Analysis of outcomes in radiation oncology: An integrated computational platform

Medical Physics - Tập 36 Số 5 - Trang 1680-1689 - 2009
Dezhi Liu1, M. Ajlouni2, Jian‐Yue Jin2, Samuel Ryu2, Farzan Siddiqui2, Assem Patel2, Benjamin Movsas2, Indrin J. Chetty2
1Department of Radiation Oncology, Henry Ford Health System, 2799 West Grand Boulevard, Detroit, Michigan 48202, USA.
2Department of Radiation Oncology, Henry Ford Health System, 2799 West Grand Boulevard, Detroit, Michigan 48202

Tóm tắt

Radiotherapy research and outcome analyses are essential for evaluating new methods of radiation delivery and for assessing the benefits of a given technology on locoregional control and overall survival. In this article, a computational platform is presented to facilitate radiotherapy research and outcome studies in radiation oncology. This computational platform consists of (1) an infrastructural database that stores patient diagnosis, IMRT treatment details, and follow‐up information, (2) an interface tool that is used to import and export IMRT plans in DICOM RT and AAPM/RTOG formats from a wide range of planning systems to facilitate reproducible research, (3) a graphical data analysis and programming tool that visualizes all aspects of an IMRT plan including dose, contour, and image data to aid the analysis of treatment plans, and (4) a software package that calculates radiobiological models to evaluate IMRT treatment plans. Given the limited number of general‐purpose computational environments for radiotherapy research and outcome studies, this computational platform represents a powerful and convenient tool that is well suited for analyzing dose distributions biologically and correlating them with the delivered radiation dose distributions and other patient‐related clinical factors. In addition the database is web‐based and accessible by multiple users, facilitating its convenient application and use.

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Medical Physics

Tập 36 Số 5

1680-1689

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