An Unexpected Adverse Drug Effect

Journal of Midwifery and Women's Health - Tập 48 - Trang 67-68 - 2003
Cara J. Krulewitch

Tóm tắt

Adverse drug‐drug interactions can occur between active and/or inactive ingredients in different formulations. The occurrence of a disulfiram reaction that developed postpartum following a 7‐day course of metronidazole is presented. The case is presented, followed by a discussion of the mechanism of action and treatment. Recommendations for prevention of adverse drug effects are reviewed.

Tài liệu tham khảo

Fontaine P, 2000, Intrathecal narcotics are associated with prolonged second‐stage labor and increased oxytocin use, J Fam Pract, 49, 515 10.1097/00000539-199612000-00017 10.1097/00000539-200005000-00030 10.1097/00000539-199702000-00019 10.1345/aph.19118 Edwards DL, 1986, Disulfiram‐like reaction associated with intravenous trimethoprim‐sulfamethoxazole and metronidazole, Clin Pharmacy, 999 Hardman JG, 1996, Goodman & Gilman's: the pharmacological basis of therapeutics