Animal models of Alzheimer's disease: experimental cholinergic denervation

Altman, 1985, Further characterizations of the nature of the behavioral and neurochemical effects of lesions to the nucleus basalis of Meynert in the rat, Neurobiol. Aging, 6, 125, 10.1016/0197-4580(85)90030-2 Arendt, 1985, Neuronal loss in different parts of the nucleus basalis is related to neuritic plaque formation in cortical target areas in Alzheimer's disease, Neuroscience, 14, 1, 10.1016/0306-4522(85)90160-5 Bailey, 1986, Effects of intrahippocampal injections of the cholinergic neurotoxin AF64A on open-field activity and avoidance learning in the rat, Behav. Neural Biol., 45, 263, 10.1016/S0163-1047(86)80015-2 Bammer, 1982, Pharmacological investigations of neurotransmitter involvement in passive avoidance responding: a review and some new results, Neurosci. Biobehav. Rev., 6, 247, 10.1016/0149-7634(82)90041-0 Ben-Barak, 1980, Scopolamine induces an increase in muscarinic receptor level in rat hippocampus, Brain Res., 193, 309, 10.1016/0006-8993(80)90973-7 Bennet-Clarke, 1986, Cortical projections from somatostatin neurons of the basal forebrain in the rat, Soc. Neurosci. Abstr., 12, 300 Bartus, 1978, Evidence for a direct cholinergic involvement in the scopolamine-induced amnesia in monkeys: effects of concurrent administration of physostigmine and methyphenidate with scopolamine, Pharmacol. Biochem. Behav., 9, 833, 10.1016/0091-3057(78)90364-7 Bartus, 1985, Selective memory loss following nucleus basalis lesions: long term behavioral recovery despite persistent cholinergic deficiencies, Pharmacol. Biochem. Behav., 23, 125, 10.1016/0091-3057(85)90139-X Beatty, 1986, Patterns of memory failure after scopolamine treatment: implications for cholinergic hypothesis of dementia, Behav. Neural Biol., 45, 196, 10.1016/S0163-1047(86)90772-7 Bird, 1975, Denervation supersensitivity in the cholinergic septohippocampal pathway: a microiontophoretic study, Brain Res., 100, 355, 10.1016/0006-8993(75)90488-6 Boegman, 1985, Quinolinic acid neurotoxicity in the nucleus basalis antagonized by kynurenic acid, Neurobiol. Aging, 6, 331, 10.1016/0197-4580(85)90012-0 Brandeis, 1986, AF64A induced cholinotoxicity: behavioral and biochemical correlates, 469 Buresova, 1986, Differential effects of cholinergic blockade on performance of rats in the water tank navigation task and in a radial arm maze, Behav. Neurosci., 100, 476, 10.1037/0735-7044.100.4.476 Butcher, 1978, Dopamine neurons in pars compacta of the substantia nigra contain acetylcholinesterase: histochemical correlations on the same brain section, Eur. J. Pharmacol., 52, 415, 10.1016/0014-2999(78)90301-1 Casamenti, 1985, Effects of ganglioside treatment in rats with a lesion of the cholinergic forebrain nuclei, Brain Res., 338, 45, 10.1016/0006-8993(85)90246-X Chui, 1984, Stability of neuronal number in the human nucleus basalis of Meynert with age, Neurobiol. Aging, 5, 83, 10.1016/0197-4580(84)90035-6 Coyle, 1985, Neuron-specific cytotoxins, Vol. 9, 299 Coyle, 1983, The use of excitatory amino acids as selective neurotoxins, Vol. 1, 508 Coyle, 1984, Neurotransmitter specific alterations in dementing disorders: insights from animal models, J. Psychiat. Res., 18, 501, 10.1016/0022-3956(84)90037-2 Cumin, 1982, Effects of the novel compound aniracetam (R013-5057) upon impaired learning and memory in rodents, Psychopharmacology, 78, 104, 10.1007/BF00432244 Davies, 1980, Reduced somatostatin-like immunoreactivity in cases of Alzheimer's disease and senile dementia of the Alzheimer type, Nature (Lond.), 288, 279, 10.1038/288279a0 Davies, 1976, Selective loss of central cholinergic neurons in Alzheimer's disease, Lancet, 2, 1403, 10.1016/S0140-6736(76)91936-X DeBelleroche, 1985, Analysis of muscarinic receptor concentration and sub-types following lesions of the rat substantia innominata, Brain Res., 340, 201, 