An experimental study using 3-aminoproplymethyldiethoxysilane (APMDS) to improve biocompatibility of NR latex film

Springer Science and Business Media LLC - Tập 26 - Trang 125-137 - 2023
Nurulhuda Abdullah1, Nurul Hayati Yusof1, Shabinah Filza Mohd Sharib1, Siti Nor Qamarina Manaf1, Tajul Anuar Yaakob1, Kok Lang Mok1
1Rubber Research Institute of Malaysia, Malaysia Rubber Board, Sungai Buloh, Malaysia

Tóm tắt

To improve the biocompatibility of dipped films from natural rubber latex (NRL) without compromising physical strength, high ammoniated NRL (HA-NRL) compounding formulations were devised by manipulating the amount of compounding ingredients and additive materials. In this study, the compatibility of 3-aminoproplymethyldiethoxysilane (APMDS) with calcium carbonate (CaCO3) filler in zinc diethyldithiocarbamate (ZDEC) accelerated HA-NRL formulas were explored. It was found that ZDEC residue detected using High-Performance Liquid Chromatography (HPLC) was less than 6 μ/g in all NRL-dipped films. Furthermore, the cytotoxicity response of the films showed a lower toxicity effect in the presence of APMDS. The occurrence of chemical interactions between APMDS, CaCO3 and crosslinked NR was confirmed by the Attenuated Total Reflectance-Fourier Transmittance Infra-Red (ATR-FTIR) spectrometer. Interestingly, the physical strength of NRL-dipped film was greatly improved when APMDS was incorporated together with CaCO3 at a low dosage of ZDEC. This may be due to the adequate physical interaction between the APMDS-surface-modified filler particles and APMDS-surface-modified rubber particles. Overall, a biocompatible NRL film with satisfactory physical strength, low ZDEC residue and low cytotoxicity was achieved by employing a low dosage of ZDEC in the presence of APMDS and CaCO3.

Tài liệu tham khảo

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