Characteristics of an atypical benzodiazepine, Ro 5-4864, Neurosci Biobehav Rev, 8, 405, 10.1016/0149-7634(84)90060-5

Pellow, 1985, Is tofisopam an atypical anxiolytic?, Neurosci Biobehav Rev

Pellow, 1985, Effects of tofisopam, a 3,4-benzodiazepine, on anxiety, sedation and convulsions in rodents, Drugs Dev Res

Petersen, 1983, Differential pharmacological effects of benzodiazepine receptor inverse agonists, vol. 38, 57

Taylor, 1984, Changing concepts of the biochemical action of the anxioselective drug, buspirone, Drug Dev Res, 4, 95, 10.1002/ddr.430040111

Yokoyama, 1982, 2-Arylpyrazolo 4,3-cquinolin-3-ones: novel agonist, partial agonist and antagonist of benzodiazepines, J Med Chem, 25, 337, 10.1021/jm00346a002