Antidepressant-like activity and cardioprotective effects of fatty acid amide hydrolase inhibitor URB694 in socially stressed Wistar Kyoto rats

Albus, 2010, Psychological and social factors in coronary heart disease, Ann. Med., 42, 487, 10.3109/07853890.2010.515605 American Psychiatric Association, 2013 Báez-Mendoza, 2013, The role of the striatum in social behavior, Front. Neurosci., 7, 233, 10.3389/fnins.2013.00233 Becker, 2008, Repeated social defeat-induced depression-like behavioral and biological alterations in rats: involvement of cholecystokinin, Mol. Psychiatry, 13, 1079, 10.1038/sj.mp.4002097 Bisogno, 1999, Brain regional distribution of endocannabinoids: implications for their biosynthesis and biological function, Biochem. Biophys. Res. Commun., 256, 377, 10.1006/bbrc.1999.0254 Bonz, 2003, Cannabinoids acting on CB1 receptors decrease contractile performance in human atrial muscle, J. Cardiovasc. Pharmacol., 41, 657, 10.1097/00005344-200304000-00020 Bortolato, 2007, Antidepressant-like activity of the fatty acid amide hydrolase inhibitor URB597 in a rat model of chronic mild stress, Biol. Psychiatry, 62, 1103, 10.1016/j.biopsych.2006.12.001 Browne, 2015, Antidepressant-like effects of buprenorphine in rats are strain dependent, Behav. Brain. Res., 278, 385, 10.1016/j.bbr.2014.10.014 Calil, 2006, The comparison of immobility time in experimental rat swimming models, Life Sci., 79, 1712, 10.1016/j.lfs.2006.06.003 Carnevali, 2014, Low vagally-mediated heart rate variability and increased susceptibility to ventricular arrhythmias in rats bred for high anxiety, Physiol. Behav., 128, 16, 10.1016/j.physbeh.2014.01.033 Carnevali, 2013, Structural and electrical myocardial remodeling in a rodent model of depression, Psychosom. Med., 75, 42, 10.1097/PSY.0b013e318276cb0d Carney, 2005, Depression, the autonomic nervous system, and coronary heart disease, Psychosom. Med., 67, S29, 10.1097/01.psy.0000162254.61556.d5 Carroll, 2007, Pathophysiology of hypercortisolism in depression, Acta Psychiatr. Scand. Suppl., 90, 10.1111/j.1600-0447.2007.00967.x Clapper, 2009, A second generation of carbamate-based fatty acid amide hydrolase inhibitors with improved activity in vivo, ChemMedChem, 4, 1505, 10.1002/cmdc.200900210 Crowe, 2014, The endocannabinoid system modulates stress, emotionality, and inflammation, Brain Behav. Immun., 42, 1, 10.1016/j.bbi.2014.06.007 Cryan, 2005, Differential behavioral effects of the antidepressants reboxetine, fluoxetine, and moclobemide in a modified forced swim test following chronic treatment, Psychopharmacology (Berl), 182, 335, 10.1007/s00213-005-0093-5 Curtis, 2013, The Lambeth Conventions (II): guidelines for the study of animal and human ventricular and supraventricular arrhythmias, Pharmacol. Ther., 139, 213, 10.1016/j.pharmthera.2013.04.008 Fiorelli, 2013, Development of a multigram synthesis of URB937, a peripherally restricted FAAH inhibitor, Org. Process. Res. Dev., 17, 359, 10.1021/op300301u Gobbi, 2005, Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis, Proc. Natl. Acad. Sci. USA, 102, 18620, 10.1073/pnas.0509591102 Gorzalka, 2011, Putative role of endocannabinoid signaling in the etiology of depression and actions of antidepressants, Prog. Neuropsychopharmacol. Biol. Psychiatry, 35, 1575, 10.1016/j.pnpbp.2010.11.021 Grippo, 2011, 24-hour autonomic dysfunction and depressive behaviors in an animal model of social isolation: implications for the study of depression and