Antitumor and immunomodulatory effects of weikangfu granule compound in tumor-bearing mice

Zee-Cheng, 1992, Shi-quan-da-bu-tang (ten significant tonic decoction), SQT. A potent Chinese biological response modifier in cancer immunotherapy, potentiation and detoxification of anticancer drugs, Methods Find Exp Clin Pharmacol, 14, 725 Lee, 2003, Antimetastatic and immunomodulating properties of a new herbal prescription, Bojung-bangam-tang, Int Immunopharmacol, 3, 147, 10.1016/S1567-5769(02)00091-7 Ohnishi, 1998, Oral administration of a Kampo (Japanese herbal) medicine Juzen-taiho-to inhibits liver metastasis of colon 26-L5 carcinoma cells, Jpn J Cancer Res, 89, 206, 10.1111/j.1349-7006.1998.tb00550.x Saiki, 2000, A Kampo medicine “Juzen-taiho-to”—prevention of malignant progression and metastasis of tumor cells and the mechanism of action, Biol Pharm Bull, 23, 677, 10.1248/bpb.23.677 Ha, 2004, Inhibitory effect of Daesungki-Tang on the invasiveness potential of hepatocellular carcinoma through inhibition of matrix metalloproteinase-2 and -9 activities, Toxicol Appl Pharmacol, 200, 1, 10.1016/j.taap.2004.03.012 Zhang, 2003, Inhibition of cancer cell proliferation and prostaglandin E2 synthesis by Scutellaria baicalensis, Cancer Res, 63, 4037 Liu, 2002, Jolkinolide B induces neuroendocrine differentiation of human prostate LNCaP cancer cell line, Biochem Pharmacol, 63, 951, 10.1016/S0006-2952(01)00938-8 Yoo, 2005, Eugenol isolated from the essential oil of Eugenia caryophyllata induces a reactive oxygen species-mediated apoptosis in HL-60 human promyelocytic leukemia cells, Cancer Lett., 225, 41, 10.1016/j.canlet.2004.11.018 Yin, 1999, Curative effect of Weikangfu granule on gastric precancerosis, Chin J Integr Trad West Med on Gastro-Spleen, 7, 214 Yin, 2000, Effect of Weikangfu chongji on epithelial cellular ultrastructure of precancerotic gastric mucosa of patients with spleen deficiency syndrome, Jiangsu Med J, 26, 514 Yin, 2000, Therapeutic effect of weikangfu on gastric precancerous disorder with spleen deficiency syndrome and its effect on gastric mucosal zinc, copper, cyclic adenosine monophosphate, superoxide dismutase, lipid peroxide and 3H-TdR lymphocyte conversion test, Zhongguo Zhong Xi Yi Jie He Za Zhi, 20, 176 Yin, 2000, Effect of Weikangfu granule on ultrastructure of gastric mucosa in patients of precancerosis with spleen deficiency syndrome, Zhongguo Zhong Xi Yi Jie He Za Zhi, 20, 667 Yin, 2000, The effect of Weikangfu on cytopathology of gastric mucosa tissue when treating gastric precancerosis lesion of patients with spleen deficiency syndromes, Chin J Surgery Integr Trad West Med, 6, 241 Yin, 2000, Effect of Weikangfu on ZnCu and DNA in precancerosis gastric mucosa epithelial nuclei and mitochondria of patients with spleen deficiency syndromes, Chin J Integr Trad West Med on Gastro-Spleen, 8, 221 Zhou, 2004, In vivo antitumor and immunomodulation activities of different molecular weight lambda-carrageenans from Chondrus ocellatus, Pharmacol Res., 50, 47, 10.1016/j.phrs.2003.12.002 Yang, 2003, The pathology observation of antitumor effects of secondary metabolites of Rhizoctonia leguminicola, Acta Agric Boreali-occidentalis Sinica, 12, 5 Cheng, 2000 Mosmann, 1983, Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays, J Immunol Methods, 65, 55, 10.1016/0022-1759(83)90303-4 Gan, 2004, Immunomodulation and antitumor activity by a polysaccharide-protein complex from Lycium barbarum, Int Immunopharmacol, 4, 563, 10.1016/j.intimp.2004.01.023 Chen, 1994, Effects of Rehmannia glutinosa polysaccharide b on T lymphocyte function in normal and S180 tumor bearing mice, Chinese J Pharmacol Toxicol, 8, 125 Yin, 1997, 46 Sato, 2005, Histopathological and immunophenotyping studies on normal and sarcoma 180-bearing mice treated with a complex homeopathic medication, Homeopathy, 94, 26, 10.1016/j.homp.2004.10.003 Buchi Dde, 1993, Internalization of surface components during Fc-receptor mediated phagocytosis by macrophages, Cell Struct Funct, 18, 399, 10.1247/csf.18.399 Zheng, 2005, Characterization and immunomodulating activities of polysaccharide from Lentinus edodes, Int Immunopharmacol, 5, 811, 10.1016/j.intimp.2004.11.011 Han, 1999, The inhibitory effect of polysaccharides isolated from Phellinus linteus on tumor growth and metastasis, Immunopharmacology, 41, 157, 10.1016/S0162-3109(98)00063-0 Han, 1998, Characteristic immunostimulation by angelan isolated from Angelica gigas Nakai, Immunopharmacology, 40, 39, 10.1016/S0162-3109(98)00026-5 Klimp, 2002, A potential role of macrophage activation in the treatment of cancer, Crit Rev Oncol Hematol, 44, 143, 10.1016/S1040-8428(01)00203-7 Peters, 1996, Dendritic cells: From ontogenetic orphans to myelomonocytic descendants, Immunol Today, 17, 273, 10.1016/0167-5699(96)80544-5 Stuelp-Campelo, 2002, Effect of a soluble alpha-D-glucan from the lichenized fungus Ramalina celastri on macrophage activity, Int Immunopharmacol, 2, 691, 10.1016/S1567-5769(02)00003-6 Compton, 1996, The beneficial effect of enhanced macrophage function on the healing of bowel anastomoses, Am Surg., 62, 14 Qiu, 2000, Modified Aloe barbadensis polysaccharide with immunoregulatory activity, Planta Med., 66, 152, 10.1055/s-2000-11125