Anticoagulation strategies and risk of bleeding events in critically ill COVID-19 patients

Medicina Intensiva - Tập 47 - Trang 1-8 - 2023
C. Gabara1, B. Solarat2, P. Castro1,3, S. Fernández1,3, J.R. Badia2, D. Toapanta4, S. Schulman5,6, J.C. Reverter7, A. Soriano8, J. Moisés2, J. Aibar1
1Internal Medicine Department, Hospital Clínic, IDIBAPS – University of Barcelona, Spain
2Pneumology Department, Hospital Clínic, IDIBAPS – University of Barcelona, Spain
3Medical Intensive Care Unit, Hospital Clínic, IDIBAPS – University of Barcelona, Spain
4Liver ICU, Hospital Clínic, IDIBAPS – University of Barcelona, Spain
5Department of Medicine, Thrombosis and Atherosclerosis Research Institute, McMaster University, Hamilton, Ontario, Canada
6Department of Obstetrics and Gynecology, I.M. Sechenov First Moscow State Medical University, Moscow, Russia
7Hematology Department, Hospital Clínic, IDIBAPS – University of Barcelona, Spain
8Infectious Disease Department, Hospital Clínic, IDIBAPS – University of Barcelona, Spain

Tài liệu tham khảo

Fogarty, 2020, COVID19 coagulopathy in Caucasian patients, Br J Haematol, 189, 1044, 10.1111/bjh.16749 Klok, 2020, Incidence of thrombotic complications in critically ill ICU patients with COVID-19, Thromb Res, 191, 145, 10.1016/j.thromres.2020.04.013 Wang, 2020, Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China, J Am Med Assoc, 323, 1061, 10.1001/jama.2020.1585 Tang, 2020, Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy, J Thromb Haemost, 18, 1094, 10.1111/jth.14817 Al-Samkari, 2020, COVID-19 and coagulation: bleeding and thrombotic manifestations of SARS-CoV-2 infection, Blood, 136, 489, 10.1182/blood.2020006520 Llitjos, 2020, High incidence of venous thromboembolic events in anticoagulated severe COVID-19 patients, J Thromb Haemost, 18, 1743, 10.1111/jth.14869 Paranjpe, 2020, Association of treatment dose anticoagulation with in-hospital survival among hospitalized patients with COVID-19, J Am Coll Cardiol, 76, 122, 10.1016/j.jacc.2020.05.001 Jonmarker, 2020, Dosing of thromboprophylaxis and mortality in critically ill COVID-19 patients, Crit Care, 24, 653, 10.1186/s13054-020-03375-7 Song, 2020, Chinese expert consensus on diagnosis and treatment of coagulation dysfunction in COVID-19, Mil Med Res, 7, 19 SETH. Recomendaciones de tromboprofilaxis y tratamiento antitrombótico en pacientes. Soc Española Trombos y Hemost 2020. Thachil, 2020, ISTH interim guidance on recognition and management of coagulopathy in COVID-19, J Thromb Haemost, 18, 1023, 10.1111/jth.14810 Cattaneo, 2020, Pulmonary embolism or pulmonary thrombosis in COVID-19? Is the recommendation to use high-dose heparin for thromboprophylaxis justified?, Thromb Haemost, 120, 1230, 10.1055/s-0040-1712097 Ackermann, 2020, Pulmonary vascular endothelialitis thrombosis, and angiogenesis in Covid-19, N Engl J Med, 383, 120, 10.1056/NEJMoa2015432 Arnold, 2007, Bleeding during critical illness: a prospective cohort study using a new measurement tool, Clin Investig Med, 30, 93, 10.25011/cim.v30i2.985 Schulman, 2010, Definition of major bleeding in clinical investigations of antihemostatic medicinal products in surgical patients, J Thromb Haemost, 8, 202, 10.1111/j.1538-7836.2009.03678.x Douma, 2010, Potential of an age adjusted D-dimer cut-off value to improve the exclusion of pulmonary embolism in older patients: a retrospective analysis of three large cohorts, BMJ, 340, 1475c, 10.1136/bmj.c1475 Jiménez, 2021, Incidence of VTE and bleeding among hospitalized patients with COVID-19: a systematic review and meta-analysis, Chest, 159, 1196 Bikdeli, 2021, Intermediate-dose versus standard-dose prophylactic anticoagulation in patients with COVID-19 admitted to the intensive care unit: 90-day results from the INSPIRATION randomized trial, Thromb Haemost Mattioli, 2020, Safety of intermediate dose of low molecular weight heparin in COVID-19 patients, J Thromb Thrombolysis, 13, 1 Kessler, 2020, Bleeding prevalence in COVID-19 patients receiving intensive antithrombotic prophylaxis, J Thromb Thrombolysis, 50, 5, 10.1007/s11239-020-02244-y Pesavento, 2020, The hazard of (sub)therapeutic doses of anticoagulants in non-critically ill patients with Covid-19: the Padua province experience, J Thromb Haemost, 18, 2629, 10.1111/jth.15022