10.1016/0006-8993(85)90915-1 Denoble, 1986, Vinpocetine: nootropic effects on scopolamine induced and hypoxia induced retrieval deficits of a step through passive avoidance response in rats, Pharmacol. Biochem. Behav., 24, 1123, 10.1016/0091-3057(86)90465-X Drachman, 1977, Memory and cognitive function in man: does the cholinergic system have a specific role?, Neurology, 27, 783, 10.1212/WNL.27.8.783 Drachman, 1974, Human memory and the cholinergic system, Arch. Neurol., 30, 113, 10.1001/archneur.1974.00490320001001 Dubois, 1985, Profound disturbances of spontaneous and learned behaviors following lesions of the nucleus basalis magnocellularis in the rat, Brain Res., 338, 249, 10.1016/0006-8993(85)90154-4 El-Defrawy, 1985, Functional and neurochemical cortical cholinergic impairment following neurotoxic lesions of the nucleus basalis magnocellularis in the rat, Neurobiol. Aging, 6, 325, 10.1016/0197-4580(85)90011-9 Ezrin-Waters, 1986, The nucleus basalis of Meynert, Can. J. Neural., 13, 8, 10.1017/S0317167100035721 Fine, 1985, Transplantation of embryonic ventral forebrain neurons to the neocortex of rats with lesions of the nucleus basalis magnocellularis. I. Biochemical and anatomical observations, Neuroscience, 16, 769, 10.1016/0306-4522(85)90093-4 Fisher, 1986, The AF64A treated rat as an experimental model for Alzheimer's disease: a critical evaluation, 427 Flicker, 1983, Behavioral and neurochemical effects following neurotoxic lesions of a major cholinergic input to the cerebral cortex, Pharmacol. Biochem. Behav., 18, 973, 10.1016/S0091-3057(83)80023-9 Flood, 1986, Scopolamine effects on memory retention in mice: a model of dementia?, Behav. Neural Biol., 45, 169, 10.1016/S0163-1047(86)90750-8 Friedland, 1983, Regional cerebral metabolic alterations in dementia of the Alzheimer type: positron emission tomography with [18F]fluorodeoxyglucose, J. Comp. Asst. Tomogr., 7, 590, 10.1097/00004728-198308000-00003 Friedman, 1983, Loss of cholinergic neurons in rat neocortex produces deficits in passive avoidance learning, Pharmacol. Biochem. Behav., 19, 309, 10.1016/0091-3057(83)90057-6 Fuld, 1984, Test profile of cholinergic dysfunction and of Alzheimer-type dementia, J. Clin. Neuropsychol., 6, 380, 10.1080/01688638408401229 Godding, 1982, Scopolamine does not disrupt spatial working memory in rats, Pharmacol. Biochem. Behav., 16, 919, 10.1016/0091-3057(82)90045-4 Haroutunian, 1985, Pharmacological alleviation of cholinergic lesion induced memory deficits in rats, Life Sci., 37, 945, 10.1016/0024-3205(85)90531-4 Hefti, 1984, Chronic intraventricular injections of nerve growth factor elevate hippocampal choline acetyltransferase activity in adult rats with partial septo-hippocampal lesions, Brain Res., 293, 305, 10.1016/0006-8993(84)91237-X Hepler, 1985, Lesions in nucleus basalis magnocellularis and medial septal area of rats produce qualitatively similar memory impairments, J. Neurosci., 5, 866, 10.1523/JNEUROSCI.05-04-00866.1985 Hiraga, 1984, Effects of cholinergic and monoaminergic antagonists and tranquilizers upon spatial memory in rats, Pharmacol. Biochem. Behav., 20, 205, 10.1016/0091-3057(84)90243-0 Hughey, 1986, Spontaneous, cholinergic-dependent, behavioral recovery following basal forebrain lesions in rats, Soc. Neurosci. Abstr., 12, 713 Jarrard, 1984, Behavioral and neurochemical effects of intraventricular administration of AF64A in rats, Pharmacol. Biochem. Behav., 21, 273, 10.1016/0091-3057(84)90226-0 Johnson, 1981, Laminar distribution of cholinergic markers in neocortex: effects of lesions, J. Neurosci. Res., 6, 597, 10.1002/jnr.490060506 Kasa, 1986, Histochemical and electron microscopic study of the brain of the AF64A treated rat, 447 Knowlton, 1985, Basal forebrain lesions produce a dissociation of trial-dependent and trial-independent memory performance, Brain Res., 345, 315, 10.1016/0006-8993(85)91008-X