Antibiotics Concentrations in a Patient with Postoperative Endophthalmitis
Tóm tắt
We report a case of endophthalmitis who underwent a vitreous biopsy to assess sensitivity and to inject broad-spectrum intraocular antibiotics. Minimal inhibitory concentration (MIC) values of antibiotics against a coagulase-negative staphylococcus and Proprionibacterium acnes were also assessed.
Tài liệu tham khảo
Norregaard JC, Thoning H, Bernth-Petersen P, et al. Risk of endophthalmitis after cataract extraction: results from the International Cataract Surgery Outcomes Study. Br J Ophthalmol 1997;81:102–106.
Okhravi N, Towler HM, Hykin P, et al. Assessment of a standard treatment protocol on visual outcome following presumed bacterial endophthalmitis. Br J Ophthalmol 1997;81:719–725.
Endophthalmitis Vitrectomy Study Group. Results of the Endophthalmitis Vitrectomy Study. A randomized trial of immediate vitrectomy and of intravenous antibiotics for the treatment of postoperative bacterial endophthalmitis. Arch Ophthalmol 1995;113:1479–1496.
Gan IM, van Dissel JT, Beekhuis WH, et al. Intravitreal vancomycin and gentamicin concentrations in patients with postoperative endophthalmitis. Br J Ophthalmol 2001;85:1289–1293.
Ferencz FR, Assia EI, Diamantstein L, et al. Vancomycin concentration in the vitreous after intravenous and intravitreal administration for postoperative endophthalmitis. Arch Ophthalmol 1999;117:1023–1027.
Whitcher JP. The treatment of endophthalmitis-still an exercise in frustration. Br J Ophthalmol 1997;81:713–714.
Rogers NK, Fox PD, Noble BA, et al. Aggressive management of an epidemic of chronic pseudophakic endophthalmitis: results and literature survey. Br J Ophthalmol 1994;78:115–119.
Gurler B, Ozkul Y, Bitiren M, et al. A study on the toxicity of intravitreal levofloxacin in rabbits. Curr Eye Res 2002;24:253–262.
Herbert EN, Pearce IA, McGalliard J, Wong D, Groenewald C. Vitreous penetration of levofloxacin in the uninflamed phakic human eye. Br J Ophthalmol 2002;86:387–389.