An Isoquinolinium Derivative Selectively Inhibits MAPK Spc1 of the Stress-Activated MAPK Cascade of Schizosaccharomyces pombe
Tài liệu tham khảo
Garrington, 1999, Organization and regulation of mitogen-activated protein kinase signaling pathways, Curr. Opin. Cell Biol., 11, 211, 10.1016/S0955-0674(99)80028-3
Chang, 2001, Mammalian MAP kinase signalling cascades, Nature, 410, 37, 10.1038/35065000
Weston, 2002, Signal transduction: MAP kinase signaling specificity, Science, 296, 2345, 10.1126/science.1073344
Dudley, 1995, A synthetic inhibitor of the mitogen-activated protein kinase cascade, Proc. Natl. Acad. Sci. USA, 92, 7686, 10.1073/pnas.92.17.7686
Alessi, 1995, PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo, J. Biol. Chem., 270, 27489, 10.1074/jbc.270.46.27489
Favata, 1998, Identification of a novel inhibitor of mitogen-activated protein kinase kinase, J. Biol. Chem., 273, 18623, 10.1074/jbc.273.29.18623
Gum, 1998, Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket, J. Biol. Chem., 273, 15605, 10.1074/jbc.273.25.15605
Nemoto, 1998, Induction of apoptosis by SB202190 through inhibition of p38β mitogen-activated protein kinase, J. Biol. Chem., 273, 16415, 10.1074/jbc.273.26.16415
Bennett, 2001, SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase, Proc. Natl. Acad. Sci. USA, 98, 13681, 10.1073/pnas.251194298
Gotoh, 1993, Schizosaccharomyces pombe Spk1 is a tyrosine-phosphorylated protein functionally related to Xenopus mitogen-activated protein kinase, Mol. Cell. Biol., 13, 6427, 10.1128/MCB.13.10.6427
Hughes, 1993, Complementation of byr1 in fission yeast by mammalian MAP kinase kinase requires coexpression of Raf kinase, Nature, 364, 349, 10.1038/364349a0
Masuda, 1995, Protein kinase Byr2 is a target of Ras1 in the fission yeast Schizosaccharomyces pombe, J. Biol. Chem., 270, 1979, 10.1074/jbc.270.5.1979
Samejima, 1997, Multiple modes of activation of the stress-responsive MAP kinase pathway in fission yeast, EMBO J., 16, 6162, 10.1093/emboj/16.20.6162
Samejima, 1998, The fission yeast mitotic regulator win1+ encodes an MAP kinase kinase kinase that phosphorylates and activates Wis1 MAP kinase kinase in response to high osmolarity, Mol. Biol. Cell, 9, 2325, 10.1091/mbc.9.8.2325
Degols, 1996, Activation and regulation of the Spc1 stress-activated protein kinase in Schizosaccharomyces pombe, Mol. Cell. Biol., 16, 2870, 10.1128/MCB.16.6.2870
Sengar, 1997, Mkh1, a MEK kinase required for cell wall integrity and proper response to osmotic and temperature stress in Schizosaccharomyces pombe, Mol. Cell. Biol., 17, 3508, 10.1128/MCB.17.7.3508
Zaitsevskaya-Carter, 1997, Spm1, a stress-activated MAP kinase that regulates morphogenesis in S. pombe, EMBO J., 16, 1318, 10.1093/emboj/16.6.1318
Loewith, 2000, Skh1, the MEK component of the mkh1 signaling pathway in Schizosaccharomyces pombe, J. Cell Sci., 113, 153, 10.1242/jcs.113.1.153
Widmann, 1999, Mitogen activated protein kinase: conservation of a three-kinase module from yeast to human, Physiol. Rev., 79, 143, 10.1152/physrev.1999.79.1.143
Hartwell, 1997, Integrating genetic approaches into the discovery of anticancer drugs, Science, 278, 1064, 10.1126/science.278.5340.1064
Bishop, 2000, A chemical switch for inhibitor-sensitive alleles of any protein kinase, Nature, 407, 395, 10.1038/35030148
Heitman, 1991, Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast, Science, 253, 905, 10.1126/science.1715094
Heitman, 1991, FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae, Proc. Natl. Acad. Sci. USA, 88, 1948, 10.1073/pnas.88.5.1948
Cardenas, 1999, Antifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug action, Clin. Microbiol. Rev., 12, 583, 10.1128/CMR.12.4.583
Tropschug, 1989, Sensitivity to cyclosporin A is mediated by cyclophilin in Neurospora crassa and Saccharomyces cerevisiae, Nature, 342, 953, 10.1038/342953a0