Kozlowski, 1986, Specific toxic effects of ethylcholine nitrogen mustard on cholinergic neurons of the nucleus basalis, Brain Res., 372, 45, 10.1016/0006-8993(86)91457-5 LaMarca, 1984, Deoxyglucose uptake and choline acetyltranferase activity in cerebral cortex following lesions of the nucleus basalis magnocellularis, Brain Res., 307, 366, 10.1016/0006-8993(84)90497-9 Lerer, 1986, A longitudinal examination of the behavioral and biochemical deficits produced by ibotenate lesions of the rat nucleus basalis magnocellularis, Soc. Neurosci. Abstr., 16, 553 Lerer, 1985, Cortical cholinergic impairment and behavioral deficits produced by kainic acid lesions of rat magnocellular basal forebrain, Behav. Neurosci., 99, 661, 10.1037/0735-7044.99.4.661 LoConte, 1982, Lesions of the cholinergic forebrain nuclei: changes in avoidance behavior and scopolamine actions, Pharmacol. Biochem. Behav., 17, 933, 10.1016/0091-3057(82)90475-0 London, 1984, Decreased cortical glucose utilization after ibotenate lesion of the rat ventromedial globus pallidus, J. Cereb. Blood Flow Metabol., 4, 381, 10.1038/jcbfm.1984.56 Loullis, 1983, Chronic administration of cholinergic agents: effects on behavior and calmodulin, Pharmacol. Biochem. Behav., 18, 601, 10.1016/0091-3057(83)90287-3 Mantione, 1984, Possible mechanisms involved in the presynaptic cholinotoxicity due to ethylcholine aziridinium (AF64A) in vivo, Life Sci., 35, 33, 10.1016/0024-3205(84)90149-8 Mantione, 1983, Selective presynaptic cholinergic neurotoxicity following intrahippocampal AF64A injection in rats, J. Neurochem., 41, 251, 10.1111/j.1471-4159.1983.tb11836.x Mash, 1985, Loss of M2 muscarinic receptors in the cerebral cortex in Alzheimer's disease and experimental cholinergic denervation, Science, 228, 1115, 10.1126/science.3992249 McKinney, 1982, Regulation of neocortical muscarinic receptors: effects of drug treatments and lesions, J. Neurosci., 2, 97, 10.1523/JNEUROSCI.02-01-00097.1982 McKinney, 1982, Somatostatin is not co-localized in cholinergic neurons innervating the rat cerebral cortex-hippocampal formation, Brain Res., 243, 169, 10.1016/0006-8993(82)91133-7 Mesulam, 1983, The cholinergic enervation of the cortex by the basal forebrain: cytochemistry and cortical connections of the septal area, diagonal band nuclei, nucleus basalis (substantia innominata) and hypothalamus in the rhesus monkey, J. Comp. Neurol., 214, 170, 10.1002/cne.902140206 Miyamoto, 1985, Lesioning of the rat basal forebrain leads to memory impairments in passive and active avoidance tasks, Brain Res., 328, 97, 10.1016/0006-8993(85)91327-7 Moroni, 1984, Studies on the content, synthesis and disposition of quinolinic acid in physiology and pathology, Clin. Neuropharmacol., 7, 448, 10.1097/00002826-198406001-00222 Murray, 1985, Learning and memory deficits after lesions of the nucleus basalis magnocellularis: reversal by physostigmine, Neuroscience, 14, 1025, 10.1016/0306-4522(85)90273-8 Murray, 1986, Pilocarpine and physostigmine attenuate spatial memory impairments produced by lesions of the nucleus basalis magnocellularis, Behav. Neurosci., 100, 23, 10.1037/0735-7044.100.1.23 Panzarino, 1986, Alzheimer's-like neuropathology in cortex and hippocampus induced by long-term nucleus basalis magnocellularis (NBM) lesioning in the rat, Soc. Neurosci. Abstr., 12, 943 Pearson, 1984, Hypertrophy of immunohistochemically identified cholinergic neurons of the basal nucleus of Meynert following ablation of the contralateral cortex in the rat, Brain Res., 311, 194, 10.1016/0006-8993(84)91418-5 Ridley, 1985, Effects of ibotenic acid lesions of the basal forebrain on serial reversal learning in the marmoset, Psychopharmacology, 86, 438, 10.1007/BF00427905 Ridley, 1986, Learning impairments following lesion of the basal nucleus of Meynert: modification by cholinergic drugs, Brain Res., 376, 108, 10.1016/0006-8993(86)90904-2 