An Endocytic Pathway Essential for Renal Uptake and Activation of the Steroid 25-(OH) Vitamin D3

Cell - Tập 96 Số 4 - Trang 507-515 - 1999
Anders Nykjær1, Duska Dragun2, Diego J. Walther3, Henrik Vorum4, Christian Jacobsen4, Joachim Herz5, F. Melsen6, Erik I. Christensen7, Thomas E. Willnow3
1Max Delbrüeck Center for Molecular Medicine, Berlin, Germany
2Franz-Volhard-Clinic, 13125 Berlin, Germany
3Max Delbrueck Center for Molecular Medicine, 13125 Berlin, Germany
4Department of Medical Biochemistry, Aarhus, Denmark
5University of Texas Southwestern Medical Center, Dallas, Texas 75235, USA.
6Department of Pathology, Aarhus University Hospital, 8000 Aarhus, Denmark.
7Department of Cell Biology, University of Aarhus, Aarhus, Denmark

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Bikle, 1985, Serum protein binding of 1, 25-dihydroxyvitamin D, J. Clin. Endocrinol. Metab., 61, 969, 10.1210/jcem-61-5-969

Bikle, 1986, Assessment of the free fraction of 25-hydroxyvitamin D in serum and its regulation by albumin and the vitamin D-binding protein, J. Clin. Endocrinol. Metab., 63, 954, 10.1210/jcem-63-4-954

Christensen, 1995, Segmental distribution of the endocytosis receptor gp330 in renal proximal tubules, Eur. J. Cell. Biol., 66, 349

Cooke, N.E., Safadi, F.F., Magiera, H.M., Thornton, P., Hollis, B., Liebhaber, S.A., Gentile, M., and Haddad, J.G. (1997). Biological consequence of vitamin D binding protein deficiency in a mouse model. In Vitamin D, A.W. Norman, R. Bouillon, and M. Thomasset, eds. (Riverside, CA: Vitamin D Workshop, Inc., University of CA), pp. 105–111.

Haddad, 1995, Plasma vitamin D-binding protein (Gc-globulin), J. Steroid Biochem. Mol. Biol., 53, 1, 10.1016/0960-0760(95)00104-8

Haddad, 1981, Vitamin D plasma binding protein. Turnover and fate in the rabbit, J. Clin. Invest., 67, 1550, 10.1172/JCI110186

Harrison, 1953, The Fanconi syndrome, J. Chron. Dis., 7, 346, 10.1016/0021-9681(58)90091-2

Keenan, 1991, The uptake and metabolism of 25-hydroxyvitamin D3 and vitamin D binding protein by cultured porcine kidney cells, Int. J. Biochem., 23, 1225, 10.1016/0020-711X(91)90220-H

Mendel, 1989, The free hormone hypothesis, Endocr. Rev., 10, 232, 10.1210/edrv-10-3-232

Moestrup, 1995, Evidence that epithelial glycoprotein 330/megalin mediates uptake of polybasic drugs, J. Clin. Invest., 96, 1404, 10.1172/JCI118176

Moestrup, 1996, Megalin-mediated endocytosis of transcobalamin-vitamin-B12 complexes suggests a role of the receptor in vitamin B12 homeostasis, Proc. Natl. Acad. Sci. USA, 93, 8612, 10.1073/pnas.93.16.8612

Moestrup, 1998, β2-glycoprotein-I (apolipoprotein H) and β2-glycoprotein-I-phospholipid complex harbor recognition site for the endocytic receptor megalin, J. Clin. Invest., 102, 902, 10.1172/JCI3772

Omdahl, 1980, In vitro regulation of kidney 25-hydroxyvitamin D3-hydroxylase enzyme activities by vitamin D3 metabolites, J. Biol. Chem., 255, 7460, 10.1016/S0021-9258(20)79726-7

Porto, 1991, Receptor-mediated endocytosis of an extracellular steroid-binding protein (TeBG) in MCF-7 human breast cancer cells, Endocrinology, 129, 436, 10.1210/endo-129-1-436

Porto, 1995, Receptors for androgen-binding proteins, J. Steroid Biochem. Mol. Biol., 53, 1, 10.1016/0960-0760(95)00111-C

Saito, 1994, Complete cloning and sequencing of rat gp330/“megalin.” A distinctive member of the low density lipoprotein receptor gene family, Proc. Natl. Acad. Sci. USA, 91, 9725, 10.1073/pnas.91.21.9725

Stefansson, 1995, gp330 on type II pneumocytes mediates endocytosis leading to degradation of pro-urokinase, plasminogen activator inhibitor-1 and urokinase-plasminogen activator inhibitor-1 complex, J. Cell. Sci., 108, 2361, 10.1242/jcs.108.6.2361

Siiteri, 1986, Changing concepts of active androgens in blood, Clin. Endocrinol. Metab., 15, 247, 10.1016/S0300-595X(86)80023-8

Siiteri, 1982, The serum transport of steroid hormones, Recent Prog. Horm. Res., 38, 457

St. John, 1992, Determinants of intact parathyroid hormone and free 1,25-dihydroxyvitamin D levels in mild and moderate renal failure, Nephron, 61, 422, 10.1159/000186960

Takeyama, 1997, 25-hydroxyvitamin D3 1 alpha-hydroxylase and vitamin D synthesis, Science, 277, 1827, 10.1126/science.277.5333.1827

Teranishi, 1983, Demonstration of vitamin D-binding protein in the urine of Itai-Itai disease patients, Toxicol. Lett., 15, 7, 10.1016/0378-4274(83)90161-3

Willnow, 1992, Low density lipoprotein receptor-related protein (LRP) and gp330 bind similar ligands, including plasminogen activator/inhibitor complexes and lactoferrin, an inhibitor of chylomicron remnant clearance, J. Biol. Chem., 267, 26172, 10.1016/S0021-9258(18)35732-6

Willnow, 1996, Defective forebrain development in mice lacking gp330/megalin, Proc. Natl. Acad. Sci. USA, 93, 8460, 10.1073/pnas.93.16.8460

Yang, 1990, Mapping and conservation of the group-specific component gene in mouse, Genomics, 7, 509, 10.1016/0888-7543(90)90193-X