Breuder, 1994, Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains, Proc. Natl. Acad. Sci. USA, 91, 5372, 10.1073/pnas.91.12.5372
Gray, 1998, Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors, Science, 281, 533, 10.1126/science.281.5376.533
Jang, 2002, Selective inhibition of MAPKK Wis1 in the stress-activated MAPK cascade of Schizosaccharomyces pombe by novel berberine derivatives, J. Biol. Chem., 277, 12388, 10.1074/jbc.M111018200
Parsons, 1994, Regulation of calcineurin phosphatase activity and interaction with the FK 506-FK 506 binding protein complex, J. Biol. Chem., 269, 19610, 10.1016/S0021-9258(17)32213-5
Hohmann, 2002, Osmotic stress signaling and osmoadaptation in yeasts, Microbiol. Mol. Biol. Rev., 66, 300, 10.1128/MMBR.66.2.300-372.2002
Nguyen, 2006, Heat shock-induced activation of stress MAP kinase is regulated by theronine- and tyrosine-specific phosphatases, Genes Dev., 13, 1653, 10.1101/gad.13.13.1653
Wilson, 1997, The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase, Chem. Biol., 4, 423, 10.1016/S1074-5521(97)90194-0
Eyers, 1998, Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution, Chem. Biol., 5, 321, 10.1016/S1074-5521(98)90170-3
Tanoue, 2000, A conserved docking motif in MAP kinases common to substrates, activators and regulators, Nat. Cell Biol., 2, 110, 10.1038/35000065
Chang, 2002, Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b, Mol. Cell, 9, 1241, 10.1016/S1097-2765(02)00525-7
Wang, 1998, Structural basis of inhibitor selectivity in MAP kinases, Structure, 6, 1117, 10.1016/S0969-2126(98)00113-0
Shiozaki, 1995, Cell-cycle control linked to extracellular environment by MAP kinase pathway in fission yeast, Nature, 378, 739, 10.1038/378739a0
Gachet, 2001, A MAP kinase-dependent actin checkpoint ensures proper spindle orientation in fission yeast, Nature, 412, 352, 10.1038/35085604
Tatebe, 2003, Identification of Cdc37 as a novel regulator of the stress-responsive mitogen-activated protein kinase, Mol. Biol. Cell, 23, 5132, 10.1128/MCB.23.15.5132-5142.2003
Westwood, 2004, Fission yeast Cdc37 is required for multiple cell cycle functions, Mol. Genet. Genomics, 271, 82, 10.1007/s00438-003-0958-4
Turnbull, 2005, Cdc37 maintains cellular viability in Schizosaccharomyces pombe independently of interactions with heat-shock protein 90, FEBS J., 272, 4129, 10.1111/j.1742-4658.2005.04825.x
Zhang, 2004, Hsp90/p50cdc37 is required for mixed-lineage kinase (MLK) 3 signaling, J. Biol. Chem., 279, 19457, 10.1074/jbc.M311377200
Turnbull, 2006, Activity of Cdc2 and its interaction with the cyclin Cdc13 depend on the molecular chaperone Cdc37 in Schizosaccharomyces pombe, J. Cell Sci., 119, 292, 10.1242/jcs.02729
Tanoue, 2002, Docking interactions in the mitogen-activated protein kinase cascades, Pharmacol. Ther., 93, 193, 10.1016/S0163-7258(02)00188-2
Tanoue, 2003, Molecular recognitions in the MAP kinase cascades, Cell. Signal., 15, 455, 10.1016/S0898-6568(02)00112-2
Roux, 2004, ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions, Microbiol. Mol. Biol. Rev., 68, 320, 10.1128/MMBR.68.2.320-344.2004
Moreno, 1991, Molecular genetic analysis of fission yeast Schizosaccharomyces pombe, Methods Enzymol., 194, 795, 10.1016/0076-6879(91)94059-L
Okazaki, 1990, High-frequency transformation method and library transducing vectors for cloning mammalian cDNAs by trans-complementation of Schizosaccharomyces pombe, Nucleic Acids Res., 18, 6485, 10.1093/nar/18.22.6485
Maundrell, 1993, Thiamine-repressible expression vectors pREP and pRIP for fission yeast, Gene, 123, 127, 10.1016/0378-1119(93)90551-D
Frédérique, 1998, Phosphorylation and association with the transcription factor Atf1 regulate localization of Spc1/Sty1 stress-activated kinase in fission yeast, Genes Dev., 12, 1464, 10.1101/gad.12.10.1464
Javerzat, 1996, Fission yeast genes which disrupt mitotic chromosome segregation when overexpressed, Nucleic Acids Res., 24, 4676, 10.1093/nar/24.23.4676