cardiovascular disease, Psychosom. Med., 73, 59, 10.1097/PSY.0b013e31820019e4 Hiley, 2009, Endocannabinoids and the heart, J. Cardiovasc. Pharmacol., 53, 267, 10.1097/FJC.0b013e318192671d Hill, 2011, Recruitment of prefrontal cortical endocannabinoid signaling by glucocorticoids contributes to termination of the stress response, J. Neurosci., 31, 10506, 10.1523/JNEUROSCI.0496-11.2011 Jordan, 1995, Disorders of sinus function, 245 Kemp, 2014, Effects of depression, anxiety, comorbidity, and antidepressants on resting-state heart rate and its variability: an ELSA-Brasil cohort baseline study, Am. J. Psychiatry, 171, 1328, 10.1176/appi.ajp.2014.13121605 Kemp, 2012, Depression, comorbid anxiety disorders, and heart rate variability in physically healthy, unmedicated patients: implications for cardiovascular risk, PLoS One, 7, e30777, 10.1371/journal.pone.0030777 Klengel, 2013, Gene-environment interactions in major depressive disorder, Can. J. Psychiatry, 58, 76, 10.1177/070674371305800203 Krylatov, 2001, Activation of type II cannabinoid receptors improves myocardial tolerance to arrhythmogenic effects of coronary occlusion and reperfusion, Bull. Exp. Biol. Med., 131, 523, 10.1023/A:1012381914518 Lepicier, 2003, Endocannabinoids protect the rat isolated heart against ischaemia, Br. J. Pharmacol., 139, 805, 10.1038/sj.bjp.0705313 Liang, 2014, Reactive heart rate variability in male patients with first-episode major depressive disorder, Prog. Neuropsychopharmacol. Biol. Psychiatry, 56C, 52 Licht, 2010, Longitudinal evidence for unfavorable effects of antidepressants on heart rate variability, Biol. Psychiatry, 68, 861, 10.1016/j.biopsych.2010.06.032 Lo Verme, 2005, The nuclear receptor peroxisome proliferator-activated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide, Mol. Pharmacol., 67, 15, 10.1124/mol.104.006353 McKinney, 2005, Structure and function of fatty acid amide hydrolase, Annu. Rev. Biochem., 74, 411, 10.1146/annurev.biochem.74.082803.133450 Malkesman, 2008, A cross-fostering study in a genetic animal model of depression: maternal behavior and depression-like symptoms, Pharmacol. Biochem. Behav., 91, 1, 10.1016/j.pbb.2008.06.004 McLaughlin, 2014, A critical role for prefrontocortical endocannabinoid signaling in the regulation of stress and emotional behavior, Neurosci. Biobehav. Rev., 42, 116, 10.1016/j.neubiorev.2014.02.006 Moldrich, 2000, Localization of the CB1 cannabinoid receptor in the rat brain. an immunohistochemical study, Peptides, 21, 1735, 10.1016/S0196-9781(00)00324-7 Nam, 2014, Learned helplessness and social avoidance in the Wistar-Kyoto rat. Front, Behav. Neurosci., 8, 109 Niederhoffer, 1999, Involvement of CB1 cannabinoid receptors in the EDHF-dependent vasorelaxation in rabbits, Br. J. Pharmacol., 126, 1383, 10.1038/sj.bjp.0702452 O’Mahony, 2011, Strain differences in the neurochemical response to chronic restraint stress in the rat: relevance to depression, Pharmacol. Biochem. Behav., 97, 690, 10.1016/j.pbb.2010.11.012 O’Malley, 2010, Distinct alterations in colonic morphology and physiology in two rat models of enhanced stress-induced anxiety and depression-like behaviour, Stress, 13, 114, 10.3109/10253890903067418 Paxinos, 1986 Paré, 1993, Depressive behavior and stress ulcer in Wistar Kyoto rats, J. Physiol. Paris, 87, 229, 10.1016/0928-4257(93)90010-Q Plenis, 2011, Simultaneous determination of urinary cortisol, cortisone and corticosterone in parachutists, depressed patients