Antinuclear antibodies in healthy population: Positive association with abnormal tissue metabolism, inflammation and immune dysfunction

International Immunopharmacology - Tập 113 - Trang 109292 - 2022
Qinghong Ge1, Xiuyu Gu1, Wen Yu1, Guoping Zhang1, Wei Liang1, Meifen Li1, Guanghua Zhai1, Meina Yan1
1Department of Laboratory Medicine, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, 242 Guangji Road, Suzhou, Jiangsu 215008, PR China

Tài liệu tham khảo

Burbelo, 2021, Autoantibodies targeting intracellular and extracellular proteins in autoimmunity, Front. Immunol., 12, 10.3389/fimmu.2021.548469 Tešija Kuna, 2021, Assessment of antinuclear antibodies (ANA): National recommendations on behalf of the Croatian society of medical biochemistry and laboratory medicine, Biochem Med (Zagreb), 31, 10.11613/BM.2021.020502 Sur, 2018, Antinuclear antibodies: marker of diagnosis and evolution in autoimmune diseases, Lab. Med., 49, e62, 10.1093/labmed/lmy024 Pisetsky, 2019, ANA as an entry criterion for the classification of SLE, Autoimmun. Rev., 18, 10.1016/j.autrev.2019.102400 Bossuyt, 2020, Understanding and interpreting antinuclear antibody tests in systemic rheumatic diseases, Nat. Rev. Rheumatol., 16, 715, 10.1038/s41584-020-00522-w Ling, 2019, Antinuclear antibody tests, Clin. Lab. Med., 39, 513, 10.1016/j.cll.2019.07.001 Sudheer, 2021, Antinuclear antibodies in neurology and their clinical application, QJM, 10.1093/qjmed/hcab304 Solow, 2018, Antinuclear antibodies in the general population: positive association with inflammatory and vascular biomarkers but not traditional cardiovascular risk factors, Clin. Exp. Rheumatol., 36, 1031 Nunes, 2018, Prevalence of auto-antibodies associated to pulmonary arterial hypertension in scleroderma - A review, Autoimmun. Rev., 17, 1186, 10.1016/j.autrev.2018.06.009 Long, 2018, Dysregulation of microRNAs in autoimmune diseases: pathogenesis, biomarkers and potential therapeutic targets, Cancer Lett., 428, 90, 10.1016/j.canlet.2018.04.016 Meroni, 2014, Automated tests of ANA immunofluorescence as throughput autoantibody detection technology: strengths and limitations, BMC Med., 12, 38, 10.1186/1741-7015-12-38 Li, 2019, Epidemiological survey of antinuclear antibodies in healthy population and analysis of clinical characteristics of positive population, J. Clin. Lab. Anal., 33, e22965, 10.1002/jcla.22965 Chen, 2020, Beijing Da Xue Xue Bao Yi Xue Ban, 52, 886 Zi, 2018, Involvement of cystatin C in immunity and apoptosis, Immunol. Lett., 196, 80, 10.1016/j.imlet.2018.01.006 Xu, 2019, Diagnostic performance of serum cystatin C and complement component 1q in lupus nephritis, Arthritis Res. Ther., 21, 267, 10.1186/s13075-019-2065-x Zanatta, 2019, Inflammation and coronary microvascular dysfunction in autoimmune rheumatic diseases, Int. J. Mol. Sci., 20, 10.3390/ijms20225563 Pandolfi, 2020, Interleukin-6 in Rheumatoid Arthritis, Int. J. Mol. Sci., 21, 10.3390/ijms21155238 Kaur, 2020, A panoramic review of IL-6: Structure, pathophysiological roles and inhibitors, Bioorg. Med. Chem., 28, 10.1016/j.bmc.2020.115327 Tang, 2019, Changes of serum IL-6, IL-17, and complements in systemic lupus erythematosus patients, J. Interferon Cytokine Res.: The Off. J. Int. Soc. Interferon