Anti-breast cancer potential of a new xanthine derivative: In silico, antiproliferative, selectivity, VEGFR-2 inhibition, apoptosis induction and migration inhibition studies

Pathology - Research and Practice - Tập 251 - Trang 154894 - 2023
Ibrahim H. Eissa1, Reda G. Yousef1, Hazem Elkady1, Eslam B. Elkaeed2, Bshra A. Alsfouk3, Dalal Z. Husein4, Mostafa A. Asmaey5, Ibrahim M. Ibrahim6, Ahmed M. Metwaly7,8
1Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo 11884, Egypt
2Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh 13713, Saudi Arabia
3Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia
4Chemistry Department, Faculty of Science, New Valley University, El-Kharja 72511, Egypt
5Department of Chemistry, Faculty of Science, Al-Azhar University, Assiut Branch, 71524 Assiut, Egypt
6Biophysics Department, Faculty of Science, Cairo University. Cairo 12613, Egypt
7Pharmacognosy and Medicinal Plants Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo 11884, Egypt
8Biopharmaceutical Products Research Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), Alexandria, Egypt

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