Anemia, leukocytosis and thrombocytosis as prognostic factors in patients with cervical cancer treated with radical chemoradiotherapy: A retrospective cohort study

Girinski, 1989, Prognostic value of hemoglobin concentrations and blood transfusions in advanced carcinoma of the cervix treated by radiation therapy: results of a retrospective study of 386 patients, Int J Radiat Oncol Biol Phys, 16, 37, 10.1016/0360-3016(89)90007-2 Winter, 2004, Association of hemoglobin level with survival in cervical carcinoma patients treated with concurrent cisplatin and radiotherapy: a Gynecologic Oncology Group Study, Gynecol Oncol, 94, 495, 10.1016/j.ygyno.2004.04.008 Grogan, 1999, The importance of hemoglobin levels during radiotherapy for carcinoma of the cervix, Cancer, 86, 1528, 10.1002/(SICI)1097-0142(19991015)86:8<1528::AID-CNCR20>3.0.CO;2-E Thomas, 2001, The effect of hemoglobin level on radiotherapy outcomes: the Canadian experience, Semin Oncol, 28, 60, 10.1016/S0093-7754(01)90215-5 Doll, 2013, The significance of tumoral ERCC1 status in patients with locally advanced cervical cancer treated with chemoradiation therapy: a multicenter clinicopathologic analysis, Int J Radiat Oncol Biol Phys, 85, 721, 10.1016/j.ijrobp.2012.06.021 Barkati, 2013, Hemoglobin level in cervical cancer: a surrogate for an infiltrative phenotype, Int J Gynecol Cancer, 23, 724, 10.1097/IGC.0b013e31828a0623 Fyles, 2000, Anemia, hypoxia and transfusion in patients with cervix cancer: a review, Radiother Oncol, 57, 13, 10.1016/S0167-8140(00)00245-0 Bishop, 2015, Relationship between low hemoglobin levels and outcomes after treatment with radiation or chemoradiation in patients with cervical cancer: has the impact of anemia been overstated?, Int J Radiat Oncol Biol Phys, 91, 196, 10.1016/j.ijrobp.2014.09.023 Banerjee, 2013, The prognostic significance of pretreatment leukocytosis in patients with anal cancer treated with radical chemoradiotherapy or radiotherapy, Dis Colon Rectum, 56, 1036, 10.1097/DCR.0b013e31829ab0d4 Tavares-Murta, 2010, Systemic leukocyte alterations are associated with invasive uterine cervical cancer, Int J Gynecol Cancer, 20, 1154, 10.1111/IGC.0b013e3181ef8deb Garcia-Arias, 2007, The prognostic significance of leukocytosis in cervical cancer, Int J Gynecol Cancer, 17, 465, 10.1111/j.1525-1438.2007.00816.x Mabuchi, 2011, Pretreatment leukocytosis is an indicator of poor prognosis in patients with cervical cancer, Gynecol Oncol, 122, 25, 10.1016/j.ygyno.2011.03.037 Qiu, 2010, Incidence of anemia, leukocytosis, and thrombocytosis in patients with solid tumors in China, Tumour Biol, 31, 633, 10.1007/s13277-010-0079-8 Cho, 2016, Tumor-related leukocytosis is associated with poor radiation response and clinical outcome in uterine cervical cancer patients, Ann Oncol, 27, 2067, 10.1093/annonc/mdw308 Escande, 2016, Neutrophilia in locally advanced cervical cancer: a novel biomarker for image-guided adaptive brachytherapy?, Oncotarget, 7, 74886, 10.18632/oncotarget.12440 Chassagne D, Dutreix A, Almond P, Burgers J, Busch M, Joslin C. ICRU Report No. 38, Dose and volume specification for reporting intracavitary therapy in gynaecology. Bethesda: International commissioning on radiation units and measurements; 1985. Demirci, 2012, Evaluation of treatment results and prognostic factors in early-stage cervical carcinoma patients treated with postoperative radiotherapy or radiochemotherapy, Eur J Gynaecol Oncol, 33, 62 Seo, 2011, Nomogram prediction of overall survival after curative irradiation for uterine cervical cancer, Int J Radiat Oncol Biol Phys, 79, 782, 10.1016/j.ijrobp.2009.11.054 Thomas, 2008, Phase III trial to evaluate the efficacy of maintaining hemoglobin levels above 12.0 g/dL with erythropoietin vs above 10.0 g/dL without erythropoietin in anemic patients receiving concurrent radiation and cisplatin for cervical cancer, Gynecol Oncol, 108, 317, 10.1016/j.ygyno.2007.10.011 Lee, 2012, Pretreatment neutrophil:lymphocyte ratio as a prognostic factor in cervical carcinoma, Anticancer Res, 32, 1555 Mizunuma, 2015, The pretreatment neutrophil-to-lymphocyte ratio predicts therapeutic response to radiation therapy and concurrent chemoradiation therapy in uterine cervical cancer, Int J Clin Oncol, 20, 989, 10.1007/s10147-015-0807-6 Dirican, 2015, Association of intratumoral tumor infiltrating lymphocytes and neutrophil-to- lymphocyte ratio are an independent prognostic factor in non-small cell lung cancer, Clin Respir J