Antiviral Agents

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that of acyclovir against human, monkey, and rodent cytomegaloviruses, Antimicrob Agents Chemother, 28, 240, 10.1128/AAC.28.2.240 Field, 1983, 9-{[2-Hydroxy-1-(hydroxymethyl)ethoxy]-methyl}guanine: a selective inhibitor of herpes group virus replication, Proc Natl Acad Sci U S A, 80, 4139, 10.1073/pnas.80.13.4139 Frank, 1984, Interaction of herpes simplex virus-induced DNA polymerase with 9-(1,3-dihydroxy-2-propoxymethyl)guanine triphosphate, J Biol Chem, 259, 1566, 10.1016/S0021-9258(17)43446-6 Clair, 1984, Inhibition of cellular α DNA polymerase and herpes simplex virus-induced DNA polymerases by the triphosphate of BW759U, Antimicrob Agents Chemother, 25, 191, 10.1128/AAC.25.2.191 Prusoff, 1985, Basic biochemical and pharmacological aspects of antiviral agents, Antiviral Res Suppl, 1, 1, 10.1016/S0166-3542(85)80002-4 Furman, 1986, Phosphorylation of 3′-azido-3′-deoxythymidine and selective interaction of the 5′-triphosphate with human immunodeficiency virus reverse transcriptase, 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10.1128/AAC.11.6.946 Wray, 1985, Effect of ribavirin triphosphate on primer generation and elongation during influenza virus transcription in vitro, Antiviral Res, 5, 39, 10.1016/0166-3542(85)90013-0 Couch, 1986, The antiviral spectrum and mechanism of action of amantadine and rimantadine, 50 Pagano, 1982, Perspectives on interactions of acyclovir with Epstein-Barr and other herpes viruses, Am J Med, 73, 18, 10.1016/0002-9343(82)90057-2 Wade, 1982, Treatment of cytomegalovirus pneumonia with high-dose acyclovir, Am J Med, 73, 249, 10.1016/0002-9343(82)90100-0 Burns, 1990, Susceptibility of human herpesvirus 6 to antivirals in vitro, J Infect Dis, 162, 634, 10.1093/infdis/162.3.634 Keeney, 1982, Acyclovir tolerance in humans, Am J Med, 73, 176, 10.1016/0002-9343(82)90086-9 Bean, 1985, Adverse effects of high-dose intravenous acyclovir in ambulatory patients with acute herpes zoster, J Infect Dis, 151, 362, 10.1093/infdis/151.2.362 Balfour, 1989, A randomized, placebo-controlled trial of oral acyclovir for the prevention of cytomegalovirus disease in recipients of renal allografts, N Engl J Med, 320, 1381, 10.1056/NEJM198905253202105 Bryson, 1983, Treatment of first episodes of genital herpes simplex virus infection with oral acyclovir: a randomized double-blind controlled trial in normal subjects, N Engl J Med, 308, 916, 10.1056/NEJM198304213081602 Nilsen, 1982, Efficacy of oral acyclovir in the treatment of initial and recurrent genital herpes, Lancet, 2, 571, 10.1016/S0140-6736(82)90658-4 Ruhnek-Forsbeck, 1985, Treatment of recurrent genital herpes simplex infections with oral acyclovir, J Antimicrob Chemother, 16, 621, 10.1093/jac/16.5.621 Reichman, 1984, Treatment of recurrent genital herpes simplex infections with oral acyclovir: a controlled trial, JAMA, 251, 2103, 10.1001/jama.1984.03340400031020 Corey, 1982, A trial of topical acyclovir in genital herpes simplex virus infections, N Engl J Med, 306, 1313, 10.1056/NEJM198206033062201 Reichman, 1983, Topically administered acyclovir in the treatment of recurrent herpes simplex genitalis: a controlled trial, J Infect Dis, 147, 336, 10.1093/infdis/147.2.336 Luby, 1984, A collaborative study of patient-initiated treatment of recurrent genital herpes with topical acyclovir or placebo, J Infect Dis, 150, 1, 10.1093/infdis/150.1.1 Corey, 1983, Intravenous