Anti-infective potential of natural products: How to develop a stronger in vitro ‘proof-of-concept’

Journal of Ethnopharmacology - Tập 106 Số 3 - Trang 290-302 - 2006
Paul Cos1, Arnold J. Vlietinck2, Dirk Vanden Berghe1, Louis Maes3,1
1Laboratory for Microbiology, Parasitology and Hygiene (LMPH), Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Universiteitsplein 1, 2610, Antwerp, Belgium
2Laboratory of Pharmacognosy and Phytochemistry, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium
3Institute of Tropical Medicine, Nationalestraat 155, B-2000 Antwerp, Belgium

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Anon., 2000, Determination of minimum inhibitory concentrations (MICs) of antibacterial agents by agar dilution, Clinical Microbiology and Infection, 6, 509, 10.1046/j.1469-0691.2000.00142.x

Anon., 2003, Determination of minimum inhibitory concentrations (MICs) of antibacterial agents by broth dilution, Clinical Microbiology and Infection, 9, 1

Buckner, 1996, Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing beta-galactosidase, Antimicrobial Agents and Chemotherapy, 40, 2592, 10.1128/AAC.40.11.2592

Butaye, 2000, Influence of different medium components on the in vitro activity of the growth-promoting antibiotic flavomycin against enterococci, Journal of Antimicrobial Chemotherapy, 46, 713, 10.1093/jac/46.5.713

Chand, 1994, Rapid screening of the antimicrobial activity of extracts and natural products, Journal of Antibiotics, 47, 1295, 10.7164/antibiotics.47.1295

Clardy, 2004, Lessons from natural molecules, Nature, 432, 829, 10.1038/nature03194

Clarke, 2001, Potential problems with fluorescein diacetate assays of cell viability when testing natural products for antimicrobial activity, Journal of Microbiological Methods, 46, 261, 10.1016/S0167-7012(01)00285-8

Cole, 1994, Key antifungal, antibacterial and anti-insect assays—a critical review, Biochemical Systematics and Ecology, 22, 837, 10.1016/0305-1978(94)90089-2

Corbett, 2004, A novel DNA-based microfluorimetric method to evaluate antimalarial drug activity, American Journal of Tropical Medicine and Hygiene, 70, 119, 10.4269/ajtmh.2004.70.119

Cordell, 2005, Some thoughts on the future of ethnopharmacology, Journal of Ethnopharmacology, 100, 5, 10.1016/j.jep.2005.05.027

Cordell, 1993, Separation, structure elucidation, and bioassay of cytotoxic natural products, 195

Debrabant, 2004, Generation of Leishmania donovani axenic amastigotes: their growth and biological characteristics, International Journal of Parasitology, 34, 205, 10.1016/j.ijpara.2003.10.011

Desjardins, 1979, Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique, Antimicrobial Agents and Chemotherapy, 16, 710, 10.1128/AAC.16.6.710

Eloff, 1998, A sensitive and quick microplate method to determine the minimal inhibitory concentration of plant extracts for bacteria, Planta Medica, 64, 711, 10.1055/s-2006-957563

Fabricant, 2001, The value of plants used in traditional medicine for drug discovery, Environmental Health Perspectives, 109, 69, 10.1289/ehp.01109s169

Gabrielson, 2002, Evaluation of redox indicators and the use of digital scanners and spectrophotometer for quantification of microbial growth in microplates, Journal of Microbiological Methods, 50, 63, 10.1016/S0167-7012(02)00011-8

Hadacek, 2000, Testing of antifungal natural products: methodologies, comparability of results and assay choice, Phytochemical Analysis, 11, 137, 10.1002/(SICI)1099-1565(200005/06)11:3<137::AID-PCA514>3.0.CO;2-I

Hamburger, 1987, A direct bioautographic TLC assay for compounds possessing antibacterial activity, Journal of Natural Products, 50, 19, 10.1021/np50049a003

Hart, 2005, Finding the target after screening the phenotype, Drug Discovery Today, 10, 513, 10.1016/S1359-6446(05)03415-X

Hirumi, 1989, Continuous cultivation of Trypanosoma brucei blood stream forms in a medium containing a low concentration of serum protein without feeder cell layers, Journal of Parasitology, 75, 985, 10.2307/3282883

