Analysis of Germline and Expressed T Cell Receptor Variable Region Genes in Crohn's Disease

Pathology - Research and Practice - Tập 192 - Trang 1022-1030 - 1996
C. Thurley1, B. Salh2, W. Kwan2, H. Freeman2, C. Blake Gilks1
1Department of Pathology and Laboratory Medicine, Vancouver Hospital and Health Sciences Center, University of British Columbia, Vancouver, B.C., Canada
2Division of Gastroenterology, Department of Medicine, Vancouver Hospital and Health Sciences Center, University of British Columbia, Vancouver, B.C., Canada

Tài liệu tham khảo

Bahler, 1992, Diversity of T-cell antigen receptor variable genes used by mycosis f ungoides cells, Am J Pathol, 140, 1 Balk, 1991, Oligoclonal expansion and CD1 recognition by human intestinal intraepithelial lymphocytes, Science, 253, 1411, 10.1126/science.1716785 Beall, 1993, Susceptibility for multiple sclerosis is determined, in part, by inheritance of a 175-kb region of the TcR Vß chain locus and HLA class II genes, J Neuroimmunol, 45, 53, 10.1016/0165-5728(93)90163-S Blin, 1976, Isolation of high molecular weight DNA, Nucleic Acids Research, 3, 2303, 10.1093/nar/3.9.2303 Blumberg, 1993, Human intestinal intraepithelial lymphocytes are derived from a limited number of T cell clones that utilize multiple Vß T cell receptor genes, J Immunol, 150, 5144 Breese, 1993, Interleukin 2 and interferon-gamma secreting T cells in normal and diseased intestinal mucosa, Immunology, 78, 127 Calkins, 1986, Epidemiology of inflammatory bowel disease, Epidemiologic Reviews, 8, 60, 10.1093/oxfordjournals.epirev.a036296 Charmley, 1990, T-cell receptor ß chain DNA polymorphism frequencies in healthy HLADR homozygotes, Tissue Antigens, 35, 157, 10.1111/j.1399-0039.1990.tb01773.x Chomczynski, 1987, Single-step method of RNA isolation by acid guanidinium thiocyanate-phenolchloroform extraction, Analytical Biochemistry, 162, 156, 10.1016/0003-2697(87)90021-2 Choy, 1990, Differential expression of CD25 (interleukin-2 receptor) on lamina propria T cells and macrophages in the intestinal lesions in Crohn's disease and ulcerative colitis, Gut, 31, 1365, 10.1136/gut.31.12.1365 Concannon, 1986, Diversity and strucure of human T-cell receptor ß-chain variable region genes, Proc Natl Acad Sci USA, 83, 6598, 10.1073/pnas.83.17.6598 Concannon, 1987, Human T cell receptor Vß gene polymorphism, J Exp Med 165: 1130-1140 13 Cuvelier C de Wever N Mielants H, de Vos M, Veys E, Roels H (1992) T-cells receptors in ileal mucosal biopsies of patients with Crohn disease and spondylarthropathy. Progress in Histo- and Cytochemistry, 26, 211 Davies, 1992, Evidence for selective accumulation of intrathyroidal T lymphocytes in human autoimmune thyroid disease based on T cell receptor V gene usage, J Clin Invest, 89, 157, 10.1172/JCI115556 Davis, 1988, T-cell antigen receptor genes and T-cell recognition, Nature, 334, 395, 10.1038/334395a0 Davis, 1990, T cell receptor gene diversity and selection, Annu Rev Biochem, 59, 475, 10.1146/annurev.bi.59.070190.002355 Deem, 1990, The CD8 Leu 7 + subset of T cells in Crohn's disease: distinction between cytotoxic and covert suppressor functions, Clin Exp Immunol, 80, 387, 10.1111/j.1365-2249.1990.tb03298.x Faloona, 1990 Fiocchi, 1988, Modulation of intestinal immune reactivity by interleukin 2, Phenotypic and functional analysis lymphokine activated killer cells from human intestinal mucosa. Dig Dis Sci, 331, 1305 Funkhouser, 1992, Differences in T cell receptor restriction fragment length polymorphisms in patients with rheumatoid arthritis, Arthritis and Rheumatism, 35, 465, 10.1002/art.1780350417 Germain, 1986, The ins and outs of antigen processin and presentation, Nature, 322, 687, 10.1038/322687a0 Gilks, 1991, Intratumoral T lymphocytes from small cleaved follicular center cell lymphomas show unrestricted T-cell receptor α-chain variable gene usae, Am J Pathol, 139, 25 Gilks, 1992, T cell receptor variable expression in cutaneous T cell lymphomas, J Cutan Pathol, 19, 21, 10.1111/j.1600-0560.1992.tb01554.x Gross, 1994, Distribution of dominant T cell receptor ß chains in human intestinal mucosa, J Exp Med, 180, 1337, 10.1084/jem.180.4.1337 