Analysis of CCG Repeats in Huntingtin Gene among HD Patients and Normal Populations in Japan

Archives of Medical Research - Tập 39 - Trang 131-133 - 2008
Saeid Morovvati1,2, Masanori Nakagawa2, Mitsuhiro Osame2, Ali Karami1
1Research Center of Molecular Biology, Baqiyatallah Medical Sciences University, Tehran, Iran
2Third Department of Internal Medicine, Kagoshima University Faculty of Medicine, Sakuragaoka, Kagoshima City, Japan

Tài liệu tham khảo

1993, A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes, Cell, 72, 971, 10.1016/0092-8674(93)90585-E Gusella, 1983, A polymorphic DNA marker genetically linked to Huntington's disease, Nature, 306, 234, 10.1038/306234a0 Martin, 1986, Huntington's disease: pathogenesis and management, N Engl J Med, 315, 1267, 10.1056/NEJM198611133152006 Squitieri, 1994, DNA haplotype analysis of Huntington's diseases reveals clues to the origins and mechanisms of CAG expansion and reasons for geographic variations of prevalence, Hum Mol Genet, 3, 2103, 10.1093/hmg/3.12.2103 Harper, 1992, The epidemiology of Huntington's disease, Hum Genet, 89, 365, 10.1007/BF00194305 Nakashima, 1996, Epidemiological and genetic studies of Huntington's disease in the San-in area of Japan, Neuroepidemiology, 15, 126, 10.1159/000109899 Rubinsztein, 1993, Analysis of the huntingtin gene reveals a trinucleotide-length polymorphism in the region of the gene that contains two CCG-rich stretches and a correlation between decreased age of onset of Huntington's disease and CAG repeat number, Hum Mol Genet, 2, 1713, 10.1093/hmg/2.10.1713 Barron, 1994, A single allele from the polymorphic CCG rich sequence immediately 3′ to the unstable CAG trinucleotide in the IT15 cDNA shows almost complete disequilibrium with Huntington's disease chromosomes in the Scottish population, Hum Mol Genet, 3, 173, 10.1093/hmg/3.1.173 Pramanik, 2000, Analysis of CAG and CCG repeats in Huntingtin gene among HD patients and normal populations of India, Eur J Hum Genet, 8, 678, 10.1038/sj.ejhg.5200515 Norremolle, 1993, Trinucleotide repeats elongation in the Huntingtin gene in Huntington's disease patients from 71 Danish families, Hum Mol Genet, 2, 1475, 10.1093/hmg/2.9.1475 Warner, 1993, A new polymerase chain reaction (PCR) assay for the trinucleotide repeat that is unstable and expanded on Huntington's disease chromosomes, Mol Cell Probes, 7, 235, 10.1006/mcpr.1993.1034 Masuda, 1995, Analysis of triplet repeats in the huntingtin gene in Japanese families affected with Huntington's disease, J Med Genet, 32, 701, 10.1136/jmg.32.9.701 Hećimović, 2002, Genetic background of Huntington's disease in Croatia: molecular analysis of CAG, CCG, and 2642 (E2642del) polymorphisms, Hum Mutat, 20, 233, 10.1002/humu.9055 Almqvist, 1995, Ancestral differences in the distribution of the Δ2642 glutamic acid polymorphism is associated with varying CAG repeat lengths on normal chromosomes: insight into the genetic evolution of Huntington's disease, Hum Mol Genet, 4, 207, 10.1093/hmg/4.2.207 Andrew, 1995, Origins and evolution of Huntington's disease chromosomes, Neurodegeneration, 4, 239, 10.1016/1055-8330(95)90013-6 Adachi, 1999, Population genetic study of Huntington's disease–prevalence and founder's effect in the San-in area, western Japan, Nippon Rinsho, 57, 900