Angiogenic circular RNAs: A new landscape in cardiovascular diseases

Microvascular Research - Tập 129 - Trang 103983 - 2020
Tian-Rong Zhang1, Wei-Qiang Huang1
1Department of Geriatric Cardiology, Guangxi Key Laboratory Base of Precision Medicine in Cardio-cerebrovascular Diseases Control and Prevention, Guangxi Clinical Research Center for Cardio-cerebrovascular Diseases, The First Affiliated Hospital of Guangxi Medical University, Nanning, PR China

Tài liệu tham khảo

Abdelmohsen, 2017, Identification of HuR target circular RNAs uncovers suppression of PABPN1 translation by CircPABPN1, RNA Biol., 14, 361, 10.1080/15476286.2017.1279788 AbouHaidar, 2016, Novel coding, translation, and gene expression of a replicating covalently closed circular RNA of 220 nt, Proc. Natl. Acad. Sci. U. S. A., 113, E5252, 10.1073/pnas.1611407113 Ashwal-Fluss, 2014, circRNA biogenesis competes with pre-mRNA splicing, Mol. Cell, 56, 55, 10.1016/j.molcel.2014.08.019 Barbagallo, 2019, CircSMARCA5 regulates VEGFA mRNA splicing and angiogenesis in glioblastoma multiforme through the binding of SRSF1, Cancers, 11, 10.3390/cancers11020194 Barrett SP, Wang PL, J. S.Circular RNA biogenesis can proceed through an exon-containing lariat precursor.Elife 2015;9(4):e07540. Bentley, 2014, Coupling mRNA processing with transcription in time and space, Nat. Rev. Genet., 15, 163, 10.1038/nrg3662 Boeckel, 2015, Identification and characterization of hypoxia-regulated endothelial circular RNA, Circ. Res., 117, 884, 10.1161/CIRCRESAHA.115.306319 Burd, 2010, Expression of linear and novel circular forms of an INK4/ARF-associated non-coding RNA correlates with atherosclerosis risk, PLoS Genet., 6, 10.1371/journal.pgen.1001233 Cai L, 2019, Circular RNA Ttc3 regulates cardiac function after myocardial infarction by sponging miR-15b., J Mol Cell Cardiol, 130, 10, 10.1016/j.yjmcc.2019.03.007 Cao, 2018, High glucose-induced circHIPK3 downregulation mediates endothelial cell injury, Biochem. Biophys. Res. Commun., 507, 362, 10.1016/j.bbrc.2018.11.041 Chen, 2017, Circular RNA WDR77 target FGF-2 to regulate vascular smooth muscle cells proliferation and migration by sponging miR-124, Biochem. Biophys. Res. Commun., 494, 126, 10.1016/j.bbrc.2017.10.068 Chen, 2018, PRMT5 circular RNA promotes metastasis of urothelial carcinoma of the bladder through sponging miR-30c to induce epithelial–mesenchymal transition, Clin. Cancer Res., 24, 6319, 10.1158/1078-0432.CCR-18-1270 Cheng, 2019, Downregulation of hsa_circ_0068087 ameliorates TLR4/NF-κB/NLRP3 inflammasome-mediated inflammation and endothelial cell dysfunction in high glucose conditioned by sponging miR-197, Gene, 709, 1, 10.1016/j.gene.2019.05.012 Chou, 2010, EGFR promotes lung tumorigenesis by activating miR-7 through a Ras/ERK/Myc pathway that targets the Ets2 transcriptional repressor ERF, Cancer Res., 70, 8822, 10.1158/0008-5472.CAN-10-0638 Cocquerelle, 1993, Mis splicing yields circular RNA molecules, The FASEB, 7, 10.1096/fasebj.7.1.7678559 Conn, 2015, The RNA binding protein quaking regulates formation of circRNAs, Cell, 160, 1125, 10.1016/j.cell.2015.02.014 Dang, 2017, Circular RNA hsa_circ_0010729 regulates vascular endothelial cell proliferation and apoptosis by targeting the miR-186/HIF-1alpha axis, Biochem. Biophys. Res. Commun., 490, 104, 10.1016/j.bbrc.2017.05.164 Deng, 2015, miR-519d-mediated downregulation