Ancestral library identifies conserved reprogrammable liver motif on AAV capsid
Eric Zinn1,2,3,4, Carmen Unzu1,2,3,4, Pauline F. Schmit1,2,3,4, Heikki T. Turunen1,2,3,4, Nerea Zabaleta1,2,3,4, Julio Sanmiguel1,2,3,4, Allegra Fieldsend1,2,3,4, Urja Bhatt1,2,3,4, Cheikh Diop1,2,3,4, Erin Merkel1,2,3,4, Rakesh Gurrala1,2,3,4, Bryan Peacker4,5,6, Christopher Rios4,5,6, Kathleen Messemer4,5,6, Jennifer Santos1,2,3,4, Reynette Estelien1,2,3,4, Eva Andres-Mateos1,2,3,4, Amy J. Wagers4,5,6,7, Christopher Tipper1,2,3,4, Luk H. Vandenberghe1,2,3,4
1Grousbeck Gene Therapy Center, Schepens Eye Research Institute, Mass Eye and Ear, Boston, MA, USA
2Ocular Genomics Institute, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA
3The Broad Institute of Harvard and MIT, Cambridge, MA, USA
4Harvard Stem Cell Institute, Harvard University, Cambridge, MA, USA
5Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA
6Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA 02115, USA
7Joslin Diabetes Center, Boston, MA 02215, USA
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Cell Reports Medicine
Tập 3
100803
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