Ieven, 1979, Screening of higher plants for biological activities I. Antimicrobial activity, Planta Medica, 36, 311, 10.1055/s-0028-1097277

Jahn, 1995, Susceptibility testing of Candida albicans and Aspergillus species by a simple microtitre menadione-augmented 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide assay, Journal of Clinical Microbiology, 33, 661, 10.1128/JCM.33.3.661-667.1995

Kitchen, 2004, Docking and scoring in virtual screening for drug discovery: methods and applications, Nature Reviews Drug Discovery, 3, 935, 10.1038/nrd1549

Maes, 2004, In vitro and in vivo activities of a triterpenoid saponin extract (PX-6518) from the plant Maesa balansae against visceral Leishmania species, Antimicrobial Agents and Chemotherapy, 48, 130, 10.1128/AAC.48.1.130-136.2004

Mah, 2001, Mechanisms of biofilm resistance to antimicrobial agents, Trends in Microbiology, 9, 34, 10.1016/S0966-842X(00)01913-2

Makler, 1993, Parasite lactate dehydrogenase as an assay for Plasmodium falciparum drug sensitivity, American Journal of Tropical Medicine and Hygiene, 48, 739, 10.4269/ajtmh.1993.48.739

McMillian, 2002, An improved resazurin-based cytotoxicity assay for hepatic cells, Cell Biology and Toxicology, 18, 157, 10.1023/A:1015559603643

Mitscher, 1972, Antimicrobial agents from higher plants—1. Introduction, rationale, and methodology, Lloydia, 35, 157

Okeke, 2005, Antimicrobial resistance in developing countries. Part 1: recent trends and current status, Lancet Infectious Diseases, 5, 481, 10.1016/S1473-3099(05)70189-4

Patwardhan, 2005, Ethnopharmacology and drug discovery, Journal of Ethnopharmacology, 100, 50, 10.1016/j.jep.2005.06.006

Pelloux-Prayer, 1998, Kinetic evaluation of conidial germination of Botrytis cinerea by a spectrofluorometric method, Mycology Research, 102, 320, 10.1017/S095375629700511X

Pink, 2005, Opportunities and challenges in antiparasitic drug discovery, Nature Reviews Drug Discovery, 4, 727, 10.1038/nrd1824

Rahalison, 1991, A bioautographic agar overlay method for the detection of antifungal compounds from higher plants, Phytochemical Analysis, 2, 199, 10.1002/pca.2800020503

Raz, 1997, The Alamar Blue assay to determine drug sensitivity of African trypanosomes (T.b. rhodensiense and T.b. gambiense) in vitro, Acta Tropica, 68, 139, 10.1016/S0001-706X(97)00079-X

Remme, 2002, Strategic emphases for tropical diseases research: a TDR perspective, Trends in Microbiology, 10, 435, 10.1016/S0966-842X(02)02431-9

Rios, 2005, Medicinal plants and antimicrobial activity, Journal of Ethnopharmacology, 100, 80, 10.1016/j.jep.2005.04.025

Rios, 1988, Screening methods for natural products with antimicrobial activity: a review of the literature, Journal of Ethnopharmacology, 23, 127, 10.1016/0378-8741(88)90001-3

Sams-Dodd, 2005, Target-based drug discovery: is something wrong?, Drug Discovery Today: Targets, 10, 139, 10.1016/S1359-6446(04)03316-1

Sawai, 2002, Indirect conductimetric assay of antibacterial activities, Journal of Industrial Microbiology & Technology, 29, 296, 10.1038/sj.jim.7000314

Trager, 1976, Human malaria parasites in continuous culture, Science, 193, 673, 10.1126/science.781840

Vanden Berghe, 1991, Screening for antibacterial and antiviral agents, 47

Verkman, 2004, Drug discovery in academia, American Journal of Physiology—Cell Physiology, 286, 465, 10.1152/ajpcell.00397.2003

Verpoorte, 2005, Ethnopharmacology and systems biology: a perfect holistic match, Journal of Ethnopharmacology, 100, 53, 10.1016/j.jep.2005.05.033

Vlietinck, 1991, Can ethnopharmacology contribute to the development of antiviral drugs?, Journal of Ethnopharmacology, 32, 141, 10.1016/0378-8741(91)90112-Q

Zak, 1999