Androgen receptors, 5 alpha-reductase activity and androgen-dependent proliferation of vascular smooth muscle cells

Ryoji Fujimoto1, Isao Morimoto1, Emiko Morita1, Hidekatsu Sugimoto2, Yukio Ito3, Sumiya Eto1
1First Department of Internal Medicine, University of Occupational and Environmental Health. 1-1, Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka 807, Japan
2Sugimoto Clinic, 13-6, 1chome, Nakasone, Kokuraminami-ku, Kitakyushu, Fukuoka 800-02, Japan
3Department of Medical Humanities, University of Occupational and Environmental Health. 1-1, Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka 807, Japan

Tài liệu tham khảo

McGill, 1979, Sex and atherosclerosis, Atherosclerosis Rev., 4, 157 Greger, 1990, High-density lipoprotein response to 5-alpha-dihydrotestosterone and testosterone in Macaca fascicularis: a hormone-responsive primate model for the study of atherosclerosis, Metabolism, 39, 919, 10.1016/0026-0495(90)90301-R Semmens, 1983, Relationship of plasma HDL-Cholesterol to testosterone, estradiol and sex-hormone-binding globulin levels in men and women, Metabolism, 32, 428, 10.1016/0026-0495(83)90002-1 1988, The recognition and management of hyperlipidemia in adults: a policy statement of the European Atherosclerosis Society, Eyr. Heart J., 9, 571, 10.1093/oxfordjournals.eurheartj.a062547 Fischer, 1985, A possible mechanims in arterial wall for mediation of sex difference in atherosclerosis, Expl Molec. Pathol., 43, 288, 10.1016/0014-4800(85)90066-8 Ross, 1971, The smooth muscle cell, J. cell Biol., 50, 172, 10.1083/jcb.50.1.172 Chomczynski, 1987, Single-step method of RNA isolation by acid guanidium triocyanate-phenol-chloroform extraction, Analyt. Biochem., 162, 156, 10.1016/0003-2697(87)90021-2 Chang, 1988, Structural analysis of complementary DNA and amino acid sequences of human and rat androgen receptors, 85, 7211 Griffin, 1977, Studies on the pathogenesis of the incomplete forms of androgen resistance in man, J. Clin. Endocr. Metab., 40, 1137, 10.1210/jcem-45-6-1137 Morimoto, 1992, Dihydrotestosterone accumulation in genital skin fibroblasts derived from elderly men with prostatic hyperplasia, J. Clin. Endocr. Metab., 75, 632, 10.1210/jc.75.2.632 Michel, 1980, Androgen receptor in rat skeletal muscle: characterization and physiological variations, Endocrinology, 107, 2088, 10.1210/endo-107-6-2088 Rajfer, 1980, Identification, partial characterization and age-related changes of a cytoplasmic androgen receptor in the rat penis, J. Steroid Biochem., 13, 1489, 10.1016/0022-4731(80)90064-3 Takane, 1990, Androgen receptor in rat penis is down regulated by androgen, J. Am. Physiol., 258, E46 Gonzalez, 1993, Up-regulation of the levels of androgen receptor and its mRNA by androgens in smooth-muscle cells from rat penis, Molec. Cell Endocr., 90, 219, 10.1016/0303-7207(93)90155-D Wilson, 1975, Metabolism of testicular androgens, Vol. 5, 491 Powers, 1975, A direct effect of testosterone on muscle cells in tissue culture, Endocrinology, 107, 1043, 10.1210/endo-97-4-1043 Wilson, 1970, The intranuclear metabolism of testosterone in the accessory organs of reproduction, Recent Prog. Horm. Res., 26, 309 Grino, 1990, Testosterone at high concentrations interacts with the human androgen receptor similarly to dihydrotestosterone, Endocrinology, 126, 1165, 10.1210/endo-126-2-1165 Prins, 1992, Androgen receptor expression and 5 alpha-reductase activity along the proximaldistal axis of the rat prostatic duct, Endocrinology, 130, 3066, 10.1210/en.130.5.3066 Kochakian, 1957, Influence of several steroids on the growth of individual muscles of the guinea pig, Endocrinology, 60, 607, 10.1210/endo-60-5-607 Neubauer, 1981, Actions of androgen and estrogen on guinea pig seminal vesicle epithelium and muscle, Endocrinology, 108, 680, 10.1210/endo-108-2-680 Gonzalez, 1991, Expression of androgen receptor gene in rat penile tissue and cells during sexual maturation, Endocrinology, 129, 1671, 10.1210/endo-129-3-1671 Nakao, 1981, Testosterone inhibits prostacyclin production by rat aortic smooth muscle cells in culture, Atherosclerosis, 39, 203, 10.1016/0021-9150(81)90070-8 Ross, 1981, Atherosclerosis; a problem of the biology of arterial wall cells and their interactions with blood components, Atherosclerosis, 1, 293