acyclovir for the treatment of primary genital herpes, Ann Intern Med, 98, 914, 10.7326/0003-4819-98-6-914 Straus, 1984, Suppression of frequently recurring genital herpes: a placebo-controlled double-blind trial of oral acyclovir, N Engl J Med, 310, 1545, 10.1056/NEJM198406143102401 Douglas, 1984, A double-blind study of oral acyclovir for suppression of recurrences of genital herpes simplex virus infection, N Engl J Med, 310, 1551, 10.1056/NEJM198406143102402 Mertz, 1988, Prolonged continuous versus intermittent oral acyclovir treatment in normal adults with frequently recurring genital herpes simplex virus infection, Am J Med, 85, 14 Mostow, 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Antimicrob Agents Chemother, 31, 361, 10.1128/AAC.31.3.361 Balfour, 1983, Acyclovir halts progression of herpes zoster in immunocompromised patients, N Engl J Med, 308, 1448, 10.1056/NEJM198306163082404 Shepp, 1986, Treatment of varicella-zoster virus infection in severely immunocompromised patients: a randomized comparison of acyclovir and vidarabine, N Engl J Med, 314, 208, 10.1056/NEJM198601233140404 Balfour, 1984, Intravenous acyclovir therapy for varicella in immunocompromised children, J Pediatr, 104, 134, 10.1016/S0022-3476(84)80611-3 Nyerges, 1988, Acyclovir prevents dissemination of varicella in immunocompromised children, J Infect Dis, 157, 309, 10.1093/infdis/157.2.309 Cobo, 1986, Oral acyclovir in the treatment of acute herpes zoster ophthalmicus, Ophthalmology, 93, 763, 10.1016/S0161-6420(86)33678-9 Cobo, 1988, Reduction of the ocular complications of herpes zoster ophthalmicus by oral acyclovir, Am J Med, 85, 90 McKendrick, 1986, Oral acyclovir in acute herpes zoster, Br 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Intern Med, 100, 823, 10.7326/0003-4819-100-6-823 Seale, 1985, Prevention of herpesvirus infections in renal allograft recipients by low-dose oral acyclovir, JAMA, 254, 3435, 10.1001/jama.1985.03360240047032 Resnick, 1988, Regression of oral hairy leukoplakia after orally administered acyclovir therapy, JAMA, 259, 384, 10.1001/jama.1988.03720030044031 Andersson, 1986, Effect of acyclovir on infectious mononucleosis: a double-blind, placebo-controlled study, J Infect Dis, 153, 283, 10.1093/infdis/153.2.283 Dummer, 1984, Epstein-Barr virus-induced lymphoma in a cardiac transplant recipient, Am J Med, 77, 179, 10.1016/0002-9343(84)90458-3 Sullivan, 1984, Epstein-Barr-virus induced lymphoproliferation: implications for antiviral chemotherapy, N Engl J Med, 311, 1163, 10.1056/NEJM198411013111806 Gamier, 1989, Epstein-Barr virus associated lymphoproliferative diseases (B cell lymphoma) after transplantation, Nephrol Dial Transplant, 4, 818 Straus, 1988, Acyclovir treatment of the chronic fatigue syndrome: lack of efficacy in a placebo-controlled trial, N Engl J Med, 319, 1692, 10.1056/NEJM198812293192602 Saks, 1989 Erice, 1987, Ganciclovir treatment of cytomegalovirus disease in transplant recipients and other immunocompromised hosts, JAMA, 257, 3082, 10.1001/jama.1987.03390220080025 Hochster, 1990, Toxicity of combined ganciclovir and zidovudine for cytomegalovirus disease associated with AIDS: an AIDS clinical trials group study, Ann Intern Med, 113, 111, 10.7326/0003-4819-113-2-111 Follansbee, 1990, Phase I study of the safety and pharmacokinetics of oral ganciclovir (abstract FB91) Jabs, 1989, Cytomegalovirus retinitis and acquired immunodeficiency syndrome, Arch