of STAT3 suppresses breast cancer progression, Oncol. Rep., 34, 2188, 10.3892/or.2015.4160 Ding, 2015, MiR-519d-3p suppresses invasion and migration of trophoblast cells via targeting MMP-2, PLoS One, 10, 10.1371/journal.pone.0120321 Du, 2017, Foxo3 circular RNA promotes cardiac senescence by modulating multiple factors associated with stress and senescence responses, Eur. Heart J., 38, 1402 F1, 2012, Endothelial progenitor cells in atherosclerosis, Front. Biosci., 17, 27 Geng, 2016, The circular RNA Cdr1as promotes myocardial infarction by mediating the regulation of miR-7a on its target genes expression, PLoS One, 11, 10.1371/journal.pone.0151753 Greene, 2017, Circular RNAs: biogenesis, function and role in human diseases, Front. Mol. Biosci., 4, 10.3389/fmolb.2017.00038 Guo, 2014, Expanded identification and characterization of mammalian circular RNAs, Genome Biol., 15, 409, 10.1186/s13059-014-0409-z H, 2016, MicroRNA-218 promotes high glucose-induced apoptosis in podocytes by targeting heme oxygenase-1, Biochem. Biophys. Res. Commun., 471, 582, 10.1016/j.bbrc.2016.02.028 Hall, 2019, Circ_Lrp6, a circular RNA enriched in vascular smooth muscle cells, acts as a sponge regulating miRNA-145 function, Circ. Res., 124, 498, 10.1161/CIRCRESAHA.118.314240 Hansen, 2011, miRNA-dependent gene silencing involving Ago2-mediated cleavage of a circular antisense RNA, EMBO J., 30, 4414, 10.1038/emboj.2011.359 Hansen, 2013, Natural RNA circles function as efficient microRNA sponges, Nature, 495, 384, 10.1038/nature11993 He, 2018, circ-SHKBP1 regulates the angiogenesis of U87 glioma-exposed endothelial cells through miR-544a/FOXP1 and miR-379/FOXP2 pathways, Mol. Ther.–Nucleic Acids, 10, 331, 10.1016/j.omtn.2017.12.014 He, 2019, MOV10 binding circ-DICER1 regulates the angiogenesis of glioma via miR-103a-3p/miR-382-5p mediated ZIC4 expression change, J. Exp. Clin. Cancer Res., 38, 9, 10.1186/s13046-018-0990-1 He, 2019, FUS/circ_002136/miR-138-5p/SOX13 feedback loop regulates angiogenesis in glioma, J. Exp. Clin. Cancer Res., 38, 65, 10.1186/s13046-019-1065-7 Ho, 2018, MiR-378 and MiR-1827 regulate tumor invasion, migration and angiogenesis in human lung adenocarcinoma by targeting RBX1 and CRKL, respectively, J. Cancer, 9, 331, 10.7150/jca.18188 Holdt, 2016, Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans, Nat. Commun., 7, 10.1038/ncomms12429 Hristov, 2008, Endothelial progenitor cells in vascular repair and remodeling, Pharmacol. Res., 58, 148, 10.1016/j.phrs.2008.07.008 Ivanov, 2015, Analysis of intron sequences reveals hallmarks of circular RNA biogenesis in animals, Cell Rep., 10, 170, 10.1016/j.celrep.2014.12.019 J, 2017, Integrative bioinformatics analysis identifies ROBO1 as a potential therapeutic target modified by miR-218 in hepatocellular carcinoma, Oncotarget, 8, 61327, 10.18632/oncotarget.18099 Jeck, 2014, Detecting and characterizing circular RNAs, Nat. Biotechnol., 32, 453, 10.1038/nbt.2890 Jeck, 2013, Circular RNAs are abundant, conserved, and associated with ALU repeats, Rna, 19, 141, 10.1261/rna.035667.112 Jin, 2019, Profiling and functional analysis of differentially expressed circular RNAs in high glucose-induced human umbilical vein endothelial cells, FEBS Open Bio, 9, 1640, 10.1002/2211-5463.12709 Kakudo, 2015, Hypoxia enhances proliferation of human adipose-derived stem cells via HIF-1a