Antidiabetic, antioxidant, molecular docking and HPTLC analysis of miquelianin isolated from Euphorbia schimperi C. Presl

Abdel-Monem, 2008, Chemical investigation of Euphorbia schimperi C, Presl. Rec. Nat. Prod., 2, 39 Ahmed, 2017, Activity guided isolation of chemical constituents from the biologically active methanol extract of Euphorbia schimperi c. presl, Bull. Chem. Soc. Ethiop., 31, 471, 10.4314/bcse.v31i3.11 Ahmed, 2016, Studies on wound healing activity of some Euphorbia species on experimental rats, Afr. J. Tradit. Complement. Altern. Med., 13, 45, 10.21010/ajtcam.v13i5.19 AL-Sultan, 2006, Acute toxicity of Euphorbia heliscopia in Rats, Pak. J. Nut., 5, 135, 10.3923/pjn.2006.135.140 Blois, 1958, Antioxidant determinations by the use of a stable free radical, Nature, 29, 1199, 10.1038/1811199a0 Bondet, 1997, Kinetics and mechanisms of antioxidant activity using the DPPH free radical method, Lebensm.-Wiss. u.-Technol., 30, 609, 10.1006/fstl.1997.0240 Braca, 2001, Antioxidant principles from Bauhinia tarapotensis, J. Nat. Prod., 64, 892, 10.1021/np0100845 Chaudhary, 2001 Deighton, 2000, Antioxidant properties of domesticated and wild Rubus species, J. Sci. Food Agric., 80, 1307, 10.1002/1097-0010(200007)80:9<1307::AID-JSFA638>3.0.CO;2-P Giner, 2015, Polygonifoliol, a new tirucallane triterpene from the latex of the seaside sandmat Euphorbia polygonifolia, Chem. Biodivers., 12, 1126, 10.1002/cbdv.201400426 Gupta, 2005, Hypoglycemicand anti-diabetic effect of ethanolic extract of leaves of Annona squamosa L. in experimental animals, J Ethnopharmacol., 99, 75, 10.1016/j.jep.2005.01.048 Harman, 1998, 3 International Conference on Harmonization (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human use, Harmonised Triplicate Guideline on Validation of Analytical Procedures: Text and Methodology Q2 (R1), Complementary Guideline on Methodology incorporated in November 2005 by the ICH Steering Committee, IFPMA, Geneva. Jassbi, 2006, Chemistry and biological activity of secondary metabolites in Euphorbia from Iran, Phytochemistry, 67, 1977, 10.1016/j.phytochem.2006.06.030 Kavishankar, 2011, Diabetes and medicinal plants: a review, Int. J. Pharm. Biomed. Sci., 2, 65 Kim, 2000, Inhibition of alpha-glucosidase and amylase by luteolin, a flavonoid, Biosci. Biotechnol. Biochem., 64, 2458, 10.1271/bbb.64.2458 Kwon, 2008, Inhibitory potential of wine and tea against α-amylase and α-glucosidase for management of hyperglycemia linked to type 2 diabetes, J. Food Biochem., 32, 15, 10.1111/j.1745-4514.2007.00165.x Mallavadhani, 2002, Quantitative estimation of an antidiarrhoeic marker in euphorbia hirta samples, Pharmaceut. Bio., 40, 103, 10.1076/phbi.40.2.103.5841 Maurus, 2008, Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity, Biochemistry, 47, 3332, 10.1021/bi701652t Morris, 2009, Autodock4 and AutoDockTools4: automated docking with selective receptor flexiblity, J. Comput. Chem., 16, 2785, 10.1002/jcc.21256 Mothana, 2009, Evaluation of the in vitro anticancer, antimicrobial and antioxidant activities of some Yemeni plants used in folk medicine, Die Pharmazie., 64, 260 Re, 1999, Antioxidant activity applying an improved ABTS radical cation decolorization assay, Free Radic. Biol. Med., 26, 1231, 10.1016/S0891-5849(98)00315-3 Rehman, 2016, Interaction of meropenem with 'N' and 'B' isoforms of human serum albumin: a spectroscopic and molecular docking study, J. Biomol. Struct. Dyn., 34, 1849, 10.1080/07391102.2015.1094411 Rehman, 2014, Insight into the binding mechanism of imipenem to human serum albumin by spectroscopic and computational approaches, Mol. Pharmaceut., 11, 1785, 10.1021/mp500116c Roig-Zamboni, 2017, Structure of human lysosomal acid α-glucosidase – a guide for the treatment of Pompe disease, Nat. Commun., 8, 1111, 10.1038/s41467-017-01263-3 Rydberg, 2002, Mechanistic analyses of catalysis in human pancreatic alpha-amylase: detailed kinetic and structural studies of mutants of three conserved carboxylic acids, Biochemistry, 41, 4492, 10.1021/bi011821z Shi, 2008, Chemical and pharmacological research of the plants in genus Euphorbia, Chem. Rev., 108, 4295, 10.1021/cr078350s Singh, 2014, Antidiabetic and wound healing activity of catharanthus roseus l. in streptozotocininduced diabetic mice, Am. J. Phytomed. Clin. Therapeut., 2, 686 Siddiqui, 2015, Simultaneous quantification of biomarkers bergenin and menisdaurin in the methanol extract of aerial parts of Flueggea virosa by validated HPTLC densitometric method, J. Chromatogr. Sci., 53, 824, 10.1093/chromsci/bmu231 Siddiqui, 2018, Concurrent analysis of bioactive triterpenes oleanolic acid and b-amyrin in antioxidant active fractions of Hibiscus calyphyllus, Hibiscus deflersii and Hibiscus micranthus grown in Saudi Arabia by applying validated HPTLC method, Saudi Pharmaceut. J., 26, 266, 10.1016/j.jsps.2017.11.013 Smara, 2014, Flavonoïds from Euphorbia guyoniana Boissier & Reuter, J. Life Sci., 8, 544 WHO, 1999 Wu, 2011, Evaluation of the antioxidant effects of four main theaflavin derivatives through chemiluminescence and DNA damage analyses, J. Zhejiang Univ. Sci. B, 12, 744, 10.1631/jzus.B1100041 Yamagishi, 2011, Nitric oxide, a Janus-faced therapeutic target for diabetic microangiopathy-friend or foe?, Pharmacol. Res., 64, 187, 10.1016/j.phrs.2011.05.009