Rush, 1986, Reversal of scopolamine induced amnesia of passive avoidance by pre and post training naloxone, Psychopharmacology, 89, 296, 10.1007/BF00174363 Rye, 1984, Cortical projections arising from the basal forebrain: a study of cholinergic and noncholinergic components employing combined retrograde tracing and immunohistochemical localization of choline acetyltransferase, Neuroscience, 13, 627, 10.1016/0306-4522(84)90083-6 Salamone, 1984, Impairment in t-maze reinforced alternation performance following nucleus basalis magnocellularis lesions in rats, Behav. Brain Res., 13, 63, 10.1016/0166-4328(84)90030-5 Sano, 1987, Consistent improvement in memory with long-term oral physostigmine therapy in Alzheimer's disease, Neurology, 37, 333 Saper, 1985, Neuronal pathology in the nucleus basalis and associated cell groups in senile dementia of the Alzheimer type: possible role in cell loss, Neurology, 35, 1089, 10.1212/WNL.35.8.1089 Schwarcz, 1984, Excitotoxic models for neurodegenerative disorders, Life Sci., 35, 19, 10.1016/0024-3205(84)90148-6 Shimohama, 1987, Changes in β-adrenergic receptor subtypes in Alzheimer-type dementia, J. Neurochem., 48, 1215, 10.1111/j.1471-4159.1987.tb05649.x Sparks, 1986, Alzheimer's disease: monoamines and spiperone binding reduced in nucleus basalis, Ann. Neurol., 19, 602, 10.1002/ana.410190616 Spencer, 1985, Novel approaches in the study of acetylcholine function: neuropharmacology, neuroanatomy and behavior Summers, 1986, Oral tetrahydroaminoacridine in long-term treatment of senile dementia, Alzheimer type, N. Engl. J. Med., 315, 239, 10.1056/NEJM198611133152001 Sunderland, 1985, Pharmacological challenge strategies in Alzheimer's disease: basic and clinical issues, Psychopharmacol. Bull., 21, 676 Vogelsang, 1986, Use of the scopolamine treated rat as an animal model for Alzheimer's disease: amnestic effects, reductions in regional brain energy metabolism and reversal by the nootropic agent piracetam, Soc. Neurosci. Abstr., 12, 715 Walsh, 1984, AF64A, a cholinergic neurotoxin, selectively depletes acetylcholine in hippocampus and cortex and produces long-term passive avoidance and radial-arm maze deficits in the rat, Brain Res., 321, 91, 10.1016/0006-8993(84)90684-X Watson, 1985, Effects of bilateral ibotenate-induced lesions of the nucleus basalis magnocellularis upon selective cholinergic biochemical markers in the rat anterior cerebral cortex, Brain Res., 346, 387, 10.1016/0006-8993(85)90876-5 Weinberger, 1979, The effect of scopolamine on local glucose metabolism in rat brain, Brain Res., 177, 337, 10.1016/0006-8993(79)90784-4 Wenk, 1984, Nucleus basalis magnocellularis: optimal coordinates for selective reduction of choline acetyltransferase in frontal neocortex by ibotenic acid injection, Exp. Brain Res., 56, 335, 10.1007/BF00236289 Wenk, 1986, [3H]Ketanserin (serotonin type 2) binding increases in rat cortex following basal forebrain lesion with ibotenic acid, J. Neurochem., 47, 845, 10.1111/j.1471-4159.1986.tb00688.x Wenk, 1984, Recovery of neocortical choline acetyltransferase activity following ibotenic acid injection into the nucleus basalis of Meynert in rats, Brain Res., 293, 184, 10.1016/0006-8993(84)91468-9 Whishaw, 1985, Disruption of central cholinergic systems in the rat brain by basal forebrain lesions or atropine: effects on feeding, sensorimotor behavior, locomotor activity and spatial navigation, Behav. Brain Res., 17, 103, 10.1016/0166-4328(85)90023-3 Whitehouse, 1983, Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain, Science, 215, 1237, 10.1126/science.7058341 Wirsching, 1984, Differential effects of scopolamine on working and reference memory of rats in the radial maze, Pharmacol. Biochem. Behav., 20, 659, 10.1016/0091-3057(84)90180-1 Young, 1986, Studies of cortical glutamate receptors in nucleus basalis lesioned rats, Soc. Neurosci. Abstr., 12, 343