Nội dung được dịch bởi AI, chỉ mang tính chất tham khảo
Chán ăn
Tóm tắt
Ở những bệnh nhân mắc ung thư giai đoạn muộn, chán ăn hoặc mất cảm giác thèm ăn rất phổ biến, gây distress và dự đoán tiên lượng kém. Những bệnh nhân ung thư đang điều trị liệu pháp chống ung thư thường gặp phải triệu chứng này, cũng như những bệnh nhân ung thư không còn nhận liệu pháp này nữa. Tuy nhiên, các tùy chọn điều trị giảm nhẹ còn hạn chế. Hai biện pháp điều trị giảm nhẹ thường được sử dụng nhất là sử dụng các tác nhân progestational và corticosteroid. Cả hai loại tác nhân này chỉ mang lại lợi ích lâm sàng khiêm tốn. Các nghiên cứu gần đây cho thấy kết quả đầy hứa hẹn với melatonin, chặn yếu tố hoại tử khối u-α, chất đánh lừa yếu tố hoại tử-κ B, adenosine triphosphate, thuốc chống nôn và các tác nhân chống viêm. Những tác nhân này có vẻ đầy hứa hẹn, nhưng cần nhiều nghiên cứu lâm sàng hơn trước khi chúng có thể được chỉ định bên ngoài các thử nghiệm lâm sàng.
Từ khóa
#ung thư #chán ăn #điều trị giảm nhẹ #progestational #corticosteroid #melatonin #yếu tố hoại tử khối u #thuốc chống nôn #tác nhân chống viêmTài liệu tham khảo
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