Anti-angiopoietin therapy with trebananib for recurrent ovarian cancer (TRINOVA-1): a randomised, multicentre, double-blind, placebo-controlled phase 3 trial

The Lancet Oncology - Tập 15 Số 8 - Trang 799-808 - 2014
Bradley J. Monk1, Andrés Poveda2, Ignace Vergote3, Francesco Raspagliesi4, Keiichi Fujiwara5, Duk‐Soo Bae6, Ana Oaknin7, Isabelle Ray‐Coquard8, Diane Provencher9, Beth Y. Karlan10, Catherine Lhommé11, Gary Richardson12, Dolores Gallardo Rincón13, Robert L. Coleman14, Thomas J. Herzog15, Christian Marth16, Arija Brize17, Michel Fabbro18, Andrés Redondo19, Aristotelis Bamias20, Marjan Tassoudji21, Lynn Navale22, Douglas Warner22, Amit M. Oza23
1Creighton University School of Medicine and University of Arizona Cancer Center at St. Joseph's Hospital, Phoenix, AZ, USA
2Fundacion Instituto Valenciano de Oncología, Valencia, Spain
3University Hospital Leuven, KU Leuven, Leuven, Belgium
4Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
5Saitama Medical University International Medical Center, Hidaka-Shi, Japan
6Samsung Medical Center, Seoul, South Korea
7Vall d'Hebron Institute of Oncology, Barcelona, Spain
8Université Lyon-I, Centre Léon Bérard, Lyon, France
9Centre hospitalier de l’Université de Montréal, Montreal, QC, Canada
10Cedars-Sinai Medical Center, Los Angeles, CA, USA
11Gustave Roussy, Villejuif, France
12Cabrini Hospital, Malvern, Vic, Australia
13Instituto Nacional de Cancerologia, Mexico City, Mexico
14University of Texas/MD Anderson Cancer Center, Houston, TX USA
15Columbia University Medical Center, New York, NY, USA;
16Medical University Innsbruck, Innsbruck, Austria
17Riga Eastern Clinical University Hospital, Riga, Latvia
18Regional Cancer Institute Montpellier, Montpellier, France
19University Hospital La Paz, Madrid, Spain
20Alexandra Hospital, Department of Clinical Therapeutics, National & Kapodistrian University of Athens, Athens, Greece
21Amgen, Uxbridge, UK
22Amgen, Thousand Oaks, CA, USA
23Princess Margaret Cancer Centre, Toronto, ON, Canada

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