and healthy controls in view of biomedical and pharmacokinetic studies, Mol. Biosyst., 7, 1487, 10.1039/c0mb00313a Porsolt, 1977, Depression: a new animal model sensitive to antidepressant treatments, Nature, 266, 730, 10.1038/266730a0 Rademacher, 2008, Effects of acute and repeated restraint stress on endocannabinoid content in the amygdala, ventral striatum, and medial prefrontal cortex in mice, Neuropharmacology, 54, 108, 10.1016/j.neuropharm.2007.06.012 Ramaekers, 2002, Cardiovascular autonomic function in conscious rats: a novel approach to facilitate stationary conditions, Ann. Noninvasive Electrocardiol., 7, 307, 10.1111/j.1542-474X.2002.tb00179.x Rea, 2014, Impaired endocannabinoid signalling in the rostral ventromedial medulla underpins genotype-dependent hyper-responsivity to noxious stimuli, Pain, 155, 69, 10.1016/j.pain.2013.09.012 Reich, 2009, Differential effects of chronic unpredictable stress on hippocampal CB1 receptors in male and female rats, Behav. Brain. Res., 203, 264, 10.1016/j.bbr.2009.05.013 Reyes Del Paso, 2013, The utility of low frequency heart rate variability as an index of sympathetic cardiac tone: a review with emphasis on a reanalysis of previous studies, Psychophysiology, 50, 477, 10.1111/psyp.12027 Riebe, 2011, Endocannabinoids and stress, Stress, 14, 384, 10.3109/10253890.2011.586753 Sgoifo, 2014, The socially stressed heart. Insights from studies in rodents, Neurosci. Biobehav. Rev., 39, 51, 10.1016/j.neubiorev.2013.12.005 Sgoifo, 1999, Different sympathovagal modulation of heart rate during social and nonsocial stress episodes in wild-type rats, Physiol. Behav., 67, 733, 10.1016/S0031-9384(99)00134-1 Surawicz, 2008 Tarzia, 2006, Synthesis and structure-activity relationships of FAAH inhibitors: cyclohexylcarbamic acid biphenyl esters with chemical modulation at the proximal phenyl ring, ChemMedChem, 1, 130, 10.1002/cmdc.200500017 Udupa, 2007, Alteration of cardiac autonomic functions in patients with major depression: a study using heart rate variability measures, J. Affect. Disord., 100, 137, 10.1016/j.jad.2006.10.007 Ugdyzhekova, 2001, Endogenous cannabinoid anandamide increases heart resistance to arrhythmogenic effects of epinephrine: role of CB(1) and CB(2) receptors, Bull. Exp. Biol. Med., 131, 251, 10.1023/A:1017651432193 Underdown, 2005, Anandamide reduces infarct size in rat isolated hearts subjected to ischaemia-reperfusion by a novel cannabinoid mechanism, Br. J. Pharmacol., 146, 809, 10.1038/sj.bjp.0706391 Vacondio, 2011, Biphenyl-3-yl alkylcarbamates as fatty acid amide hydrolase (FAAH) inhibitors: steric effects of N-alkyl chain on rat plasma and liver stability, Eur. J. Med. Chem., 46, 4466, 10.1016/j.ejmech.2011.07.021 Van der Kooy, 2007, Depression and the risk for cardiovascular diseases: systematic review and meta analysis, Int. J. Geriatr. Psychiatry, 22, 613, 10.1002/gps.1723 Vertes, 2006, Interactions among the medial prefrontal cortex, hippocampus and midline thalamus in emotional and cognitive processing in the rat, Neuroscience, 142, 1, 10.1016/j.neuroscience.2006.06.027 Vinod, 2012, Dysfunction in fatty acid amide hydrolase is associated with depressive-like behavior in Wistar Kyoto rats, PLoS One, 7, e36743, 10.1371/journal.pone.0036743 Wood, 2012, Depressive and cardiovascular disease comorbidity in a rat model of social stress: a putative role for corticotropin-releasing factor, Psychopharmacology (Berl), 222, 325, 10.1007/s00213-012-2648-6