Androgen Deprivation Alters Attention to Sexually Provocative Visual Stimuli in Elderly Men

Sexual Medicine - Tập 5 - Trang e245-e254 - 2017
Jaime L. Palmer-Hague1, Vivian Tsang2, Charlenn Skead1, Richard J. Wassersug3,4, Eleni Nasiopoulos5, Alan Kingstone5
1Department of Psychology, Trinity Western University, Langley, BC, Canada
2Faculty of Science University of British Columbia, Vancouver BC, Canada
3Department of Medical Neuroscience, Dalhousie University, Halifax, NS, Canada
4Australian Research Centre in Sex, Health and Society, La Trobe University, Melbourne, VIC, Australia
5Department of Psychology, University of British Columbia, Vancouver, BC, Canada

Tóm tắt

Abstract Introduction Testosterone is known to regulate male sexual interest, but the exact way that androgens influence men's sexual cognition remains unclear. Aim To investigate the influence of androgen deprivation (AD) on visual responses to sexually suggestive stimuli in men treated for prostate cancer with AD therapy. Methods Patients with AD-treated prostate cancer, patients with prostate cancer not on AD therapy, and age-matched healthy control participants were exposed to images of male and female runway models fully or minimally clothed. Eye tracking was used to compare looking behavior among groups. Main Outcome Measures Proportion of fixations on fully clothed vs minimally clothed models and proportion of fixations on target areas of interest (ie, legs, chest, pelvis, and face) of fully clothed and minimally clothed models were analyzed and compared among groups. Results Although men not on AD exhibited a larger proportion of fixations on the minimally clothed compared with the fully clothed images, there was no difference between the 2 image types for men on AD. This was true regardless of whether the images depicted male or female models. Groups did not differ in their fixations to target areas of interest. Conclusion These results suggest that testosterone can influence men’s visual attention to sexual stimuli; specifically, AD can attenuate the time spent fixated on sexualized targets.

