Anti-high-mobility group box-1 treatment strategies improve trauma-induced coagulopathy in a mouse model of trauma and shock

British Journal of Anaesthesia - Tập 130 - Trang 687-697 - 2023
Pieter H. Sloos1,2, M. Adrie W. Maas2, Joost C.M. Meijers3,4,5, Rienk Nieuwland6,7, Joris J.T.H. Roelofs8, Nicole P. Juffermans1,2,9, Derek J.B. Kleinveld1,2,10
1Amsterdam UMC Location University of Amsterdam, Department of Intensive Care Medicine, Amsterdam, the Netherlands
2Amsterdam UMC Location University of Amsterdam, Laboratory of Experimental Intensive Care and Anesthesiology, Amsterdam, the Netherlands
3Amsterdam UMC Location University of Amsterdam, Department of Experimental Vascular Medicine, Amsterdam, the Netherlands
4Amsterdam Cardiovascular Sciences, Pulmonary Hypertension and Thrombosis, Amsterdam, The Netherlands
5Sanquin Research, Department of Molecular Hematology, Amsterdam, the Netherlands
6Amsterdam UMC Location University of Amsterdam, Laboratory of Experimental Clinical Chemistry, Amsterdam, the Netherlands
7Amsterdam UMC Location University of Amsterdam, Vesicle Observation Center, Amsterdam, the Netherlands
8Amsterdam UMC Location University of Amsterdam, Department of Pathology, Amsterdam, the Netherlands
9Onze Lieve Vrouwe Gasthuis, Department of Intensive Care Medicine, Amsterdam, the Netherlands
10Erasmus MC, Department of Anesthesiology, Rotterdam, the Netherlands