activation, PLoS One, 10, 10.1371/journal.pone.0139890 Kazerounian, 2018, Integration of pro- and anti-angiogenic signals by endothelial cells, Journal of Cell Communication and Signaling, 12, 171, 10.1007/s12079-017-0433-3 Kong, 2013, Placenta mesenchymal stem cell accelerates wound healing by enhancing angiogenesis in diabetic Goto-Kakizaki (GK) rats, Biochem. Biophys. Res. Commun., 438, 410, 10.1016/j.bbrc.2013.07.088 Lasda, 2016, Circular RNAs co-precipitate with extracellular vesicles: a possible mechanism for circRNA clearance, PLoS One, 11, 10.1371/journal.pone.0148407 Legnini, 2017, Circ-ZNF609 is a circular RNA that can be translated and functions in myogenesis, Mol. Cell, 66, 22, 10.1016/j.molcel.2017.02.017 Lei, 2019, Circular RNA: a novel biomarker and therapeutic target for human cancers, Int. J. Med. Sci., 16, 292, 10.7150/ijms.28047 Li, 2015, MicroRNA-107 contributes to post-stroke angiogenesis by targeting Dicer-1, Sci. Rep., 5, 13316, 10.1038/srep13316 Li, 2015, Exon-intron circular RNAs regulate transcription in the nucleus, Nat. Struct. Mol. Biol., 22, 256, 10.1038/nsmb.2959 Li, 2015, Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis, Cell Res., 25, 981, 10.1038/cr.2015.82 Li, 2015, Using circular RNA as a novel type of biomarker in the screening of gastric cancer, Clin. Chim. Acta, 444, 132, 10.1016/j.cca.2015.02.018 Li, 2017, Circular RNA hsa_circ_0003575 regulates oxLDL induced vascular endothelial cells proliferation and angiogenesis, Biomed. Pharmacother., 95, 1514, 10.1016/j.biopha.2017.09.064 Liang, 2017, MicroRNA-765 enhances the anti-angiogenic effect of CDDP via APE1 in osteosarcoma, J. Cancer, 8, 1542, 10.7150/jca.18680 Liu, 2017, Silencing of circular RNA-ZNF609 ameliorates vascular endothelial dysfunction, Theranostics, 7, 2863, 10.7150/thno.19353 Liu, 2019, Targeting pericyte–endothelial cell crosstalk by circular RNA-cPWWP2A inhibition aggravates diabetes-induced microvascular dysfunction, Proc. Natl. Acad. Sci., 116, 7455, 10.1073/pnas.1814874116 Liu, 2019, A two-circular RNA signature as a noninvasive diagnostic biomarker for lung adenocarcinoma, J. Transl. Med., 17, 50, 10.1186/s12967-019-1800-z Maass, 2017, A map of human circular RNAs in clinically relevant tissues, J. Mol. Med., 95, 1179, 10.1007/s00109-017-1582-9 Matluobi, 2018, Carvacrol promotes angiogenic paracrine potential and endothelial differentiation of human mesenchymal stem cells at low concentrations, Microvasc. Res., 115, 20, 10.1016/j.mvr.2017.08.003 Memczak, 2013, Circular RNAs are a large class of animal RNAs with regulatory potency, Nature, 495, 333, 10.1038/nature11928 Memczak, 2015, Identification and characterization of circular RNAs as a new class of putative biomarkers in human blood, PLoS One, 10, 10.1371/journal.pone.0141214 Ning, 2014, Hepatocyte nuclear factor 4alpha-nuclear factor-kappaB feedback circuit modulates liver cancer progression, Hepatology, 60, 1607, 10.1002/hep.27177 Pan, 2018, Human circular RNA0054633 regulates high glucoseinduced vascular endothelial cell dysfunction through the microRNA218/roundabout 1 and microRNA218/heme oxygenase1 axes, Int. J. Mol. Med., 42, 597 Pang, 2014, MiR-519d represses ovarian cancer cell proliferation and enhances cisplatin-mediated cytotoxicity in vitro by targeting XIAP, OncoTargets and therapy, 7, 587, 10.2147/OTT.S60289 Qu, 2017, The emerging landscape