Analysis of Vascular Endothelial Growth Factor (VEGF) and a receptor subtype (KDR/flk-1) in the liver of rats exposed to riddelliine: a potential role in the development of hemangiosarcoma
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Arbiser, 2000, Overexpression of VEGF 121 in immortalized endothelial cells causes conversion to slowly growing angiosarcoma and high level expression of the VEGF receptors VEGFR-1 and VEGFR-2 in vivo, Am J Pathol, 156, 1469, 10.1016/S0002-9440(10)65015-8
Brown, 1996, Strong expression of kinase insert domain-containing receptor, a vascular permeability factor/vascular endothelial growth factor receptor in AIDS-associated Kaposi's sarcoma and cutaneous angiosarcoma, Am J Pathol, 148, 1065
CARMELIET, 2000, VEGF gene therapy: stimulating angiogenesis or angioma-genesis?, Nat Med, 6, 1102, 10.1038/80430
Chan, 2003, Toxicity and carcinogenicity of riddelliine in rats and mice, Toxicol Lett, 144, 295, 10.1016/S0378-4274(03)00240-6
Chan, 1994, Toxicity and carcinogenicity of riddelliine following 13 weeks of treatment to rats and mice, Toxicon, 32, 891, 10.1016/0041-0101(94)90368-9
Claffey, 1996, Expression of vascular permeability factor/vascular endothelial growth factor by melanoma cells increases tumor growth, angiogenesis, and experimental metastasis, Cancer Res, 56, 172
Copple, 2002, Endothelial cell injury and fibrin deposition in rat liver after monocrotaline exposure, Toxicol Sci, 65, 309, 10.1093/toxsci/65.2.309
Dougher, 1999, Autophosphorylation of KDR in the kinase domain is required for maximal VEGF-stimulated kinase activity and receptor internalization, Oncogene, 18, 1619, 10.1038/sj.onc.1202478
Dayanir, 2001, Identification of tyrosine residues in vascular endothelial growth factor receptor-2/flk-1 involved in activation of phosphatidylinositol 3-kinase and cell proliferation, J Biol Chem, 276, 17686, 10.1074/jbc.M009128200
Evans, 1997, The digestive system. II: The hepatobioliary system, 61
Furnus, 2003, Chronobiology of the proliferative events related to angiogenesis in mice liver regeneration after partial hepatectomy, Cell Biol Int, 27, 383, 10.1016/S1065-6995(02)00289-5
Gerber, 1998, Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol-3-kinase/Akt signal transduction pathway: requirement for flk-1/kdr activation, J Biol Chem, 273, 30336, 10.1074/jbc.273.46.30336
Gille, 2001, Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2), A reassessment using novel receptorspecific vascular endothelial growth factor mutants. J Biol Chem, 276, 3222
Hatva, 1996, Vascular growth factors and receptors in capillary hemangioblastomas and hemangiopericytomas, Am J Path, 148, 763
Herman, 2002, Rodent carcinogenicity with the thiazolidinedione antidiabetic agent troglitazone, Tox Sci, 68, 226, 10.1093/toxsci/68.1.226
Hsu, 1981, Protein A, avidin and biotin in immunohistochemistry, J Histochem Cytochem, 29, 1349, 10.1177/29.11.6172466
Lalich, 1997, Fibrin thrombosis in monocrotaline pyrrole-induced cor pulmonale in rats, Arch Pathol Lab Med, 101, 69
Lee, 2000, VEGF gene delivery to myocardium: deleterious effects of unregulated expression, Circulation, 102, 898, 10.1161/01.CIR.102.8.898
Millauer, 1993, High affinity Vegf binding and developmental expression suggest flk-1 as a major regulator of vasculogenesis and angiogenesis, Cell, 72, 835, 10.1016/0092-8674(93)90573-9
Mirsalis, 1993, Evaluation of the potential of riddelliine to induce unscheduled DNA synthesis, S-phase synthesis, or micronuclei following in vivo treatment with multiple doses, Environ. Mol. Mutagen., 21, 265, 10.1002/em.2850210310
Mochida, 1998, The mechanisms of hepatic sinusoidal endothelial cell regeneration: a possible communication system associated with vascular endothelial growth factor in liver cells, J Gastroenterol Hepatol, 13, S1, 10.1111/jgh.1998.13.s1.1
Molyneux, 1979, Chemistry of toxic range plants, Determination of pyrrolizidine alkaloid content and composition in Senecio species by nuclear magnetic resonance spectroscopy. J Agric Food Chem, 27, 494
Molyneux, 1991, Toxicity of pyrrolizidine alkaloids from Riddell groundsel (Senecio riddellii) to cattle, Am J Vet Res, 52, 146
National Toxicology Program: Toxicology and Carcinogenesis Studies of Riddelliine (CAS No. 23246-96-0) in F344/N Rats and B6C3F1 Mice (Gavage Studies). Board Draft, Technical Report 508, Public Health Service, U.S. Dept. of Health and Human Services, Bethesda, MD, 2001.
Nyska, 2002, The hepatic endothelial carcinogen riddelliine induces endothelial apoptosis, mitosis, S phase, p53, and hepatocytic vascular endothelial growth factor expression after shortterm exposure, Toxicol. Appl Pharmacol, 183, 153, 10.1006/taap.2002.9485
Ortega, 1999, Signal relays in the VEGF system, Front Biosci, 4, 141, 10.2741/Ortéga
Plate, 1993, Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis, Cancer Res, 53, 5822
Reindel, 1991, The effects of monocrotaline pyrrole on cultured bovine pulmonary artery endothelial and smooth muscle cells, Am J Pathol, 138, 707
Rosmorduc, 1999, Hepatocellular hypoxia-induced vascular endothelial growth factor expression and angiogenesis in experimental biliary cirrhosis, Am J Pathol, 155, 1065, 10.1016/S0002-9440(10)65209-1
Straume, 2001, Expression of vascular endothelial growth factor, its receptors (flt-1, kdr) and TSP-1 related to microvessel density and patient outcome in vertical growth phase melanomas, Am J Path, 159, 223, 10.1016/S0002-9440(10)61688-4
Williams, 2002, Toxicokinetics of riddelliine, a carcinogenic pyrrolizidine alkaloid, and metabolites in rats and mice, Toxicol Appl Pharmacol, 182, 98, 10.1006/taap.2002.9441
Yang, 2001, Metabolic activation of the tumorigenic pyrrolizidine alkaloid, riddelliine, leading to DNA adduct formation in vivo, Chem Res Toxicol, 14, 101, 10.1021/tx000150n
Zeng, 2001, Vascular permeability factor (VPF)/vascular endothelial growth factor (VEGF) receptor-1 down-modulates VPF/VEGF receptor-2-mediated endothelial cell proliferation, but not migration, through phosphatidylinositol 3-kinase-dependent pathways, J Biol Chem, 276, 26969, 10.1074/jbc.M103213200
Zeng, 2001, Tyrosine residues 951 and 1059 of vascular endothelial growth factor receptor-2 (KDR) are essential for vascular permeability factor/vascular endothelial growth factor-induced endothelium migration and proliferation, respectively, J Biol Chem, 276, 32714, 10.1074/jbc.M103130200