Tài liệu tham khảo

2018, Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017, Lancet, 392, 1736, 10.1016/S0140-6736(18)32203-7 Oyeniyi, 2017, Trends in 1029 trauma deaths at a level 1 trauma center: impact of a bleeding control bundle of care, Injury, 48, 5, 10.1016/j.injury.2016.10.037 Koh, 2019, Trends in potentially preventable trauma deaths between 2005–2006 and 2012–2013, Am J Surg, 218, 501, 10.1016/j.amjsurg.2018.12.022 Brohi, 2003, Acute traumatic coagulopathy, J Trauma, 54, 1127 Kutcher, 2012, Characterization of platelet dysfunction after trauma, J Trauma Acute Care Surg, 73, 13, 10.1097/TA.0b013e318256deab Sloos, 2022, Platelet dysfunction after trauma: from mechanisms to targeted treatment, Transfusion, 62, S281, 10.1111/trf.16971 St John, 2019, Platelets retain inducible alpha granule secretion by P-selectin expression but exhibit mechanical dysfunction during trauma-induced coagulopathy, J Thromb Haemost, 17, 771, 10.1111/jth.14414 Vulliamy, 2019, Histone H4 induces platelet ballooning and microparticle release during trauma hemorrhage, Proc Natl Acad Sci U S A, 116, 17444, 10.1073/pnas.1904978116 Vulliamy, 2020, Loss of GPVI and GPIbα contributes to trauma-induced platelet dysfunction in severely injured patients, Blood Adv, 4, 2623, 10.1182/bloodadvances.2020001776 Ramsey, 2016, A prospective study of platelet function in trauma patients, J Trauma Acute Care Surg, 80, 726, 10.1097/TA.0000000000001017 Wohlauer, 2012, Early platelet dysfunction: an unrecognized role in the acute coagulopathy of trauma, J Am Coll Surg, 214, 739, 10.1016/j.jamcollsurg.2012.01.050 Peltz, 2009, HMGB1 is markedly elevated within 6 hours of mechanical trauma in humans, Shock, 32, 17, 10.1097/SHK.0b013e3181997173 Vogel, 2015, Platelet-derived HMGB1 is a critical mediator of thrombosis, J Clin Invest, 125, 4638, 10.1172/JCI81660 Cohen, 2009, Early release of high mobility group box nuclear protein 1 after severe trauma in humans: role of injury severity and tissue hypoperfusion, Crit Care, 13, R174, 10.1186/cc8152 Vogel, 2016, Platelet-derived high-mobility group box 1 promotes recruitment and suppresses apoptosis of monocytes, Biochem Biophys Res Commun, 478, 143, 10.1016/j.bbrc.2016.07.078 Ito, 2007, High-mobility group box 1 protein promotes development of microvascular thrombosis in rats, J Thromb Haemost, 5, 109, 10.1111/j.1538-7836.2006.02255.x Abeyama, 2005, The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism, J Clin Invest, 115, 1267, 10.1172/JCI22782 Ito, 2008, Proteolytic cleavage of high mobility group box 1 protein by thrombin-thrombomodulin complexes, Arterioscler Thromb Vasc Biol, 28, 1825, 10.1161/ATVBAHA.107.150631 Zhou, 2009, Generation of monoclonal antibodies against highly conserved antigens, PLoS One, 4, 10.1371/journal.pone.0006087 Yang, 2022, HMGB1 inhibition to ameliorate organ failure and increase survival in trauma, Biomolecules, 12, 101, 10.3390/biom12010101 Percie du Sert, 2020, The ARRIVE guidelines 2.0: updated guidelines for reporting animal research, PLoS Biol, 18 Liu, 2012, Standardizing a simpler, more sensitive and accurate tail bleeding assay in mice, World J Exp Med, 2, 30, 10.5493/wjem.v2.i2.30 Bonnard, 2017, Development and validation of a high throughput whole blood thrombolysis plate assay, Sci Rep, 7, 2346, 10.1038/s41598-017-02498-2 Mosnier, 2001, Regulation of fibrinolysis in plasma by TAFI and protein C is dependent on the concentration of thrombomodulin, Thromb Haemost, 85, 5, 10.1055/s-0037-1612655 Giannoudis, 2010, Pattern of release and relationship between HMGB-1 and IL-6 following blunt trauma, Injury, 41, 1323, 10.1016/j.injury.2010.09.012 Polito, 2016, Prognostic value of HMGB1 and oxidative stress markers in multiple trauma patients: a single-centre prospective study, Int J Immunopathol Pharmacol, 29, 504, 10.1177/0394632016656187 Yang, 2015, HMGB1: a novel protein that induced platelets active and aggregation via Toll-like receptor-4, NF-κB and cGMP dependent mechanisms, Diagn Pathol, 10, 134, 10.1186/s13000-015-0348-3 Hamada, 2022, Impact of platelet transfusion on outcomes in trauma patients, Crit Care, 26, 49, 10.1186/s13054-022-03928-y Watanabe-Kusunoki, 2020, Thrombomodulin as a physiological modulator of intravascular injury, Front Immunol, 11, 10.3389/fimmu.2020.575890 Brohi, 2008, Acute coagulopathy of trauma: hypoperfusion induces systemic anticoagulation and hyperfibrinolysis, J Trauma, 64, 1211 van Moorsel, 2022, VhH anti-thrombomodulin clone 1 inhibits TAFI activation and enhances fibrinolysis in human whole blood under flow, J Thromb Haemost, 20, 1213, 10.1111/jth.15674 Raife, 2011, Human thrombomodulin knock-in mice reveal differential effects of human thrombomodulin on thrombosis and atherosclerosis, Arterioscler Thromb Vasc Biol, 31, 2509, 10.1161/ATVBAHA.111.236828 Ahrens, 2015, HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi, Thromb Haemost, 114, 994, 10.1160/TH14-12-1073 Tang, 2013, Time course of soluble P-selectin and von Willebrand factor levels in trauma patients: a prospective observational study, Scand J Trauma Resusc Emerg Med, 21, 70, 10.1186/1757-7241-21-70 Panicker, 2017, Circulating soluble P-selectin must dimerize to promote inflammation and coagulation in mice, Blood, 130, 181, 10.1182/blood-2017-02-770479 Dyer, 2018, Deep vein thrombosis in mice is regulated by platelet HMGB1 through release of neutrophil-extracellular traps and DNA, Sci Rep, 8, 2068, 10.1038/s41598-018-20479-x Sloos, 2022, The effect of shock duration on trauma-induced coagulopathy in a murine model, Intensive Care Med Exp, 10, 1, 10.1186/s40635-021-00428-1