Issacs, 1992, Cytokine messenger RNA profiles in inflammatory bowel disease mucosa detected by polymerase chain reaction amplification, Gastroenterology, 103, 1587, 10.1016/0016-5085(92)91182-4 Kagnoff, 1983, Association between Crohn's disease and immunoglobulin heavy chain (Gm) allotype, Gastroenterology, 85, 1044, 10.1016/S0016-5085(83)80069-9 Kaulfersch, 1988, Polyclonal nature of the intestinal mucosal lymphocyte populations in inflammatory bowel disease, Gastroenterology, 95, 364, 10.1016/0016-5085(88)90492-1 Konttinen, 1987, Lymphocyte activation in vivo in the intestinal mucosa of patients with Crohn's disease, J Clin Lab Immunol, 22, 59 Kusugami, 1989, Intestinal immune reactivity to interleukin 2 differs among Crohn's disease, ulcerative colitis and controls, Gastroenterology, 97, 1, 10.1016/0016-5085(89)91408-X Kusugami, 1995, Phenotypic and functional characterization of T-cell lines generated from colonoscopic biopsy specimens in patients with ulcerative colitis, Dig Dis Sci, 40, 198, 10.1007/BF02063967 Lockhart-Mummery, 1960, Crohn's disease (regional enteritis) of the large intestine and its distinction from ulcerative colitis, Gut, 1, 87, 10.1136/gut.1.2.87 Mantegazza, 1993, Analysis of T cell receptor repertoire of muscle-infiltrating T lymphocytes in polymyositis, Restricted V α/ß rearrangements may indicate antigen-driven selection. J Clin Invest, 91, 2880 Mayer, 1991, Expression of class II molecules on intestinal epithelial cells in humans, Differences between normal and inflammatory bowel disease. Gastroenterology, 100, 3 McCabe, 1993, Cytokine mRNA expression in intestine from normal and inflammatory bowel disease patients, Clin Immunol and Immunopathol, 66, 52, 10.1006/clin.1993.1007 Mullin, 1992, Increased interleukin-2 messenger RNA in the intestinal mucosal lesions of Crohn's disease but not ulcerative colitis, Gastroenterology, 102, 1620, 10.1016/0016-5085(92)91722-G Oksenberg, 1989, T-cell receptor Vα and Cα alleles associated with multiple sclerosis and myasthenia gravis, Proc Natl Acad Sci USA, 86, 988, 10.1073/pnas.86.3.988 Oksenberg, 1990, Limited heterogeneity of rearranged T-cell receptor Vα transcripts in brains of multiple sclerosis patients, Nature, 345, 344, 10.1038/345344a0 Ouyang, 1988, Expression of HLA-DR antigens in inflammatory bowel disease mucosa: role of intestinal lamina propria mononuclear cell-derived interferon γ, Dig Dis Sci, 33, 1528, 10.1007/BF01535942 Qiao, 1994, T cell receptor repertoire and mitotic responses of lamina propria T lymphocytes in inflammatory bowel disease, Clin Exp Immunol, 97, 303, 10.1111/j.1365-2249.1994.tb06085.x Pallone, 1987, Activation of peripheral blood and intestinal lamina propria lymphocytes in Crohn's disease. In vivo state of activation and in vitro response to stimulation as defined by the expression of early activation antigens, Gut, 28, 745, 10.1136/gut.28.6.745 Schreiber, 1991, Increased activation of isolated intestinal lamina propria mononuclear cells in inflammatory bowel disease, Gastroenterology, 101, 1020, 10.1016/0016-5085(91)90729-5 Selby, 1984, Intestinal lymphocyte subpopulations in inflammatory bowel disease; an analysis by immunohistiological and cell isolation techniques, Gut, 25, 32, 10.1136/gut.25.1.32 Shanahan, 1989, Enhanced peripheral blood T-cell cytotoxicity in inflammatory bowel disease, J Clin Immunol, 9, 55, 10.1007/BF00917128 Shohat, 1991, Genetics, 53 Sofaer, 1993, Crohn's disease: the genetic contribution, Gut, 34, 869, 10.1136/gut.34.7.869 Thurley, 1994, T cell receptor gene expression and genotypes in celiac disease, Pathobiol, 62, 311, 10.1159/000163924 Trejdosiewicz, 1989, Expression of T-cell receptors TcR1(γ/δ) and TcR2 (α/ß) in the human intestinal mucosa, Immunology, 68, 7 Van Kerckhove, 1992, Oligoclonality of human intestinal intraepithelial T cells, J Exp Med, 175, 57, 10.1084/jem.175.1.57 Williams, 1992, Restricted heterogeneity of T cell receptor transcripts in rheumatoid synovium, J Clin Invest, 90, 326, 10.1172/JCI115866 Winoto, 1986, Predominant use of a Vα gene segment in mouse T-cell receptors for cytochrome c, Nature, 324, 679, 10.1038/324679a0