Tài liệu tham khảo

Santi, Molecular basis of androgen action on human sexual desire, Mol Cell Endocrinol Eisenegger, 2001, The role of testosterone in social interaction, Trends Cogn Sci, 15, 263, 10.1016/j.tics.2011.04.008 Hamilton, 2015, Social neuroendocrinology of status: a review and future directions, Adapt Hum Behav Physiol, 1, 202, 10.1007/s40750-015-0025-5 Ronay, 2010, The presence of an attractive woman elevates testosterone and physical risk taking in young men, Soc Psychol Person Sci, 1, 57, 10.1177/1948550609352807 Roney, 2003, Behavioral and hormonal responses of men to brief interactions with women, Evol Hum Behav, 24, 365, 10.1016/S1090-5138(03)00053-9 Bancroft, 2005, The endocrinology of sexual arousal, J Endocrinol, 186, 411, 10.1677/joe.1.06233 Corona, 2017, Testosterone and sexual function, Testosterone: from basic to clinical, 271, 10.1007/978-3-319-46086-4_14 Janssen, 2000, Automatic processes and the appraisal of sexual stimuli: toward and information processing model of sexual arousal, J Sex Res, 37, 8 Wenzlaff, 2015, Video-based eye tracking in sex research: a systematic literature review, J Sex Res, 21, 1 Watts, 2017, Pupil dilation to explicit and non-explicit sexual stimuli, Arch Sex Behav, 46, 155, 10.1007/s10508-016-0801-8 Lykins, 2008, Sex differences in visual attention to erotic and non-erotic stimuli, Arch Sex Behav, 37, 219, 10.1007/s10508-007-9208-x Nummenmaa, 2012, Gender and visibility of sexual cues influence eye movements while viewing faces and bodies, Arch Sex Behav, 41, 1439, 10.1007/s10508-012-9911-0 Dixson, 2011, Eye-tracking of men’s preferences for waist-to-hip ratio and breast size of women, Arch Sex Behav, 40, 43, 10.1007/s10508-009-9523-5 Garza, 2016, Male and female perception of physical attractiveness: an eye movement study, Evol Psychol, 4, 1 Rieger, 2015, Sexual arousal: the correspondence of eyes and genitals, Biol Psychiatry, 104, 56, 10.1016/j.biopsycho.2014.11.009 Huberman, 2015, Gender-specificity of women’s and men’s self-reported attention to sexual stimuli, J Sex Res, 52, 983 Dawson, 2016, Gender-specificity of initial and controlled visual attention to sexual stimuli in androphilic women and gynephilic men, PLoS One, 11, e0152785, 10.1371/journal.pone.0152785 Rupp, 2007, Relationship between testosterone and interest in sexual stimuli: the effect of experience, Horm Behav, 52, 581, 10.1016/j.yhbeh.2007.07.015 Zitsmann, 2001, Testosterone levels in healthy men and the relation to behavioural and physical characteristics: facts and constructs, Eur J Endocrinol, 144, 183, 10.1530/eje.0.1440183 Donovan, 2015, Psychological effects of androgen-deprivation therapy on men with prostate cancer and their partners, Cancer, 121, 4286, 10.1002/cncr.29672 Hamilton, 2016, The perspective of prostate cancer patients and patients’ partners on the psychological burden of androgen deprivation and the dyadic adjustment of prostate cancer couples, Psychooncology, 25, 823, 10.1002/pon.3930 Van Dam, 2016, Androgen deprivation therapy’s impact on the mood of prostate cancer patients as perceived by patients and the partners of patients, Psychooncology, 25, 848, 10.1002/pon.3932 Walker, 2013, Androgen deprivation therapy and maintenance of intimacy: a randomized controlled pilot study of an educational intervention for patients and their partners, Contemp Clin Trials, 34, 227, 10.1016/j.cct.2012.11.007 Wassersug, 2014, Androgen deprivation therapy: an essential guide for prostate cancer patients and their loved ones Bagatell, 1994, Effects of endogenous testosterone and estradiol on sexual behavior in young men, J Clin Endocrinol Metab, 78, 711 Schmidt, 2009, Pharmacologically induced hypogonadism and sexual function in young men and women, Neuropsychopharmacology, 34, 565, 10.1038/npp.2008.24 Jordan, 2014, Changed processing of visual sexual stimuli under GnRH-therapy—a single study in pedophilia using eye tracking and fMRI, BMC Psychiatry, 14, 142, 10.1186/1471-244X-14-142 de Jong, 2009, The role of attention in sexual arousal: implications for treatment of sexual dysfunction, J Sex Res, 46, 237 Risko, 2011, Eyes wide shut: implied social presence, eye tracking and attention, Atten Percept Psychophys, 73, 291, 10.3758/s13414-010-0042-1 Nasiopoulous, 2014, Wearable computing: will it make people more prosocial?, Br J Psychol, 106, 209, 10.1111/bjop.12080 Cella, 1993, The functional assessment of Cancer Therapy Scale: development and validation of the general measure, J Clin Oncol, 11, 570, 10.1200/JCO.1993.11.3.570 Wei, 2000, Development and validation of the Expanded Prostate Cancer Index Composite (EPIC) for comprehensive assessment of health-related quality of life in men with prostate cancer, Urology, 56, 899, 10.1016/S0090-4295(00)00858-X Capelleri, 2005, The Sexual Health Inventory for Men (SHIM): a 5-year review of research and clinical experience, Int J Impot Res, 17, 307, 10.1038/sj.ijir.3901327 Radloff, 1977, The CES-D scale: a self-report depression scale for research in the general population, Appl Psychol Meas, 1, 385, 10.1177/014662167700100306 Morley, 2000, Validation of a screening questionnaire for androgen deficiency in aging males, Metabolism, 49, 1239, 10.1053/meta.2000.8625 Traish, 2014, Adverse health effects of testosterone deficiency (TD) in men, Steroids, 88, 106, 10.1016/j.steroids.2014.05.010 Elliott, 2010, Androgen deprivation therapy for prostate cancer: recommendations to improve patient and partner quality of life, J Sex Med, 7, 2996 Wu, 2016, Cognitive and neurobehavioral symptoms in patients with non-metastatic prostate cancer treated with androgen deprivation therapy or observation: a mixed methods study, Soc Sci Med, 156, 80, 10.1016/j.socscimed.2016.03.016 Kornblith, 1994, Quality of life of patients with prostate cancer and their spouses. The value of a data base in clinical care, Cancer, 73, 2791, 10.1002/1097-0142(19940601)73:11<2791::AID-CNCR2820731123>3.0.CO;2-9 Tran, 2014, What do Canadian uro-oncologists believe patients should know about androgen deprivation therapy?, J Oncol Pharm Pract, 20, 199, 10.1177/1078155213495285 Navon, 2003, Advanced prostate cancer patients’ ways of coping with the hormonal therapy’s effect on body, sexuality, and spousal ties, Qual Health Res, 13, 1378, 10.1177/1049732303258016 Kim, 2008, Quality of life of couples dealing with cancer: didactic and individual adjustment among breast and prostate cancer survivors and their spousal caregivers, Ann Behav Med, 35, 230, 10.1007/s12160-008-9026-y Roesch, 2005, Coping with prostate cancer: a meta-analytic review, J Behav Med, 28, 281, 10.1007/s10865-005-4664-z Nelson, 2008, Cognitive effects of hormone therapy in men with prostate cancer, Cancer, 113, 1097, 10.1002/cncr.23658