of circular RNA in life processes, RNA Biol., 14, 992, 10.1080/15476286.2016.1220473 Rana, 2018, Endothelial progenitor cells as molecular targets in vascular senescence and repair, Curr. Stem Cell Res. Ther., 13, 438, 10.2174/1574888X13666180502100620 Reddy, 2008, MicroRNA-7, a homeobox D10 target, inhibits p21-activated kinase 1 and regulates its functions, Cancer Res., 68, 8195, 10.1158/0008-5472.CAN-08-2103 Rey, 2010, Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodelling, Cardiovasc. Res., 86, 236, 10.1093/cvr/cvq045 Roskoski R, Jr.Vascular endothelial growth factor (VEGF) and VEGF receptor inhibitors in the treatment of renal cell carcinomas.Pharmacol. Res. 2017;120:116–32. Rossi, 2019, Circ-ZNF609 regulates G1-S progression in rhabdomyosarcoma, Oncogene, 38, 3843, 10.1038/s41388-019-0699-4 Rybak-Wolf, 2015, Circular RNAs in the mammalian brain are highly abundant, conserved, and dynamically expressed, Mol. Cell, 58, 870, 10.1016/j.molcel.2015.03.027 Salgado-Somoza, 2017, The circular RNA MICRA for risk stratification after myocardial infarction, Int. J. Cardiol., 17, 33 Salzman, 2012, Circular RNAs are the predominant transcript isoform from hundreds of human genes in diverse cell types, PLoS One, 7, 10.1371/journal.pone.0030733 Shan, 2017, Circular noncoding RNA HIPK3 mediates retinal vascular dysfunction in diabetes mellitus, Circulation, 136, 1629, 10.1161/CIRCULATIONAHA.117.029004 Shang, 2018, Alterations of circular RNAs in hyperglycemic human endothelial cells, Biochem. Biophys. Res. Commun., 499, 551, 10.1016/j.bbrc.2018.03.187 Shang, 2019, MicroRNA-148a-3p promotes survival and migration of endothelial cells isolated from Apoe deficient mice through restricting circular RNA 0003575, Gene, 711, 10.1016/j.gene.2019.143948 Simons, 2016, Mechanisms and regulation of endothelial VEGF receptor signalling, Nat. Rev. Mol. Cell Biol., 17, 611, 10.1038/nrm.2016.87 Song, 2017, Effect of circular ANRIL on the inflammatory response of vascular endothelial cells in a rat model of coronary atherosclerosis, Cell. Physiol. Biochem., 42, 1202, 10.1159/000478918 Srinivasan, 2015, Hypoxia-induced expression of phosducin-like 3 regulates expression of VEGFR-2 and promotes angiogenesis, Angiogenesis, 18, 449, 10.1007/s10456-015-9468-3 Starke, 2015, Exon circularization requires canonical splice signals, Cell Rep., 10, 103, 10.1016/j.celrep.2014.12.002 Sun Y, 2017, A Novel Regulatory Mechanism of Smooth Muscle α-actin Expression by NRG- 1/circACTA2/miR-548f-5p Axis, Circ Res, 121, 628, 10.1161/CIRCRESAHA.117.311441 Tang, 2017, CircRNA_000203 enhances the expression of fibrosis-associated genes by derepressing targets of miR-26b-5p, Col1a2 and CTGF, in cardiac fibroblasts, Sci. Rep., 7, 40342, 10.1038/srep40342 Vausort M, 2016, Myocardial Infarction- Associated Circular RNA Predicting Left Ventricular Dysfunction, J Am Coll Cardiol, 68, 1247, 10.1016/j.jacc.2016.06.040 Vrijsen, 2016, Exosomes from cardiomyocyte progenitor cells and mesenchymal stem cells stimulate angiogenesis via EMMPRIN, Adv. Healthc. Mater., 5, 2555, 10.1002/adhm.201600308 Wang, 2015, Efficient backsplicing produces translatable circular mRNAs, Rna, 21, 172, 10.1261/rna.048272.114 Wang, 2016, A circular RNA protects the heart from pathological hypertrophy and heart failure by targeting miR-223, Eur. Heart J., 37, 2602, 10.1093/eurheartj/ehv713 