Ophthalmol, 107, 75, 10.1001/archopht.1989.01070010077031 Orellana, 1987, Combined short- and long-term therapy for the treatment of cytomegalovirus retinitis using ganciclovir (BW B759U), Ophthalmology, 94, 831, 10.1016/S0161-6420(87)33536-5 Jacobson, 1988, Randomized prospective trial of ganciclovir 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Cytomegalovirus pneumonia after bone marrow transplantation successfully treated with the combination of ganciclovir and high-dose intravenous immune globulin, Ann Intern Med, 109, 777, 10.7326/0003-4819-109-10-777 Reed, 1988, Treatment of cytomegalovirus pneumonia with ganciclovir and intravenous cytomegalovirus immunoglobulin in patients with bone marrow transplants, Ann Intern Med, 109, 783, 10.7326/0003-4819-109-10-783 Paya, 1989, Cytomegalovirus hepatitis in liver transplantation: prospective analysis of 93 consecutive orthotopic liver transplantations, J Infect Dis, 160, 752, 10.1093/infdis/160.5.752 Wreghitt, 1989, Cytomegalovirus infections in heart and heart-lung transplant recipients, J Antimicrob Chemother, 23, 49, 10.1093/jac/23.suppl_E.49 Schmidt, 1991, A randomized, controlled trial of prophylactic ganciclovir for cytomegalovirus pulmonary infection in recipients of allogeneic bone marrow transplants, N Engl J Med, 324, 1005, 10.1056/NEJM199104113241501 Laske, 1991, 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San Francisco, Aug 19 to 24, 1990 Freise, 1991, Comparison of three regimens for cytomegalovirus prophylaxis in 147 liver transplant recipients, Transplant Proc, 23, 1498 Kirsi, 1983, Broad-spectrum antiviral activity of 2-β-d-ribofuranosylselenazole-4-carboxamide, a new antiviral agent, Antimicrob Agents Chemother, 24, 353, 10.1128/AAC.24.3.353 Hall, 1983, Aerosolized ribavirin treatment of infants with respiratory syncytial viral infection: a randomized double-blind study, N Engl J Med, 308, 1443, 10.1056/NEJM198306163082403 Hall, 1985, Ribavirin treatment of respiratory syncytial viral infection in infants with underlying cardiopulmonary disease, JAMA, 254, 3047, 10.1001/jama.1985.03360210063030 Englund, 1990, High-dose, short-duration ribavirin aerosol therapy in children with suspected respiratory syncytial virus infection, J Pediatr, 117, 313, 10.1016/S0022-3476(05)80554-2 Hicks, 1986, Precipitation of ribavirin causing obstruction of a ventilation tube, Pediatr Infect Dis J, 5, 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10.1128/AAC.31.8.1285 Bernstein, 1988, Ribavirin small-particle-aerosol treatment of influenza B virus infection, Antimicrob Agents Chemother, 32, 761, 10.1128/AAC.32.5.761 Peigue-Lafeuille, 1990, Severe respiratory syncytial virus pneumonia in an adult renal transplant recipient: successful treatment with ribavirin, Scand J Infect Dis, 22, 87, 10.3109/00365549009023124 Hertz, 1989, Respiratory syncytial virus-induced acute lung injury in adult patients with bone marrow transplants: a clinical approach and review of the literature, Medicine, 68, 269, 10.1097/00005792-198909000-00002 Broder, 1990, Antiretroviral therapy in AIDS, Ann Intern Med, 113, 604, 10.7326/0003-4819-113-8-604 Hirsch, 1988, AIDS commentary: azidothymidine, J Infect Dis, 157, 427, 10.1093/infdis/157.3.427 Richman, 1987, The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex: a double-blind, placebo-controlled trial, N Engl J Med, 317, 192, 10.1056/NEJM198707233170402 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