Cytokine Res., 39, 410, 10.1089/jir.2018.0169 A. Ogata, Y. Kato, IL-6 inhibitor for the treatment of rheumatoid arthritis: A comprehensive review2019; 29: 258-267. An, 2018, Enhanced neutrophil autophagy and increased concentrations of IL-6, IL-8, IL-10 and MCP-1 in rheumatoid arthritis, Int. Immunopharmacol., 65, 119, 10.1016/j.intimp.2018.09.011 Nilsson, 2019, Increased B-cell activating factor, interleukin-6, and interleukin-8 in induced sputum from primary Sjögren's syndrome patients, Scand. J. Rheumatol., 48, 149, 10.1080/03009742.2018.1473488 Yang, 2020, IL-8 mediates a positive loop connecting increased neutrophil extracellular traps (NETs) and colorectal cancer liver metastasis, J. Cancer, 11, 4384, 10.7150/jca.44215 Lee, 2017, Neutrophil extracellular traps (NETs) in autoimmune diseases: a comprehensive review, Autoimmun. Rev., 16, 1160, 10.1016/j.autrev.2017.09.012 Sørensen, 2016, Neutrophil extracellular traps - the dark side of neutrophils, J. Clin. Investig., 126, 1612, 10.1172/JCI84538 Deng, 2019, The emerging epigenetic role of CD8+T cells in autoimmune diseases: a systematic review, Front. Immunol., 10, 856, 10.3389/fimmu.2019.00856 Danikowski, 2017, Regulatory T cells in multiple sclerosis and myasthenia gravis, J. Neuroinflammation, 14, 117, 10.1186/s12974-017-0892-8 Kumar, 2019, Restoring self-tolerance in autoimmune diseases by enhancing regulatory T-cells, Cell. Immunol., 339, 41, 10.1016/j.cellimm.2018.09.008 Kucuksezer, 2021, The Role of Natural Killer Cells in Autoimmune Diseases, Front. Immunol., 12, 10.3389/fimmu.2021.622306 Chalan, 2016, Altered natural killer cell subsets in seropositive arthralgia and early rheumatoid arthritis are associated with autoantibody status, J Rheumatol, 43, 1008, 10.3899/jrheum.150644 Aggarwal, 2014, Role of cytolytic impairment of natural killer and natural killer T-cell populations in rheumatoid arthritis, Clin. Rheumatol., 33, 1067, 10.1007/s10067-014-2641-z Park, 2009, Impaired differentiation and cytotoxicity of natural killer cells in systemic lupus erythematosus, Arthritis Rheum., 60, 1753, 10.1002/art.24556 Riccieri, 2000, Down-regulation of natural killer cells and of gamma/delta T cells in systemic lupus erythematosus. does it correlate to autoimmunity and to laboratory indices of disease activity?, Lupus, 9, 333, 10.1191/096120300678828460 Salvi, 2019, Cytokine targeting by miRNAs in autoimmune diseases, Front. Immunol., 10, 15, 10.3389/fimmu.2019.00015 Nakhjavani, 2019, Plasma levels of miR-21, miR-150, miR-423 in patients with lupus nephritis, Iranian J. Kidney Dis., 13, 198 Ma, 2014, Expression, regulation and function of microRNAs in multiple sclerosis, Int. J. Medical Sci., 11, 810, 10.7150/ijms.8647 Wang, 2016, The MicroRNA-21 in autoimmune diseases, Int. J. Mol. Sci., 17 Taheri, 2020, Regulatory and immunomodulatory role of miR-34a in T cell immunity, Life Sci., 262, 10.1016/j.lfs.2020.118209 Xie, 2019, NF-κB-driven miR-34a impairs Treg/Th17 balance via targeting Foxp3, J. Autoimmun., 102, 96, 10.1016/j.jaut.2019.04.018 Ghadiri, 2018, Analysis of the expression of mir-34a, mir-199a, mir-30c and mir-19a in peripheral blood CD4+T lymphocytes of relapsing-remitting multiple sclerosis patients, Gene, 659, 109, 10.1016/j.gene.2018.03.035