An association between human papillomavirus 16/18 deoxyribonucleic acid in peripheral blood with p16 protein expression in neoplastic cervical lesions

Parkin, 2001, Estimating the world cancer burden: Globocan 2000, Int J Cancer, 94, 153, 10.1002/ijc.1440 zur Hausen, 2000, Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis, J Natl Cancer Int, 92, 690, 10.1093/jnci/92.9.690 Monsonego, 2004, Cervical cancer control, priorities and new directions, Int J Cancer, 108, 329, 10.1002/ijc.11530 Bosch, 2002, The causal relation between human papillomavirus and cervical cancer, J Clin Pathol, 55, 244, 10.1136/jcp.55.4.244 Dalstein, 2003, Persistence and load of high-risk HPV are predictors for development of high-grade cervical lesions: a longitudinal French cohort study, Int J Cancer, 106, 396, 10.1002/ijc.11222 Durst, 1992, Human papillomavirus type (HPV 16) gene expression and DNA replication in cervical neoplasia: analysis by in situ hybridisation, Virology, 189, 132, 10.1016/0042-6822(92)90688-L Scheffer, 1993, The HPV-16 E6 and E6-AP complex function as an ubiquitin-protein ligase in the ubiquitination of p53, Cell, 75, 495, 10.1016/0092-8674(93)90384-3 Chellappan, 1992, Adenovirus E1A simian virus 40 tumor antigen and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product, Proc Natl Acad Sci USA, 89, 4549, 10.1073/pnas.89.10.4549 Nevins, 1992, E2F: a link between the Rb tumor suppressor protein and viral oncoproteins, Science, 258, 424, 10.1126/science.1411535 Sherr, 1996, Cancer cell cycles, Science, 274, 1672, 10.1126/science.274.5293.1672 Harbour, 2000, Rb function in cell-cycle regulation and apoptosis, Nat Cell Biol, 2, 65, 10.1038/35008695 zur Hausen, 2002, Papillomaviruses and cancer: from basic studies to clinical application, Nat Rev Cancer, 2, 342, 10.1038/nrc798 Khleif, 1996, Inhibition of cyclin D-CDK4/CDK6 is associated with an E2F-mediated induction of cyclin kinase inhibitor activity, Proc Natl Acad Sci USA, 93, 4350, 10.1073/pnas.93.9.4350 Li, 1994, Transcriptional repression of the D-type cyclin-dependent kinas inhibitor p16 by the retinoblastoma susceptibility gene product pRb, Cancer Res, 54, 6078 Kim, 1998, Underexpression of cyclin-dependent kinase (CDK) inhibitors in cervical carcinoma, Gynecol Oncol, 71, 38, 10.1006/gyno.1998.5134 Nuovo, 1999, In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis, Proc Natl Acad Sci USA, 96, 12754, 10.1073/pnas.96.22.12754 Sano, 1998, Expression status of p16 protein is associated with human papillomavirus oncogenic potential in cervical and genital lesions, Am J Pathol, 153, 1741, 10.1016/S0002-9440(10)65689-1 Klaes, 2001, Overexpression of p16INK4A as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri, Int J Cancer, 92, 276, 10.1002/ijc.1174 Nieh, 2003, Expression of p16INK4A in Papanicolaou smears containing atypical squamous cells of undetermined significance from the uterine cervix, Gynecol Oncol, 91, 201, 10.1016/S0090-8258(03)00479-7 Pao, 1997, Detection of human papillomavirus mRNA and cervical cancer patients with metastasis, J Clin Oncol, 115, 1008, 10.1200/JCO.1997.15.3.1008 Pornthanakasem, 2001, Human papillomavirus DNA in plasma of patients with cervical cancer, BMC Cancer, 1, 1, 10.1186/1471-2407-1-2 Hsu, 2003, Clinical significance of serum human papillomavirus DNA in cervical carcinoma, Obstet Gynecol, 102, 1344, 10.1016/j.obstetgynecol.2003.08.023 Liu, 2001, Low incidence of HPV DNA in sera of pretreatment cervical cancer patients, Gynecol Oncol, 82, 269, 10.1006/gyno.2001.6289 Dong, 2002, Detection and quantification of human papillomavirus DNA in the plasma of patients with cervical carcinoma, Cancer Epidemiol BioMarkers Prev, 11, 3 Chiou, 2003, The presence of human papillomavirus type 16/18 DNA in blood circulation may act as a risk marker of lung cancer in Taiwan, Cancer, 97, 1558, 10.1002/cncr.11191 Solomon, 2002, The 2001 Bethesda System: terminology for reporting results of cervical cytology, J Am Med Assoc, 287, 2114, 10.1001/jama.287.16.2114 Creasman, 1995, New gynecologic cancer staging, Gynecol Oncol, 58, 157, 10.1006/gyno.1995.1203 Fujinaga, 1991, Simultaneous detection and typing of genital human papillomavirus DNA using the polymerase chain reaction, J Gen Virol, 72, 1039, 10.1099/0022-1317-72-5-1039 Yoshino, 1998, Aberrant fhit transcripts in squamous cell carcinoma of the uterine cervix, Int J Cancer, 76, 171, 10.1002/(SICI)1097-0215(19980413)76:2<176::AID-IJC2>3.0.CO;2-U Ke, 1999, Expression of human papillomavirus E7 mRNA in human oral and cervical neoplasia and cell lines, Oral Oncol, 35, 415, 10.1016/S1368-8375(99)00015-9 Capone, 2000, Detection and quantitation of Human Papillomavirus (HPV) DNA in the sera of patients with HPV-associated head and neck squamous cell carcinoma, Clin Cancer Res, 6, 4171 Cheng, 2001, The association of human papillomavirus 16/18 infection with lung cancer among nonsmoking Taiwanese women, Cancer Res, 61, 2799 Widschwendter, 2003, Human papillomavirus DNA in sera of cervical cancer patients as tumor marker, Cancer Lett, 202, 231, 10.1016/j.canlet.2003.09.006 Pao, 1991, Identification of human papillomavirus DNA sequences in peripheral blood mononuclear cells, Am J Clin Pathol, 95, 540, 10.1093/ajcp/95.4.540 Decker, 1996, Detection of the latent form of Epstein–Barr virus DNA in the peripheral blood of healthy individuals, J Virol, 70, 3286, 10.1128/JVI.70.5.3286-3289.1996 Lin, 2001, Detection of Epstein–Barr virus DNA in the peripheral-blood cells of patients with nasopharyngeal carcinoma: relationship to distant metastasis and survival, J Clin Oncol, 19, 2607, 10.1200/JCO.2001.19.10.2607 Cains, 1995, Frequency of homozygous deletion at p16/CDKN2 in primary human tumors, Nat Genet, 11, 210, 10.1038/ng1095-210 Geradts, 1996, High frequency of aberrant p16 INK4a expression in human breast cancer, Am J Pathol, 149, 15