Analysis of reproducibility and robustness of OrganoPlate® 2-lane 96, a liver microphysiological system for studies of pharmacokinetics and toxicological assessment of drugs

Toxicology in Vitro - Tập 85 - Trang 105464 - 2022
Yuki Kato1,2, Alicia Y. Lim1, Courtney Sakolish1, Alan Valdiviezo1, Haley L. Moyer1, Philip Hewitt3, Piyush Bajaj4, Gang Han5, Ivan Rusyn1
1Department of Veterinary Physiology and Pharmacology Texas A&M University, College Station, TX 77843 USA
2Laboratory for Drug Discovery and Development, Shionogi Pharmaceutical Research Center, Shionogi & Co., Ltd., Osaka 561-0825, Japan
3Chemical and Preclinical Safety, Merck Healthcare KGaA, 64293 Darmstadt, Germany
4Global Investigative Toxicology, Preclinical Safety, Sanofi USA, MA 01701, USA
5Department of Epidemiology and Biostatistics, Texas A&M University, College Station, TX 77843, USA

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