Wang, 2017, Circular RNA mediates cardiomyocyte death via miRNA-dependent upregulation of MTP18 expression, Cell Death Differ., 24, 1111, 10.1038/cdd.2017.61 Wang, 2019, Exosomal circRNAs: biogenesis, effect and application in human diseases, Mol. Cancer, 18, 116, 10.1186/s12943-019-1041-z WJ, 2013, Circular RNA (circRNA) in Alzheimer’s disease (AD), Front. Genet., 4, 307 WL, 2017, A landscape of circular RNA expression in the human heart, Cardiovasc. Res., 113, 298 Wu, 2019, Circular RNA circTADA2A promotes osteosarcoma progression and metastasis by sponging miR-203a-3p and regulating CREB3 expression, Mol. Cancer, 18, 73, 10.1186/s12943-019-1007-1 Wurdinger, 2008, miR-296 regulates growth factor receptor overexpression in angiogenic endothelial cells, Cancer Cell, 14, 382, 10.1016/j.ccr.2008.10.005 Xu, 2015, The circular RNA Cdr1as, via miR-7 and its targets, regulates insulin transcription and secretion in islet cells, Sci. Rep., 5, 12453, 10.1038/srep12453 Xu, 2019, circDiaph3 regulates rat vascular smooth muscle cell differentiation, proliferation, and migration, FASEB J., 33, 2659, 10.1096/fj.201800243RRR Xu, 2019, Elevation of circular RNA circ_0005230 facilitates cell growth and metastasis via sponging miR-1238 and miR-1299 in cholangiocarcinoma, Aging (Albany NY), 11, 1907, 10.18632/aging.101872 YF, 2015, Endothelial progenitor cells in ischemic stroke: an exploration from hypothesis to therapy, J. Hematol. Oncol., 8 Yu, 2016, The circular RNA Cdr1as act as an oncogene in hepatocellular carcinoma through targeting miR-7 expression, PLoS One, 11, 10.1371/journal.pone.0158347 Zeng, 2017, A circular RNA binds to and activates AKT phosphorylation and nuclear localization reducing apoptosis and enhancing cardiac repair, Theranostics, 7, 3842, 10.7150/thno.19764 Zhang, 2013, Circular intronic long noncoding RNAs, Mol. Cell, 51, 792, 10.1016/j.molcel.2013.08.017 Zhang, 2014, Complementary sequence-mediated exon circularization, Cell, 159, 134, 10.1016/j.cell.2014.09.001 Zhang, 2017, Identification and characterization of circular RNAs as a new class of putative biomarkers in diabetes retinopathy, Invest. Ophthalmol. Vis. Sci., 58, 6500, 10.1167/iovs.17-22698 Zhang, 2019, Exosome circRNA secreted from adipocytes promotes the growth of hepatocellular carcinoma by targeting deubiquitination-related USP7, Oncogene, 38, 2844, 10.1038/s41388-018-0619-z Zhao, 2015, VEGF silencing inhibits human osteosarcoma angiogenesis and promotes cell apoptosis via PI3K/AKT signaling pathway, Cell Biochem. Biophys., 73, 519, 10.1007/s12013-015-0692-7 Zhao, 2016, Hsa_circ_0054633 in peripheral blood can be used as a diagnostic biomarker of pre-diabetes and type 2 diabetes mellitus, Acta Diabetol., 54, 237, 10.1007/s00592-016-0943-0 Zhao, 2017, Peripheral blood circular RNA hsa_circ_0124644 can be used as a diagnostic biomarker of coronary artery disease, Sci. Rep., 7, 39918, 10.1038/srep39918 Zheng, 2016, Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs, Nat. Commun., 7, 10.1038/ncomms11215 Zhou, 2017, A novel identified circular RNA, circRNA_010567, promotes myocardial fibrosis via suppressing miR-141 by targeting TGF-beta1, Biochem. Biophys. Res. Commun., 487, 769, 10.1016/j.bbrc.2017.04.044 Zhu, 2017, hsa_circ_0013958: a circular RNA and potential novel biomarker for lung adenocarcinoma, FEBS J., 284, 2170, 10.1111/febs.14132